FRIZZLED

作品数：70被引量：296H指数：9
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相关领域：医药卫生生物学更多>>
相关作者：赵成海王进卜献民张宁庄立岩更多>>
相关机构：中国医科大学南方医科大学上海海洋大学东南大学更多>>
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相关基金：国家自然科学基金辽宁省自然科学基金云南省应用基础研究基金湖北省自然科学基金更多>>
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Skeletal phenotypes in secreted frizzled-related protein 4 gene knockout mice mimic skeletal architectural abnormalities in subjects with Pyle's disease from SFRP4 mutations被引量：1
《Bone Research》2023年第1期193-200,共8页Robert Brommage Jeff Liu David R.Powell 
supported by Lexicon Pharmaceuticals。
Mutations in SFRP4 cause Pyle’s bone disease with wide metaphyses and increased skeletal fragility.The WNT signaling pathway plays important roles in determining skeletal architecture and SFRP4 is a secreted Frizzled...
关键词：SFRP4 SKELETAL elevated 
Secreted frizzled related-protein 2(Sfrp2)deficiency decreases adult skeletal stem cell function in mice
《Bone Research》2021年第4期606-617,共12页Luis Fernandez de Castro Brian丄Sworder Byron Mui Kathryn Futrega Agnes Berendsen Matthew D.Phillips Nathan J.Burbach Natasha Cherman Sergei Kuznetsov Yankel Gabet Kenn Holmbeck Pamela G.Robey 
This research was supported by the Division of Intramural Research,National Institute of Dental and Craniofacial Research,a part of the Intramural Research Program of the National Institutes of Health,Department of Health and Human Services.Open Access funding provided by the National Institutes of Health(NIH).
In a previous transcriptomic study of human bone marrow stromal cells(BMSCs,also known as bone marrow-derived^mesenchymal stem cells#,)/SFRP2 was highly over-represented in a subset of multipotent BMSCs(skeletal stem ...
关键词：SKELETAL impaired healing 
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