MEMANTINE

作品数:32被引量:63H指数:4
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相关领域:医药卫生更多>>
相关作者:周杏琴张建康曹国宪徐希杰邹美芬更多>>
相关机构:佳木斯大学江苏省原子医学研究所佳木斯大学附属第一医院第四军医大学西京医院更多>>
相关期刊:《Advances in Alzheimer's Disease》《职业卫生与应急救援》《化学学报》《黑龙江医药科学》更多>>
相关基金:国家自然科学基金上海市教委科研基金国家高技术研究发展计划更多>>
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Neuroprotective effect of liraglutide and memantine in a rat model of Alzheimer’s disease被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2024年第5期207-214,共8页Duaa M.Bakhshwin Foziya W.Alhalabi Mohamad Omar Barasheed Ahmed M.Bakhshwin Maha H.Jamal Mohammed A.Bazuhair Fatemah O.Kamel Rania M.Magadmi Zoheir A Damanhouri Samar M.Alsaggaf 
funded by the Deanship of Scientific Research(DSR)at King Abdulaziz University,Jeddah,under grant No.G:455-248-1442。
Objective:To assess the effect of memantine combined with liraglutide on aluminum chloride(AlCl_(3))and D-galactose(D-GAL)-induced neurotoxicity in rats.Methods:Male Wistar rats were divided into 5 groups of 5 animals...
关键词:Alzheimer’s disease Cognitive function Glucagonlike peptide-1 LIRAGLUTIDE MEMANTINE 
Efficacy and Safety of Chinese Herbal Medicines Combined with Chemical Drugs for Alzheimer's Disease:A Systematic Review and Meta-Analysis
《World Journal of Traditional Chinese Medicine》2024年第1期1-13,共13页Li Xu Wen-Jun Chen Cai-Jun Tian Yan Zhang Yan Ma Tian-Hao Li Hong-Jie Liu Zhe Zhang 
supported by the 2019-2020 TCM Technology Development Project of Shandong Province(No.2019-0044);Guangdong Basic and Applied Basic Research Foundation(No.2019A1515010644);Project of Traditional Chinese Medicine Bureau of Guangdong Province(No.20201073);General Program of National Natural Science Foundation of China(No.82074306)。
Objective:To evaluate the efficacy and safety of Chinese herbal medicines(CHMs)combined with chemical drugs for the treatment of Alzheimer's disease(AD).Materials and Methods:Databases were searched to retrieve random...
关键词:Alzheimer's disease Chinese herbal medicine DONEPEZIL MEMANTINE META-ANALYSIS randomized controlled trials RIVASTIGMINE 
Effects of Citicoline Combined with Memantine on Cognitive Function and Activities of Daily Living in Patients with Vascular Dementia
《外文科技期刊数据库(文摘版)医药卫生》2022年第5期106-110,共5页SHAOYishun MAJuanjuan LURong 
Objective: to explore whether citicoline combined with memantine therapy can help patients return to normal life as soon as possible for the majority of patients with vascular dementia. Methods: selected 150 patients ...
关键词:CITICOLINE MEMANTINE vascular dementia 
Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer disease
《中国药理学与毒理学杂志》2021年第9期646-647,共2页WU Liang-miao ZHOU Xin-hua CAO Yi-wan Shing Hung MAK ZHA Ling LI Ning SU Zhi-yang HAN Yi-fan WANG Yu-qiang Maggie Pui Man Hoi SUN Ye-wei ZHANG Gao-xiao YANG Xi-fei ZHANG Zai-jun 
OBJECTIVE Alzheimer disease(AD)is a leading cause of dementia in elderly individuals and therapeutic options for AD are very limited.Over-activation of N-methyl-D-aspar⁃tate(NMDA)receptors,amyloidβ(Aβ)aggrega⁃tion,a...
关键词:Alzheimer disease MN-08 meman⁃tine nitrate 
Physiopathology of ischemic stroke and its modulation using memantine:evidence from preclinical stroke被引量:13
《Neural Regeneration Research》2021年第3期433-439,共7页Hilda Martínez-Coria Isabel Arrieta-Cruz María-Esther Cruz Héctor E.López-Valdés 
Ischemic stroke is the most common type of cerebrovascular disease and is caused by an interruption of blood flow in the brain.In this disease,two different damage areas are identifying:the lesion core,in which cells ...
关键词:focal ischemic stroke MEMANTINE NEUROPLASTICITY NEUROPROTECTION stroke therapy 
Effect of Artesunate vs Memantine in Aluminum Chloride Induced Model of Neurotoxicity in Rats
《Advances in Alzheimer's Disease》2020年第1期1-19,共19页Ahmed Shata Wagdi Elkashef Manal A. Hamouda Hanan Eissa 
Alzheimer disease is one of the commonest neurological diseases which is characterized by amyloid plaques accumulation in multiple brain regions. This study investigated the potential neuroprotective effect of artesun...
关键词:ARTESUNATE MEMANTINE AMMONIUM CHLORIDE NEUROTOXICITY 
Framework of treating Alzheimer’s dementia
《Brain Science Advances》2019年第2期82-93,共12页Yuan-Han Yang Rajka Liscic Jacqueline Dominguez 
the support by Neuroscience Research Center,Kaohsiung Medical University,KMU-TC108B01.
Current treatment paradigm in Alzheimer’s disease(AD)involves multiple approaches combining pharmacological and nonpharmacological intervention to mitigate the clinical symptoms,slow the progressive loss of cognitive...
关键词:DONEPEZIL RIVASTIGMINE GALANTAMINE MEMANTINE Alzheimer’s disease 
Investigating the inhibition of NMDA glutamate receptors in the basolateral nucleus of the amygdala on the pain and inflammation induced by formalin in male Wistar rats
《Frontiers in Biology》2018年第2期149-155,共7页Nima Heidary Hedayat Sahraei Mohammad Reza Afarinesh Zahra Bahari Gholam Hossein Meftahi 
BACKGROUND: The role of the amygdala in controlling emotional pain has been emphasized in several studies. In this study, the role of the NMDA glutamate receptors in the basolateral nucleus of the amygdala (BLA) in...
关键词:basolateral nucleus of amygdala formalin test INFLAMMATION licking time MEMANTINE 
Are memantine, methylphenidate and donepezil effective in sparing cognitive functioning after brain irradiation?被引量:1
《Journal of Cancer Metastasis and Treatment》2018年第1期694-701,共8页Rosa Wartena Dieta Brandsma Jose Belderbos 
One strategy to reduce neurocognitive deterioration in patients after brain irradiation is the use of neuroprotective medication.To generate up-to date knowledge regarding neuroprotective agents we performed a systema...
关键词:MEMANTINE DONEPEZIL METHYLPHENIDATE brain irradiation NEUROPROTECTION whole brain irradiation neuroprotective agent lung cancer 
Incorporation of Dihydroartemisinin into Memantine Through a Propriate Spacer to Make Hybrid with Enhanced Effects to Protect PC12 Cells from Corticosterone-caused Impairments
《Chemical Research in Chinese Universities》2017年第4期611-622,共12页ZHANG Lei ZHOU Fan ZHANG Laitao PENG Lizhi GUO Cuiping LUO Cheng CHEN Heru 
Supported by the National Natural Science Foundation of China(No.81172982), the Natural Science Foundation of Guang- dong Province of China(No.2015A030311012) and the Fundamental Research Funds for the Central Universities of China(No. 11615323).
Ten memantine(Mema)-dihydroartemisinin(DHA) ligands were designed and synthesized. Three types of isomers including α, β, and a defined y isomer were found in each intermediates(1a--1e). Type γ isomer was fir...
关键词:Artemisinm MEMANTINE Neuroprotection N-Methyl-D-aspartate(NMDA) receptor Depression 
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