云南高校图书馆联盟文献共享服务平台- 6-HYDROXYDOPAMINE

6-HYDROXYDOPAMINE: 作品数：72被引量：186H指数：6; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：王凤忠范蓓吴蔚然朱子涛李博为更多>>; 相关机构：中国农业科学院农产品加工研究所西南医科大学附属中医医院第四军医大学环境与疾病相关基因教育部重点实验室更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划河北省自然科学基金更多>>

Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson’s disease: 《Neural Regeneration Research》2025年第2期574-586,共13页Olivier Kerdiles Méryl-Farelle Oye Mintsa Mi-mba Katherine Coulombe Cyntia Tremblay VincentÉmond Martine Saint-Pierre Clémence Rouxel Line Berthiaume Pierre Julien Francesca Cicchetti Frédéric Calon; supported by funding from Parkinson Canada;funded by a scholarship from Parkinson Canada;a scholarship from Fonds d’Enseignement et de Recherche (FER) (Faculty of Pharmacy, Université Laval); There is a need to develop interventions to slow or reverse the degeneration of dopamine neurons in Parkinson’s disease after diagnosis.Given that preclinical and clinical studies suggest benefits of dietary n-3 poly...; 关键词：6-HYDROXYDOPAMINE DOPAMINE dopamine transporter EXERCISE neurorestoration Parkinson’s disease polyunsaturated fatty acids omega-3

Neurobehavioral Analysis of Ethanolic Extract of Roots and Rhizomes of Acorus calamus in 6-hydroxydopamine Hydrobromide-induced ADHD Neonatal Rat Model——An Observational Study: 《World Journal of Traditional Chinese Medicine》2024年第3期316-321,共6页Mariyappan Kousalya Palayyan Muralidharan Hanish Singh Jayasingh Chellammal; Background: An imbalance in Nor-adrenaline and Dopamine neurotransmitter levels in the brain is the reason for the development of Attention Deficit Hyperactivity Disorder(ADHD) which is a neurodevelopmental disorder. ...; 关键词：6-Hydroxy dopamine INTRACEREBROVENTRICULAR anxiety cognitive HYPERACTIVITY

Single-neuron neurodegeneration as a degenerative model for Parkinson’s disease被引量：2: 《Neural Regeneration Research》2024年第3期529-535,共7页Sandro Huenchuguala Juan Segura-Aguilar; The positive effect of levodopa in the treatment of Parkinson’s disease,although it is limited in time and has severe side effects,has encouraged the scientific community to look for new drugs that can stop the neuro...; 关键词：1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine 6-HYDROXYDOPAMINE aminochrome dopaminergic neurons DT-diaphorase exogenous neurotoxins glutathione transferase M2-2

Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson’s disease and neuronal damage through inhibition of microglia被引量：8: 《Neural Regeneration Research》2023年第10期2291-2300,共10页Zhong-Xia Zhang Yong-Jie Zhou Ping Gu Wei Zhao Hong-Xu Chen Ruo-Yu Wu Lu-Yang Zhou Qing-Zhuo Cui Shao-Kang Sun Lin-Qi Zhang Ke Zhang Hong-Jun Xu Xi-Qing Chai Sheng-Jun An; supported by the Natural Science Foundation of Hebei Province,Nos.18967728D (to XQC),H2021423063 (to HXC);Youth Top Talent Project of Colleges and Universities in Hebei Province,No.BJ2021033 (to HXC)。; Microglia-mediated inflammatory responses have been shown to play a crucial role in Parkinson’s disease. In addition, exosomes derived from mesenchymal stem cells have shown anti-inflammatory effects in the treatment...; 关键词：6-HYDROXYDOPAMINE dopamine neurons EXOSOMES inflammation mesenchymal stem cells MICROGLIA Parkinson’s disease PYROPTOSIS

Single-nuclei RNA sequencing uncovers heterogenous transcriptional signatures in Parkinson's disease associated with nuclear receptor-related factor 1 defect被引量：2: 《Neural Regeneration Research》2023年第9期2037-2046,共10页Piniel Alphayo Kambey Wen-Ya Liu Jiao Wu Bakwatanisa Bosco Iqra Nadeem Kouminin Kanwore Dian-Shuai Gao; supported by the National Natural Science Foundation of China,No. 81971006 (to DSG)。; Previous studies have found that deficiency in nuclear receptor-related factor 1(Nurr1),which participates in the development,differentiation,survival,and degeneration of dopaminergic neurons,is associated with Parkin...; 关键词：6-HYDROXYDOPAMINE dopaminergic neurons dopamine transporter nuclear receptor-related factor 1 Parkinson’s disease proteomics analysis Seurat clustering single-nuclei RNA sequencing substantia nigra tyrosine hydroxylase

The transient receptor potential melastatin 2:a new therapeutical target for Parkinson's disease?被引量：4: 《Neural Regeneration Research》2023年第8期1652-1656,共5页Ana Flávia F.Ferreira Luiz Roberto G.Britto; funded by Coordination for the Improvement of Higher Education Personnel (CAPES,Brazil-Finance Code 001,to LRB);the S?o Paulo Research Foundation(FAPESP,Brazil,project#2018/07366-4);The National Council for Scientific and Technological Development (CNPq,Brazil,project#303006/2018-8,to LRB);a PhD fellowship from FAPESP under Grant Agreement No 2020/02109-3。; The transient receptor potential melastatin 2 is a calcium-permeable cation channel member of the TRP family. Also known as an oxidative stress-activated channel, the transient receptor potential melastatin 2 gating m...; 关键词：1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine(MPTP) 1-methyl-4-phenylpyridinium(MPP+) 6-HYDROXYDOPAMINE AG490 CLOTRIMAZOLE flufenamic acid N-(p-amylcinnamoyl)anthranilic acid Parkinson's disease poly-ADPR polymerase type 1(PARP1) ROTENONE PARAQUAT transient receptor potential melastatin 2(TRPM2)

8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases被引量：1: 《Acta Pharmaceutica Sinica B》2023年第5期2152-2175,共24页Damijan Knez Daniel Diez-Iriepa Mourad Chioua Andrea Gottinger Milica Denic Fabien Chantegreil Florian Nachon Xavier Brazzolotto Anna Skrzypczak-Wiercioch Ane Meden Anja Pilar Janko Kos Simon akelj Jure Stojan Kinga Saat Julia Serrano Ana Patricia Fernández Aitana Sánchez-García Ricardo Martínez-Murillo Claudia Binda Francisco López-Muoz Stanislav Gobec JoséMarco-Contelles; MINECO(Government of Spain,grant number SAF-2015-65586-R);UCJC(grants"OPTICOMC903"and"NACONT")to JMC;ARRS(Slovenian Research Agency)core research funding P1-0208,P4-0127 and P1-0189,and project Z1-1859;Italian Ministry of Education,University and Research(MIUR,"Dipartimenti di Eccellenza Program 2018-2022-Dept.of Biology and Biotechnology L.Spallanzani",University of Pavia,Italy);the French Ministry of Armed Forces(Direction Générale des Armées and Service de Santédes Armées,France)under grant number NBC-5-C-4210。; We describe the development of quinolylnitrones(QNs)as multifunctional ligands inhibiting cholinesterases(ChEs:acetylcholinesterase and butyrylcholinesterase—h BChE)and monoamine oxidases(hMAO-A/B)for the therapy of ...; 关键词：Quinolylnitrone BUTYRYLCHOLINESTERASE Monoamine oxidase B Alzheimer's disease Multifunctional ligands 6-Hydroxydopamine model Passive avoidance task Novel object recognition

Neuroprotective effects of insulin-like growth factor-2 in 6-hydroxydopamine-induced cellular and mouse models of Parkinson’s disease被引量：3: 《Neural Regeneration Research》2023年第5期1099-1106,共8页Hai-Ying Zhang Yong-Cheng Jiang Jun-Rui Li Jia-Nan Yan Xin-Jue Wang Jia-Bing Shen Kai-Fu Ke Xiao-Su Gu; supported by the National Natural Science Foundation of China,Nos. 81873742 (to KFK), 81901195 (to JBS);Nantong Technology Project,Nos. JC2020052 (to XSG),JCZ19087 (to XSG)。; Skin-derived precursor Schwann cells have been reported to play a protective role in the central nervous system. The neuroprotective effects of skin-derived precursor Schwann cells may be attributable to the release o...; 关键词：6-HYDROXYDOPAMINE ALPHA-SYNUCLEIN insulin-like growth factor-2 receptor insulin-like growth factor-2 NEURODEGENERATION NEUROPROTECTION Parkinson’s disease skin-derived precursor Schwann cells

基于文献数据库的6-OHDA帕金森病大鼠模型特点分析及在中药研究中的应用被引量：5: 《中国比较医学杂志》2023年第1期93-102,共10页王孟迪张秋梅范蓓 Alberto Carlos Pires Dias 王凤忠王琼; 国家高端外国专家引进计划(G2022051012L);(泸州-医科大)应用基础研究项目(2018LZXNYD-ZK32);四川省国际科技创新合作/港澳台科技创新合作项目(2019YFH0023)。; 目的分析6-OHDA诱导的大鼠PD模型的品系选择、性别、造模要素、模型评价方法以及在抗PD中药研究中的应用情况,以期为6-OHDA模型在帕金森研究中的应用提供参考。方法查阅近20年来中国知网(CNKI)和PubMed中应用6-OHDA建立PD大鼠模型的相...; 关键词：帕金森病大鼠 6-羟基多巴胺(6-hydroxydopamine 6-OHDA) 中药

Humulus japonicus extract alleviates oxidative stress and apoptosis in 6-hydroxydopamine-induced PC12 cells被引量：2: 《Asian Pacific Journal of Tropical Biomedicine》2022年第5期197-206,共10页Feng Wang Byoung Ok Cho Jae Young Shin Suping Hao Seon Il Jang; financially supported by the Ministry of Small and Medium Enterprise and Startups (MSS),Korea,under the Social Economy Innovation Growth Project (R&D)(Project number P0013037); Objective:To explore the possible neuroprotective activities of Humulus japonicus extract against Parkinson's disease(PD)in a cellular model.Methods:PD was modeled in PC12 cells using 6-hydroxydopamine(6-OHDA).The cel...; 关键词：Humulus japonicus Parkinson’s disease Oxidative stress APOPTOSIS MAPK PC12 cells Nrf2

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