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E-2: 作品数：506被引量：854H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：张恒斌胡晓璇吴骏徐龙伢王清遐更多>>; 相关机构：中国科学院诺瓦提斯公司北京大学江西江铃控股有限公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划广东省自然科学基金更多>>

Synthesis of Indole-Fused Eight-Membered Oxa-Rings via Palladium-Catalyzed Asymmetric[4+4]Cycloaddition of Indole-2,3-Quinodimethanes with 2-Alkylidenetrimethylene Carbonates: 《Chinese Journal of Chemistry》2024年第24期3393-3398,共6页Xinhao Lu Yi Wang Chenghan He Yang-Zi Liu Wei-Ping Deng; support from the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2022R01007);the NSFC(22171082,22201253);the Start-up Research Grant from Zhejiang Normal University;the Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism.; We report a palladium-catalyzed asymmetric[4+4]cycloaddition reaction between 2-alkylidenetrimethylene carbonate and electron-deficient indole-2,3-quinodimethanes(IQDMs).This reaction features exclusive regioselectivi...; 关键词：Pd-catalyzed Asymmetric[4+4]cycloaddition Indole-2 3-quinodimethanes 2-Alkylidenetrimethylene carbonates Indole-fused eight-membered oxa-rings

A Highly Selective and Sensitive Fluorescent Probe Recognition for Co^2＋ in Aqueous Media Based on 8-Hydroxyquinolin-2- carbaldehyde-2-pyridylformylhydrazone Derivative: 《Chinese Journal of Chemistry》2016年第12期1329-1334,共6页Keli Zhong Jie Zhao Xue Zhou Shuhua Hou Yanjiang Bian Jianrong Li Lijun Tang; A new （8-hydroxyquinolin-2-yl）methylene picolinohydrazide derivative （L） has been successfully synthesized and characterized. The probe L displays high selectivity to Co^2＋ in CH3CN/HEPES （1：1, V/ V, 10 mmol.L^...; 关键词：fluorescent probe Co^2＋ recognition aqueous media environmental

Design, Synthesis and Preliminary Biological Evaluation of Purine-2,6-diamine Derivatives as Cyclin-dependent Kinase （CDK） Inhibitors: 《Chinese Journal of Chemistry》2013年第9期1181-1191,共11页Junhua Wang Quande Wang Liangren Zhang Hao Fang; the National Natural Foundation Research Grant，the Shandong Provincial Natural Science Foundation，the Program for New Century Excellent Talents in University，Independent Innovation Foundation of Shandong University，the Open Research Fund of State Key Laboratory of Natural and Biomimetic Drugs in Peking University; Novel purine-2,6-diamine derivatives were designed and synthesized as cyclin-dependent kinase （CDK） inhibi- tors. According to the preliminary biological evaluation, most of the compounds show good inhibitory activi...; 关键词：purine derivatives CDK inhibitors antitumor agents regulation of cell cycle

Influence of Temperatures on the Tautomerism of the N-（1H- Imidazoline-2-yl）-lH-benzimidazol-2-amine and Investigation of Its Electrochemical Behaviour: 《Chinese Journal of Chemistry》2012年第2期400-404,共5页Servi, Suleyman Genc, Murat Saydam, Sinan; Synthesis of N-（1H-imidazoline-2-yl）-lH-benzimidazol-2-amine was carried out under microwave irradiation （MWI） conditions. Dynamic 1H NMR investigation of N-（lH-imidazoline-2-yl）-lH-benzimidazol-2-amine compound...; 关键词：BENZIMIDAZOLE TAUTOMERISM dynamic NMR cyclic voltammetry

An Efficient Synthesis of 3,3＇,4,4＇-Tetrahydro-4,4＇-bibenzo- [e][1,3]oxazine-2,2＇-dione Derivatives with the Aid of Low-valent Titanium: 《Chinese Journal of Chemistry》2011年第11期2465-2470,共6页窦国兰孙芳赵玄史达清; Project supported by the National Natural Science Foundation of China （No. 21072144） and the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions （No. 10KJAI50049）.; Synthesis of 3,3＇,4,4＇-tetrahydro-4,4＇-bibenzo[e][1,3]oxazine-2,2＇-diones via reaction of salicylidendphenylhy- drazone and triphosgene with the aid of low-valent titanium reagent is described. This method has the...; 关键词：synthesis design benzo[e][1 3]oxazine-2 2＇-diones low-valent titanium reagent radical reactions

Copper(Ⅱ) and 1,1 ＇-Trimethylene-2,2＇-biimidazole-promoted Arylation of Acetylacetone with Aryl Iodides: 《Chinese Journal of Chemistry》2011年第2期309-313,共5页Liu Jianli Zeng Runsheng Zhou Chunmei Zou Jianping; Project supported by tile National Natural Science Foundation of China （No. 20772088）.Acknowledgements We would like to thank good suggestions from Ma, Dawei of Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, China.; A new and efficient way was developed to carry out the reaction of acetylacetone with aryl iodides under the assistance of Cu（II） and 1, 1＇-trimethylene-2,2＇-biimidazole at 100℃. 3-Aryl-2,4-pentanediones were obt...; 关键词：Cu（II）-promoted arylation reaction 1 1＇-trimethylene-2 2＇-biimidazole 3-aryl-2 4-pentanedione

Synthesis of Certain 3-Aminopyrazolo[5,4-b]pyridine and 3,4-Substituted Pyrido[2′,3′：3,4]pyrazolo[5,1-c][1,2,4]triazine Derivatives: 《Chinese Journal of Chemistry》2007年第12期1887-1891,共5页EL-LOUH, Ali Khader Khalil ABUNADA, Nada Mohamed EL-SHOUBAKI, Mohamed; 2-Thioxo-1,2-dihydropyridine derivatives 2a, 2b were reacted with methyl iodide to give 2-methylthiopyridines 3a, 3b, which were reacted with hydrazine hydrate to produce 3-aminopyrazolo[5,4-b]pyridines 4a, 4b. Compou...; 关键词：pyrazolo[3 4-b]pyridine pyrido[2′ 3′ ： 3 4]pyrazole[5 1-c] [ 1 2 4]triazine 2-arylmethylidene-2-cyanothioacetamine 2-thioxopyridine

A Practical Route to Synthesize 3,4-O-Isopropylidene-2- azidophytosphingosine from D-Galactose: 《Chinese Journal of Chemistry》2007年第8期1069-1071,共3页丁宁刘运鹏吕国凯李英霞; An efficient and practical route to synthesize （2S,3S,4R）-2-azido-3,4-O-isopropyllidene-1,3,4-octadecanetriol from D-galactose in 18% overall yield was described, which required ten steps of reactions and only four ...; 关键词：GLYCOLIPID GLYCOSPHINGOLIPID PHYTOSPHINGOSINE azidophytosphingosine synthesis

Studies on Interaction between 4-（4-Hydroxybut-2-ynyloxy）-3-（phenylsulfonyl）-1,2,5- oxadiazole-2-oxide and Bovine Serum Albumin by Spectroscopic Method被引量：13: 《Chinese Journal of Chemistry》2006年第8期1050-1053,共4页孙绍发项光亚吴汉娜刘义; Project supported by the National Natural Science Foundation of China （Nos. 30570015, 20373051 ）, the Natural Science Foundation of Hubei Province （Nos. 2006ABA333, 2005ABC002）, and the Science Foundation of Hubei Provincial Educational Department （No. D200528003）, and the Science Research Foundation of Chinese Ministry of Education （No. [2006]8IRT0543）.; The interaction between 4-（4-hydroxybut-2-ynyloxy）-3-（phenylsulfonyl）-1,2,5-oxadiazole-2-oxide （FB） and bovine serum albumin （BSA） was studied by spectroscopic methods including fluorescence and UV-Vis absorpt...; 关键词：fluorescence quenching thermodynamic parameter bovine serum albumin 4-（4-hydroxybut-2-ynyloxy）-3-（phenylsulfonyl）- 1 2 5-oxadiazole-2-oxide

Chiral Fluorescent Receptors Based on （R）-1,1＇-Binaphthylene-2,2＇-bisthiourea： Synthesis and Chiral Recognition被引量：1: 《Chinese Journal of Chemistry》2005年第6期757-761,共5页隗兰华何永炳徐括喜刘顺英孟令芝

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