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相关机构：环境与疾病相关基因教育部重点实验室西安交通大学空军军医大学（第四军医大学）香港浸会大学更多>>
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Reduced Firing of Nucleus Accumbens Parvalbumin Interneurons Impairs Risk Avoidance in DISC1 Transgenic Mice被引量：1
《Neuroscience Bulletin》2021年第9期1325-1338,共14页Xinyi Zhou Bifeng Wu Wenhao Liu Qian Xiao Wei He Ying Zhou Pengfei Wei Xu Zhang Yue Liu Jie Wang Jufang He Zhigang Zhang Weidong Li Liping Wang Jie Tu 
This work was supported by the National Natural Science Foundation of China(31671116,31761163005,31800881,and 91132306);the International Big Science Program Cultivation Project of Chinese Academy of Sciences(172644KYS820170004);the External Cooperation Program of the Chinese Academy of Sciences(172644KYSB20160057);Science and Technology Program of Guangzhou Municipality(202007030001);the Key-Area Research and Development Program of Guangdong Province(2018B030331001 and 2018B03033600);Shenzhen Government Basic Research Grants(JCYJ20200109115405930 and JCYJ20200109150717745).
A strong animal survival instinct is to approach objects and situations that are of benefit and to avoid risk.In humans,a large proportion of mental disorders are accompanied by impairments in risk avoidance.One of th...
关键词：DISC1 Risk avoidance PARVALBUMIN Nucleus accumbens 
Modulation of firing activity by endogenous GABA_A receptors in the globus pallidus of MPTP-treated parkinsonian mice被引量：1
《Neuroscience Bulletin》2013年第6期701-707,共7页Xin-Yi Chen Yan Xue Hua Wang Su-Hong Zhu Xiao-Meng Hao Lei Chen 
supported by the National Natural Science Foundation of China(31070942,81200872);a grant from the Undergraduate Science and Technology Innovation Foundation in Shandong University,Shandong Province,China(2011475)
The globus pallidus in rodents,equivalent to the external segment of the globus pallidus in primates,plays an important role in movement regulation.Previous studies have shown abundant γ-aminobutyric acid（GABA）ergi...
关键词：globus pallidus GABA A receptor Parkinson’s disease single unit recording 
Firing activity of locus coeruleus noradrenergic neurons increases in a rodent model of Parkinsonism被引量：1
《Neuroscience Bulletin》2009年第1期15-20,共6页王涛 张巧俊 刘健 吴仲恒 王爽 
supported by the Foundation of Science and Technological Program of Shaanxi Province,China (No. 2007K15-G1).
Objective To investigate the changes in the firing activity of noradrenergic neurons in the locus coeruleus (LC) in a rat model of Parkinson disease (PD). Methods 2 and 4 weeks after unilateral lesion of the nigrostri...
关键词：locus coeruleus 6-HYDROXYDOPAMINE Parkinson disease ELECTROPHYSIOLOGY 
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