GLYCOLIPID

作品数：26被引量：43H指数：4
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相关领域：医药卫生更多>>
相关作者：姜桂珍王则能阳振乐张蕾叶新山更多>>
相关机构：北京大学中国科学院植物研究所更多>>
相关期刊：《Cellular & Molecular Immunology》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》《Chinese Medical Journal》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划福建省自然科学基金中国博士后科学基金更多>>
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Corynebacterium parakroppenstedtii secretes a novel glycolipid to promote the development of granulomatous lobular mastitis
《Signal Transduction and Targeted Therapy》2024年第11期5250-5266,共17页Ran Liu Zixuan Luo Chong Dai Yuchen Wei Shuqing Yan Xinwen Kuang Kuan Qi Aisi Fu Yinxin Li Shuai Fu Zhengning Ma Wen Dai Xiao Xiao Qing Wu Haokui Zhou Yan Rao Jingping Yuan Ting Shi Zixin Deng Chuang Chen Tiangang Liu 
supported by the National Key Research and Development Program of China(2018YFA0900400 to T.L.);Leading Talents of the Ten Thousand Talents Program to T.L.,Young Elite Scientists Sponsorship Program by China Association for Science and Technology to R.L.,the Shenzhen Institute of Synthetic Biology Scientific Research Program(Z.X.and R.L.);funding from State Key Laboratory of Microbial Metabolism,Shanghai Jiao Tong University(MMLZD24-01);the grants from The Interdisciplinary Innovative Talents Foundation from Renmin Hospital of Wuhan University(JCRCFZ-2022-015)to C.C.;the Fundamental Research Funds for the Central Universities(2042019kf0229)to C.C.;the Natural Science Foundation of Hubei Province(2023AFB701)to C.C.
Granulomatous lobular mastitis(GLM)is a chronic idiopathic granulomatous mastitis of the mammary gland characterized by significant pain and a high propensity for recurrence,the incidence rate has gradually increased,...
关键词：PREVENTION DIAGNOSIS TREATMENT 
A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safety
《Bioactive Materials》2024年第8期486-498,共13页Seo-Hyeon Bae Soyeon Yoo Jisun Lee Hyo-Jung Park Sung Pil Kwon Harin Jin Sang-In Park Yu-Sun Lee Yoo-Jin Bang Gahyun Roh Seonghyun Lee Sue Bean Youn In Woo Kim Ho Rim Oh Ashraf K.El-Damasy Gyochang Keum Hojun Kim Hyewon Youn Jae-Hwan Nam Eun-Kyoung Bang 
supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(No.NRF-2021M3E5E3080563,RS-2023-00229101);the Ministry of Food and Drug Safety(No.22213MFDS421);the Korea Institute of Science and Technology(KIST)Institutional Program(No.2E32852);H.Kim was supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(No.RS-2023-00209955);the Korea Institute of Science and Technology(KIST)Institutional Program(No.2E33111);J.H.Nam was supported by grants from the Ministry of Food and Drug Safety(grant number 22213MFDS421);partially supported by the Brain Korea 21 Four Program.H.Youn was supported by a grant from the Ministry of Food and Drug Safety(RS-2023-00217026).
The rapid development of messenger RNA(mRNA)vaccines formulated with lipid nanoparticles(LNPs)has contributed to control of the COVID-19 pandemic.However,mRNA vaccines have raised concerns about their potential toxici...
关键词：Trehalose glycolipid Lipid nanoparticle mRNA vaccine Toxicity IMMUNOGENICITY 
Hydrogen bond-assisted 1,2-cis O-glycosylation under mild hydrogenolytic conditions被引量：1
《Chinese Chemical Letters》2023年第4期313-317,共5页Gefei Li Yanlong Luo Juan Mo Masato Noguchi Jie Jing Zhenyang Luo Shin-ichiro Shoda Xin-Shan Ye 
financially supported by the State Key Laboratory of Natural and Biomimetic Drugs (No. K202216);the National Natural Science Foundation of China (Nos. 21907004 and 81821004);the National Key R&D Program of China (No.2018YFA0507602);the Beijing Outstanding Young Scientist Program(No. BJJWZYJH01201910001001);a Grant-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology,Japan。
A hydrogen bond-assisted α-selective glycosylation reaction by using 4,6-dibenzyloxy-1,3,5-triazin-2-yl(DBT) β-glycosyl donors was developed for the efficient construction of 1,2-cis-α-glycosidic bond in natural pr...
关键词：O-GLYCOSYLATION Hydrogen bond α-Selectivity GLYCOLIPID Natural product 
Apocynum venetum Feed Affects the Serum Metabolism of Tan-sheep through the Amino Acid and Glycolipid Metabolic Pathways
《Animal Husbandry and Feed Science》2022年第4期25-32,共8页Li Guoqi Jin Changqing Chen Yanyun 
Ningxia Natural Science Foundation(2020AAC03076).
[Objective]The paper was to explore the effects of Apocynum venetum diet on nutritional metabolism of Tan sheep.[Method]Forty Ningxia Tan sheep were randomly divided into 4 groups(A,B,C and D),with 10 sheep in each gr...
关键词：Apocynum venetum Granulated feed Tan-sheep SERUM Differential metabolites Metabolic pathways 
Polymorphism of Kdo-Based Glycolipids:The Elaborately Determined Stable and Dynamic Bicelles
《CCS Chemistry》2022年第7期2228-2238,共11页Yingle Feng Long Li Qiqige Du Lu Gou Lei Zhang Yonghai Chai Ran Zhang Tongfei Shi Guosong Chen 
the financial support from the National Natural Science Foundation of China(grant nos.51721002,21861132012,91956127,and 21975047);NSFC/China(grant nos.21674114 and 91956127)for financial support;supported by the Shanghai Municipal Science and Technology Major Project(grant no.2018SHZDZX01)and ZJ Lab.
Understanding how the diversity of glycolipids,including how their chemical structures and composition affect their biological functions,is a remarkable fundamental challenge.In this work,we employed a rare monosaccha...
关键词：GLYCOLIPID KDO SELF-ASSEMBLY BICELLES 
IL-22 and its interaction with amino acid and glycolipid metabolite in polycystic ovary syndrome (PCOS) patients被引量：1
《Chinese Medical Journal》2022年第10期1258-1260,共3页Xinyu Qi Qixing ie Yanli Pang Jie Qiao 
This study was supported by grants from the National Key Research and Development Program of China(Nos. 2018YFC1003900, 2018YFC1003200);the National Natural Science Foundation of China(Nos. 82022028, 81730038, 82001506);the CAMS Innovation Fund for Medical Sciences(No. 2019-I2M-5-001);the Key Clinical Projects of Peking University Third Hospital(No. BYSYZD2019020);the China Postdoctoral Science Foundation Grant(No. 2019M660367)。
To the Editor:Polycystic ovary syndrome(PCOS)is a complex endocrine and metabolic disorder affecting women in the reproductive age,with a prevalence of 5.61%.However,the pathogenesis of this complex and heterogeneous ...
关键词：metabolism PATIENTS PATHOGENESIS 
Regulation of pathological BBB restoration via nanostructured ROS-responsive glycolipid-like copolymer entrapping siVEGF for glioblastoma targeted therapeutics被引量：2
《Nano Research》2022年第2期1455-1465,共11页Lijuan Wen Yu Peng Kai Wang Zhihua Huang Shiying He Ruiwen Xiong Longping Wu Fengtian Zhang Fuqiang Hu 
supported by the National Natural Science Foundation of China(No.81973267);the National Science Foundation of Zhejiang Province,China(No.D19H30001);the Project of Gannan Medical University(No.ZD201903);the PhD Start-up Fund of Gannan Medical University(No.QD201908).
Glioblastoma(GBM)is one of the malignant brain tumors with high mortality and no curative treatments.Abnormally elevated vascular endothelial growth factor(VEGF)in GBM seriously disrupts the blood brain barrier(BBB)wi...
关键词：GLIOBLASTOMA ROS-responsive siRNA blood brain barrier COPOLYMER 
Mechanisms of Dangua Recipe in Improving Glycolipid Metabolic Disorders Based on Transcriptomics被引量：7
《Chinese Journal of Integrative Medicine》2022年第2期130-137,共8页HENG Xian-pei WANG Zhi-ta LI Liang YANG Liu-qing HUANG Su-ping 
the National Natural Science Foundation of China(No.81873213,81473550);the Natural Science Foundation of Fujian Province(No.2017J01213,2016J0146);the Inn ovation Fund of Medical Science of Fujian Provi nee(No.2017-CX-42),China。
Objective:To explore the mechanisms of Dangua Recipe(DGR)in improving glycolipid metabolism based on transcriptomics.Methods:Sprague-Dawley rats with normal glucose level were divided into 3 groups according to a rand...
关键词：TRANSCRIPTOMICS Dangua Recipe glycolipid metabolism NAMPT therapeutic target Chinese medicine 
Brexpiprazole caused glycolipid metabolic disorder by inhibiting GLP1/GLP1R signaling in rats被引量：1
《Acta Pharmacologica Sinica》2021年第8期1267-1279,共13页De-juan Li Qin Yue Lu Liu Ke-ke Che Xue-mei Liu Chang-hua Hu 
financially supported by grants by Chongqing Natural Science Foundation,China(cstc2020jcyj-msxmX0424);Venture&Innovation Support Program for Chongqing Overseas Returnees(cx2018089).
Brexpiprazole(Bre)is a new multi-target antipsychotic drug(APD)approved by the US FDA in 2015,and shows good therapeutic potential.But it lacks assessments on the metabolic side effects,which obstructs the treatment o...
关键词：SCHIZOPHRENIA brexpiprazole glycolipid metabolic disorder insulin resistance GLP1/GLP1R signaling LIRAGLUTIDE 
Relationship between serum osteocalcin level and glucose and lipid metabolism in patients with type 2 diabetes mellitus complicated with nonalcoholic fatty liver disease
《Journal of Hainan Medical University》2019年第9期20-23,共4页Ying Shen Lei-Qun Lu Ping Gao 
Objective: To study the relationship between serum osteocalcin level and glucose and lipid metabolism in patients with type 2 diabetes mellitus complicated with nonalcoholic fatty liver disease. Methods: The clinical ...
关键词：Type 2 diabetes MELLITUS NONALCOHOLIC FATTY liver disease Serum OSTEOCALCIN GLYCOLIPID metabolism 
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