DONEPEZIL

作品数：49被引量：122H指数：7
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相关领域：医药卫生更多>>
相关作者：金正均邱瑜陈红专王晓良张炜更多>>
相关机构：北京协和医学院上海第二医科大学中国医学科学院北京协和医学院中国海洋大学更多>>
相关期刊：《International Journal of Ophthalmology(English edition)》《中国处方药》《Neuroimmunology and Neuroinflammation》《药学学报》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家杰出青年科学基金广西壮族自治区自然科学基金更多>>
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Use of donepezil for neurocognitive recovery after brain injury in adult and pediatric populations:a scoping review
《Neural Regeneration Research》2024年第8期1686-1695,共10页Avery L.Miller Nathan K.Evanson J.Michael Taylor 
Division of Neurology,Cincinnati Children’s Hospital Medical Center(as a Medical Student Scholars Program award to ALM)。
There are few pharmacologic options for the treatment of cognitive deficits associated with traumatic brain injury in pediatric patients.Acetylcholinesterase inhibitors such as donepezil have been evaluated in adult p...
关键词：acetylcholinesterase inhibitor ADULT COGNITION DONEPEZIL PEDIATRICS traumatic brain injury 
Efficacy and Safety of Chinese Herbal Medicines Combined with Chemical Drugs for Alzheimer's Disease:A Systematic Review and Meta-Analysis
《World Journal of Traditional Chinese Medicine》2024年第1期1-13,共13页Li Xu Wen-Jun Chen Cai-Jun Tian Yan Zhang Yan Ma Tian-Hao Li Hong-Jie Liu Zhe Zhang 
supported by the 2019-2020 TCM Technology Development Project of Shandong Province(No.2019-0044);Guangdong Basic and Applied Basic Research Foundation(No.2019A1515010644);Project of Traditional Chinese Medicine Bureau of Guangdong Province(No.20201073);General Program of National Natural Science Foundation of China(No.82074306)。
Objective:To evaluate the efficacy and safety of Chinese herbal medicines(CHMs)combined with chemical drugs for the treatment of Alzheimer's disease(AD).Materials and Methods:Databases were searched to retrieve random...
关键词：Alzheimer's disease Chinese herbal medicine DONEPEZIL MEMANTINE META-ANALYSIS randomized controlled trials RIVASTIGMINE 
Effect of cerebralcare granule®combined with donepezil on Alzheimer’s disease
《Drug Combination Therapy》2023年第1期10-18,共9页Ming-Juan Yang Ou Qiao Du-Hong Xie Xin-Yu Zhang Ya-Ping Bo Xia Li Juan Wang Wen-Yuan Gao 
supported by the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine[grant numbers ZYYCXTD-D-202005];the Key Project at Central Government Level[grant numbers 2060302];the Special Project for Transformation of Scientific and Technological Achievements in Qinghai Province[grant numbers 2021-SF-150].
Background:The current prevalence of Alzheimer’s disease(AD)in the elderly has risen from 1%at 65 to 40%to 50%at 95,and the overall proportion is rising.Emerging evidence suggests that ros-driven oxidative stress is ...
关键词：Alzheimer’s disease cerebralcare granule® DONEPEZIL drug combination 
On the interaction of a donepezil-huprine hybrid with synthetic membrane models
《Neural Regeneration Research》2023年第2期333-334,共2页Pablo Zambrano 
Alzheimer's disease is the most prevalent type of dementia today,discovered and described by Alois Alzheimer in 1907.According to the World Alzheimer Report 2021,75%of people with dementia worldwide are undiagnosed,eq...
关键词：ALZHEIMER DISEASES 
Clinical study of acupuncture combined with medication for the elderly with Alzheimer disease
《Journal of Acupuncture and Tuina Science》2022年第6期464-469,共6页PANG Jing YIN Hongna SUN Zhongren XIA Kunpeng HONG Jue 
This work was supported by the Construction Project of Evidence-based Ability of Traditional Chinese Medicine(Improvement Evidence-based Ability of Specialized Diseases)[中医药循证能力建设项目(专科专病循证能力提升),No.2019XZZX-ZJ005];Research Project of Health Commission of Heilongjiang Province(黑龙江省卫生健康委科研课题,No.2019-192).
Objective:To observe the impact of mind-regulating acupuncture plus donepezil on the cognitive ability,mean cerebral blood flow velocity,event-related potential P300,and activities of daily living(ADL)in the aged pati...
关键词：Acupuncture Therapy Acupuncture Medication Combined DONEPEZIL Alzheimer Disease Activities of Daily Living Event-related Potentials P300 
Analysis of Clinical Efficacy of Donepezil and Ginkgo Biloba Leaves in the Treatment of Senile Dementia
《外文科技期刊数据库(文摘版)医药卫生》2022年第6期020-023,共4页WENXiaofei 
Objective: Alzheimer's disease is a very common clinical disease, and the incidence of diseases will increase with the increase of age. It is a common clinical geriatric disease and a neurological problem that is diff...
关键词：DONEPEZIL ginkgo biloba leaves TREATMENT senile dementia clinical efficacy 
Pseudoginsenoside-F11 attenuates cognitive dysfunction and tau phosphorylation in sporadic Alzheimer’s disease rat model被引量：3
《Acta Pharmacologica Sinica》2021年第9期1401-1408,共8页Lei Zhu Xiao-jie Hou Xiao-hang Che Ting-shuo Zhou Xiao-qi Liu Chun-fu Wu Jing-yu Yang 
We previously reported that pseudoginsenoside-F11(PF11),an ocotillol-type saponin,significantly ameliorated Alzheimer’s disease(AD)-associated cognitive defects in APP/PS1 and SAMP8 mice by inhibiting Aβaggregation ...
关键词：Alzheimer’s disease pseudoginsenoside-F11 Tau hyperphosphorylation insulin signaling pathway calpain I/CDK5 signaling pathway DONEPEZIL 
Meta-analysis of efficacy and safety of Donepezil in treating cognitive decline of Parkinson's disease
《Journal of Hainan Medical University》2021年第15期33-39,共7页Qiu-Ping Li Zhi-Bin Chen Tan Wang Hong-Yan Zhang 
National Natural Science Foundation of China(No.81760237);National Natural Science Foundation of China(No.81860243);Hainan province key R&D plan science and technology cooperation project in 2017(No.ZDYF2017170)。
Objective:To systematically evaluate the efficacy and safety of Donepezil in treating the cognitive decline in patients with Parkinson's disease(PD).Methods:Nine literature databases in domestic and abroad were search...
关键词：Parkinson disease Cognitive decline DONEPEZIL META-ANALYSIS 
Donepezil-related inadequate neuromuscular blockade during laparoscopic surgery: A case report
《World Journal of Clinical Cases》2020年第21期5341-5346,共6页Eun-A Jang Tae-Young Kim Eu-Gene Jung Seongtae Jeong Hong-Beom Bae Seongheon Lee 
BACKGROUND Donepezil is an acetylcholinesterase inhibitor used to improve cognition and delay disease progression in dementia patients by increasing acetylcholine levels.This drug may potentially interact with neuromu...
关键词：DONEPEZIL DEMENTIA General anesthesia ROCURONIUM Neuromuscular blocking agents Case report 
Efficacy and safety of traditional Chinese medicine kidney-nourishing formula for Alzheimer's disease in comparison with donepezil:a systematic review and meta-analysis被引量：1
《Traditional Medicine Research》2020年第5期337-354,共18页Fei-Zhou Li Yi-Ni Zhang Tong Zhang Ling Liu Ping Wang 
National Natural Science Foundation of China(No.81573865).
Objective:Finding an effective therapy against Alzheimer’s disease(AD)has been associate increasingly pressing issue and traditional Chinese medicine(TCM)is widespread in the prevention and treatment of AD in China.T...
关键词：Alzheimer's disease Traditional Chinese medicine Kidney-nourishing formula DONEPEZIL Systematic review META-ANALYSIS 
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