相关期刊:《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》《World Journal of Diabetes》《American Journal of Molecular Biology》更多>>
Supported by National Natural Science Foundation of China,No.82170651;and the Research Support Fund of Hubei Microcirculation Society,No.HBWXH2024(1)-1.
Intrapancreatic fat deposition(IPFD)has garnered increasing attention in recent years.The prevalence of IPFD is relatively high and associated with factors such as obesity,age,and sex.However,the pathophysiological me...
BACKGROUND Wernicke encephalopathy is a neurological disorder caused by thiamine deficiency,commonly seen in alcoholic populations but also involving other circumstances that may lead to thiamine deficiency.The recogn...
This editorial focuses on the relationship between nonalcoholic fatty pancreas disease(NAFPD)and the development and remission of type 2 diabetes(T2D).NAFPD is characterized by intrapancreatic fatty deposition associa...
To the Editor:We read with considerable interest the paper of Shree Harini and Ezhilarasan,summarizing the possible pathophysiological connections between the modulators of canonical Wnt/β-catenin pathway and nonalco...
National Natural Science Foundation of China(81870404,81670518,81170392);Guangdong Science and Technology Department(2014A020212118);Chinese Foundation for Hepatitis Prevention and Control(TQGB20140083);China postdoctoral science foundation(2020M683128).
Background and Aims:The redefinition of metabolic-as-sociated fatty liver disease(MAFLD)from nonalcoholic fat-ty liver disease(NAFLD)has caused a revolution in clinical practice,and the characteristics of patients wit...
supported by the National Natural Science Foundation of China(No.81570781)。
Objective:To investigate effects of berberine(BBR)on cholesterol synthesis in HepG2 cells with free fatty acid(FFA)-induced steatosis and to explore the underlying mechanisms.Methods:A steatosis cell model was induced...
We earlier reviewed how obesity has assumed an endemic/pandemic proportions that has resulted in escalating incidence and prevalence of associated escalating worldwide incidence of Metabolic Syndrome(MetS)with non alc...
supported by grants from the Ministry of Science&Technology of China(2016YFE0107400);the National Natural Science Foundation of China(81272436,81572356,81871997,81500665 and 82070588);High Level Creative Talents from Department of Public Health in Zhejiang Province(S2032102600032);Project of New Century 551 Talent Nurturing in Wenzhou。
Background: Nonalcoholic fatty liver disease(NAFLD) is one of the main liver diseases, and its pathologic profile includes nonalcoholic fatty liver(NAFL) and nonalcoholic steatohepatitis(NASH). However, there is no re...
Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in recent years.It describes fat accumulation in the pancreas with insignificant alcohol consumption,b...
YSZ received funding from National Institutes of Health(K99CA201603,R00CA201603,R21EB025270,R21EB026175,R01EB028143,R03EB027984);National Science Foundation(1935105);Brigham Research Institute New England Anti-Vivisection Foundation,and American Fund for Alternatives to Animal Research(AFAAR).AZ received funding from National Institutes of Health(K08DK113244,R01MD012579);SD received funding from National Institutes of Health(R01MD012579-UT20664DS).
This study presents a simple and robust three-dimensional human hepatic tissue model to emulate steatotic and fibrotic conditions and provide an in vitro model for drug testing and mechanistic studies.Using a photolit...