supported by the National Natural Science Foundation of China(No.31870934);the Natural Science Foundation for Young Scientists of Shanxi Province(No.202103021223100),China.
Three-dimensional(3D)hydrogel models play a crucial role in tissue engineering for promoting tissue regeneration.A biomimetic microchannel network system in the 3D hydrogel model is necessary for optimal cellular func...
supported by the National Natural Science Foundation of China(22077092);the Training Program of the Major Research Plan of the National Natural Science Foundation of China(91959123);the Open Project Program of the State Key Laboratory of Radiation Medicine and Protection(GZK1202132,GZK1202017,GZK1202140);the Priority Academic Program Development of Jiangsu Higher Education Institutions。
Controlled drug delivery holds great potential for effective tumor treatment owing to the merits of overcoming drug resistance and improving therapeutic efficacy while minimizing systemic toxicity.However,accurate and...
supported by Beijing Natural Science Foundation(No.2222051);the National Natural Science Foundation of China(No.81973442).
Combining the noncovalent and covalent interactions,a series of peptide amphiphiles were designed de novo and synthesized to architect functional assemblies by means of photochemistry.The strand of peptide sequence wa...
Environmental Restoration and Conservation Agency,Grant/Award Number:JPMEERF20221R03;Japan Society for the Promotion of Science,Grant/Award Number:21H02004;Leading Initiative for Excellent Young Researchers,and MEXT,Japan。
Hollow polymer particles are widely used in various industries as coatings and thermal insulation materials.The encapsulation capabilities of various functional molecules and/or nanomaterials also provide access to ap...
This study was supported by the Innovation research program[HHKT-00-03];the National Natural Science Foundation of China[grant numbers 82170929,81970908,51901003,81200814,and 81771039].
Guided bone regeneration membranes have been effectively applied in oral implantology to repair bone defects.However,typical resorbable membranes composed of collagen(Col)have insufficient mechanical properties and hi...
supported by the National Natural Science Foundation of China(12032007,31971242);the Natural Science Foundation of Chongqing(cstc2020jcyj-msxmX0330);the Project of Science and Technology of Chongqing Yuzhong District(20170119,20170113);the Project of Tutorial System of Medical Undergraduate in Lab Teaching&Management Center in Chongqing Medical University(LTMCMTS202003);the National Project of University Students Innovation and Entrepreneurship Training Program(201910631002);the Project of‘Ying Yao Program’for College Student in School of Basic Medical Sciences in ChongqingMedical University(JCYY202003).
Damage to the skin causes physiological and functional issues.The most effective treatment approach is the use of wound dressings.Silk fibroin(SF)is a promising candidate biomaterial for regulating wound healing;howev...
YSZ received funding from National Institutes of Health(K99CA201603,R00CA201603,R21EB025270,R21EB026175,R01EB028143,R03EB027984);National Science Foundation(1935105);Brigham Research Institute New England Anti-Vivisection Foundation,and American Fund for Alternatives to Animal Research(AFAAR).AZ received funding from National Institutes of Health(K08DK113244,R01MD012579);SD received funding from National Institutes of Health(R01MD012579-UT20664DS).
This study presents a simple and robust three-dimensional human hepatic tissue model to emulate steatotic and fibrotic conditions and provide an in vitro model for drug testing and mechanistic studies.Using a photolit...
the H2020-MSCA-RISE-2016,SECOND.R.I.,Grant Agreement No 734391;Progetto Premiale di AREA SCIENCE PARK“OPEN LAB-A System of Open Research Facilities”for the support。
The main driving idea of the present study was the comparison between two different chemical modifications of hyaluronic acid(HA)followed by the development of nanocomposite hydrogels directly in situ by biomineraliza...
financially supported by the National Natural Science Foundation of China(Nos.21574041 and 21374030);Large Instruments Open Foundation of East China Normal University(No.20151006)
Block copolymers poly(endo-N-3,5-bis(trifluoromethyl)biphenyl-norbornene-pyrrolidine)-block-poly(exo-N-(cinnamoyloxyethyl)-7-oxanorborn-5-ene-2,3-dicarboximide)(endo-PTNP-b-exo-PCONBI) and poly(exo-N-3,5-bi...
he multiple antibiotic resistance regulatory protein(MarR) binds to two promoter sites on the marO operator in Escherichia coli.Our study showed that more than one MarR dimer proteins bound to either of its two promot...