云南高校图书馆联盟文献共享服务平台- LIRAGLUTIDE

LIRAGLUTIDE: 作品数：76被引量：187H指数：9; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杨刚毅李伶张志红杨艳杜林更多>>; 相关机构：重庆医科大学山西医科大学华中科技大学南京大学医学院附属鼓楼医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金武汉市创新人才开发资金国家教育部博士点基金中国博士后科学基金更多>>

Enhanced oral drug delivery by mimicking natural amino acid and oligopeptide absorption route: 《Nano Research》2025年第2期525-540,共16页Ruinan Wu Xiaoxing Fan Licheng Wu Liyun Xing Jinxia Kong Zhou Zhou Jingyuan Wen Lian Li Yuan Huang; This work was supported by the National Key Research and Development Program of China(No.2021YFE0115200);the Regional Innovation and Development Joint Fund of National Natural Science Foundation of China(No.U22A20356).; Oral delivery of protein and peptide drugs presents considerable challenges due to their susceptibility to digestive enzymes in gastrointestinal(Gl)tract and low efficiency of transepithelial transport.Herein,inspired...; 关键词：oral drug delivery amino acid absorption route oligopeptide absorption route LIRAGLUTIDE

Protective Effect of Liraglutide on Early Renal Fibrosis in Diabetes Mice: 《Journal of Biosciences and Medicines》2025年第1期84-91,共8页Xiaolan Ke Te’an Ma; Background: In recent years, studies have shown that liraglutide may delay the progression of renal fibrosis by inhibiting renal fibrosis signaling pathways and reducing collagen deposition. TGF-β1 and E-Cadherin pla...; 关键词：LIRAGLUTIDE DIABETES Renal fibrosis TGF-β1 E-CADHERIN

Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway: 《Acta Pharmacologica Sinica》2024年第8期1604-1617,共14页Xia-yun Ni Xiao-jun Feng Zhi-hua Wang Yang Zhang Peter J.Little Yang Cao Suo-wen Xu Li-qin Tang Jian-ping Weng; supported by grants from the National Key R&D Program of China(Grant No.2021YFC2500500);National Natural Science Foundation of China(No.82003740,No.82174031,No.82070464,No.82370444,No.82102804);the Doctoral Research Fund(RC2021015);the China Postdoctoral Science Foundation(No.2021M693102);Scientific Research Project of Anhui Provincial Education Department(2022AH040184);supported by the Program for Innovative Research Team of The First Affiliated Hospital of USTC(CXGG02);Anhui Provincial Key Research and Development Program(Grant No.202104j07020051);Anhui Provincial Natural Science Foundation(Grant No.2208085J08).; Heart failure with preserved ejection fraction(HFpEF)is closely associated with metabolic derangement.Sodium glucose cotransporter-2 inhibitors(SGLT2i)and glucagon-like peptide-1 receptor agonists(GLP-1RA)exert anti-H...; 关键词：HFpEF empagliflozin LIRAGLUTIDE ERBB4 snRNA-seq

Neuroprotective effect of liraglutide and memantine in a rat model of Alzheimer’s disease被引量：1: 《Asian Pacific Journal of Tropical Biomedicine》2024年第5期207-214,共8页Duaa M.Bakhshwin Foziya W.Alhalabi Mohamad Omar Barasheed Ahmed M.Bakhshwin Maha H.Jamal Mohammed A.Bazuhair Fatemah O.Kamel Rania M.Magadmi Zoheir A Damanhouri Samar M.Alsaggaf; funded by the Deanship of Scientific Research(DSR)at King Abdulaziz University,Jeddah,under grant No.G:455-248-1442。; Objective:To assess the effect of memantine combined with liraglutide on aluminum chloride(AlCl_(3))and D-galactose(D-GAL)-induced neurotoxicity in rats.Methods:Male Wistar rats were divided into 5 groups of 5 animals...; 关键词：Alzheimer’s disease Cognitive function Glucagonlike peptide-1 LIRAGLUTIDE MEMANTINE

Liraglutide improves the inflammatory response in metabolic associated fatty liver disease through stimulator of interferon genes pathway: 《China Medical Abstracts(Internal Medicine)》2024年第1期52-52,共1页方琼琼; Objective To investigate the mechanism by which Liraglutide improves the inflammatory response in metabolic associated faty liver disease (MAFLD) by regulating the interferon gene stimulating factor (STING)signaling p...; 关键词：C57BL/6J liver INFLAMMATORY LIRAGLUTIDE

A Study on Enhancing Pancreatic Islet Function in Type 2 Diabetes and Coronary Heart Disease Patients with Liraglutide and Metformin Combination Therapy被引量：1: 《Proceedings of Anticancer Research》2023年第6期116-121,共6页Chunxiao Yang; Objective:To investigate the impact of combining liraglutide with metformin on the enhancement of pancreatic islet function in patients with type 2 diabetes and coronary heart disease.Methods:60 patients with type 2 d...; 关键词：LIRAGLUTIDE METFORMIN Type 2 diabetes Coronary heart disease Pancreatic islet function

Liraglutide Suppresses Myocardial Fibrosis Progression by Inhibiting the Smad Signaling Pathway被引量：2: 《Current Medical Science》2023年第5期955-960,共6页Wen SUN Hong MI De-ying HE Wen LI Yi-yan SONGYANG; supported by grants from the Natural Science Foundation of Hubei Province(No.2022CFB671);Health Research Project of Hubei Province(No.WJ2023F020);Hubei Province Key Laboratory Open Project(No.2021KFY023).; Objective Liraglutide is a commonly used hypoglycemic agent in clinical practice,and has been demonstrated to have protective effects against the development of cardiovascular disease.However,its potential role in myo...; 关键词：LIRAGLUTIDE myocardial fibrosis TGFβl SMAD

Cost-effectiveness Analysis of Insulin Degludec and Liraglutide Injection in the Treatment of Type 2 Diabetes: 《Asian Journal of Social Pharmacy》2023年第3期281-295,共15页Sun Quan Zhang Fang Dong Li; Objective To analyze the cost-effectiveness of insulin degludec and liraglutide injection(IDegLira)compared with insulin glargine plus insulin aspart(IGar plus IAsp)in the treatment of type 2 diabetes mellitus(T2DM)ba...; 关键词：insulin degludec and liraglutide injection insulin glargine insulin aspart cost-effectiveness analysis

Exploration on the protective effect of liraglutide on renal injury in diabetic nephropathy rats based on ROS-NLRP3 inflammasomes: 《Discussion of Clinical Cases》2023年第3期18-24,共7页Jun Xue Xiuqi Ma Xuehui Wu Jiali He Weiling Song Hongju Li; Objective:To investigate the effect of liraglutide on diabetic nephropathy in rats and its regulatory mechanism.Methods:The diabetic nephropathy rat model was constructed with high-glucose-high-fat diet in combination...; 关键词：Diabetic nephropathy LIRAGLUTIDE ROS-NLRP3 inﬂammasome

Short-Term Effects of Liraglutide versus Vildagliptin on Insulin Secretion and Sensitivity in Type 2 Diabetes: A Single Blinded Randomized Controlled Trial (LIRAVIS Study)被引量：1: 《Journal of Diabetes Mellitus》2023年第1期45-57,共13页Martine Claude Etoa Etoga Estelle Amandine Well Simeon Pierre Choukem Mesmin Dehayem Francine Mendane Mekobe Anne Boli Ongmeb Astasselbe Hadja Inna Jean Claude Mbanya Eugene Sobngwi; Background: We aimed to evaluate the short-term metabolic effects of a GLP-1a, (liraglutide) versus a DPP-4i, (vildagliptin) in a group of sub-Saharan type 2 diabetes patients. Methods: We conducted a randomized contr...; 关键词：Insulin Sensitivity Insulin Secretion LIRAGLUTIDE VILDAGLIPTIN Incretinomimetics

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