云南高校图书馆联盟文献共享服务平台- FRIZZLED

FRIZZLED: 作品数：70被引量：297H指数：9; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：赵成海王进卜献民张宁庄立岩更多>>; 相关机构：中国医科大学南方医科大学上海海洋大学东南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金辽宁省自然科学基金云南省应用基础研究基金湖北省自然科学基金更多>>

Peptide Cy_(RL-QN15)accelerates hair regeneration in diabetic mice by binding to the Frizzled-7 receptor: 《Zoological Research》2024年第6期1287-1299,共13页Yu-Tong Wu Ze-Qiong Ru Ying Peng Zhe Fu Qiu-Ye Jia Zi-Jian Kang Yuan-Sheng Li Yu-Bing Huang Sai-Ge Yin Kun Guo Nai-Xin Liu Cheng-An Feng Jing Tang Bai-Yu Zhang Zhi Yang Ying Wang Xin-Wang Yang; supported by the Key Program of Yunnan Applied Basic Research Project(202301AS070036);Outstanding Youth Program of Yunnan Applied Basic Research Project-Kunming Medical University Union Foundation(202301AY070001-301);First-Class Discipline Team of Skin&Mucosal Regenerative Medicine of Kunming Medical University(2024XKTDTS10);National Natural Science Foundation of China(32360138,32301054,32060212,82371567);Program of Yunnan Applied Basic Research Project-Kunming Medical University Union Foundation(202301AY070001-012,202101AY070001-006,202301AY070001-198,202101AY070001-035,202101AY070001-036,202401AY070001-028,202401AY070001-068)。; Individuals with diabetes frequently face serious challenges,including delayed wound healing and increased risk of infection.Notably,the regeneration of hair follicles plays a crucial role in accelerating diabetic ski...; 关键词：CyRL-QN15 Hair follicle stem cells(HFSCs) Β-CATENIN Frizzled-7

Retraction:MicroRNA-520b suppresses proliferation,migration,and invasion of spinal osteosarcoma cells via downregulation of frizzled-8: 《Oncology Research》2024年第10期1687-1687,共1页Oncology Research Editorial Office; Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in man...; 关键词：raised INVASION concerned

Secreted Frizzled-Related Protein 5 Mediates Wnt5a Expression in Microcystin-Leucine-Arginine-Induced Liver Lipid Metabolism Disorder in Mice: 《Biomedical and Environmental Sciences》2024年第8期850-864,共15页Meiyan Yang Furong Yu Qianqian Ji Huiying Zhang Jiaxiang Zhang Daojun Chen; supported by the Natural Science Research Project of colleges and Universities in Anhui Province[2022AH052336];High Level Talent Research Initiation Fund Of Anhui Medical College[2023RC004]。; Objective Microcystin-leucine-arginine(MC-LR)exposure induces lipid metabolism disorders in the liver.Secreted frizzled-related protein 5(SFRP5)is a natural antagonist of winglesstype MMTV integration site family,memb...; 关键词：Jun N-terminal kinase Secreted frizzled-related protein 5 WNT5A Hepatic lipid metabolism disorder

Wnt5a-Frizzled-2通路与缺血再灌注损伤的研究现状: 《中国临床药理学杂志》2024年第13期1972-1976,共5页孙志鹏董树素马川程王琛莹陈飞王海英; 国家自然科学基金青年基金资助项目(81703490);山东省医药卫生科技发展计划基金资助项目(202002061311);济宁医学院教师科研扶持基金资助项目(JYFC2019KJ013);济宁医学院大学生创新训练计划基金资助项目(cx2021140)。; Wnt信号通路包括经典通路和非经典通路,Wnt5a-Frizzled-2通路参与非经典通路中的Wnt/Ca^(2+)信号通路,该通路由Wnt相关蛋白Wnt5a与其配体Frizzled-2结合后被激活,可调控细胞中的部分关键位点影响细胞的信号转导,且与细胞的生长进程密切...; 关键词：Wnt5a-跨膜蛋白受体2通路细胞凋亡细胞自噬缺血再灌注损伤

微小RNA-30a-5p抑制胃癌增殖与侵袭的机制被引量：2: 《中华实验外科杂志》2023年第10期2008-2011,共4页黄海李燕彬王凯刘静郭志远于方璞李玉明; 山东省自然科学基金面上项目(ZR2019MH080);滨州医学院校级课题(BY2022KJ17)。; 目的探讨人微小RNA(has-miR)-30a-5p调控Frizzled 2(FZD2)基因激活Wnt/β-连环蛋白(β-catenin)信号通路对胃癌细胞增殖及侵袭的作用机制。方法体外培养胃癌MKN-45细胞;在胃癌细胞系中使用小干扰RNA(siRNA)转染建立微小RNA(miR)-30a-5p...; 关键词：胃癌微小RNA Frizzled 2 Wnt/β-连环蛋白

Study on the Correlation Between SFRP-5 Expression Level, Insulin Resistance, and Glycolipid Metabolism in Gestational Diabetes Mellitus: 《Journal of Clinical and Nursing Research》2023年第2期53-58,共6页Bei Wang Chenyuan Cao Rui Li Yan An Fang Wang Yuxiang Huang Jinjin Qin; Youth Science and Technology Fund of Affiliated Hospital of Hebei University(Project number:2017Q024);Baoding City Science and Technology Plan Projects(Project number:2041ZF295);Hebei University Medical Subject Cultivation Project(Project number:2022B03)。; Objective:To investigate the correlation between serum secretory frizzled-related protein 5(SFRP-5)expression levels and insulin resistance and glucolipid metabolism in patients with gestational diabetes mellitus(GDM)...; 关键词：Gestational diabetes mellitus Secretory frizzled-related protein 5 Insulin resistance Glucolipid metabolism

Skeletal phenotypes in secreted frizzled-related protein 4 gene knockout mice mimic skeletal architectural abnormalities in subjects with Pyle's disease from SFRP4 mutations被引量：1: 《Bone Research》2023年第1期193-200,共8页Robert Brommage Jeff Liu David R.Powell; supported by Lexicon Pharmaceuticals。; Mutations in SFRP4 cause Pyle’s bone disease with wide metaphyses and increased skeletal fragility.The WNT signaling pathway plays important roles in determining skeletal architecture and SFRP4 is a secreted Frizzled...; 关键词：SFRP4 SKELETAL elevated

Identifification of Therapeutic Targets and Prognostic Biomarkers Among Frizzled Family Genes in Glioma被引量：1: 《IMP & HIRFL Annual Report》2022年第1期163-163,共1页Xie Yi Zhang Hong Li Qiang; The biological functions of the frizzled gene family(FZDs),as the key node of wingless-type MMTV integra-tion site family(Wnt)and mammalian target of rapamycin signaling pathways,have not been fully elucidated in glio...; 关键词：SURVIVAL GLIOMA CANCER

miR-99a-5p inhibits target gene FZD5 expression and steroid hormone secretion from goat ovarian granulosa cells被引量：4: 《Journal of Integrative Agriculture》2022年第4期1137-1145,共9页ZHU Lu JING Jing QIN Shuai-qi LU Jia-ni ZHU Cui-yun ZHENG Qi LIU Ya FANG Fu-gui LI Yun-sheng ZHANG Yun-hai LING Ying-hui; supported by the National Natural Science Foundation of China(31772566 and 31972629);the Central Guidance on Local Science and Technology Development Fund of Anhui Province,China(202007d06020005)。; MicroRNA(miRNA) has vital regulatory effects on the proliferation, differentiation and secretion of ovarian granulosa cells, but the role of miR-99a-5p in goat ovarian granulosa cells(GCs) is unclear. Both miR-99a-5p ...; 关键词：miRNA Frizzled-5 follicular development ESTRADIOL PROGESTERONE

黄蒲通窍胶囊对阿尔茨海默病模型大鼠Wnt/Ca^(2+)信号通路的影响被引量：4: 《安徽中医药大学学报》2022年第1期73-78,共6页刘娟叶树谢道俊王艳蔡标; 国家自然科学基金项目(81873351);安徽省自然科学基金项目(1908085J27);安徽高校自然科学研究项目(KJ2020A0439)。; 目的观察黄蒲通窍胶囊对阿尔茨海默病(Alzheimer's disease,AD)模型大鼠学习记忆的影响,探究其潜在作用机制。方法将30只SD大鼠随机分为空白组、模型组、黄蒲通窍胶囊组,每组10只,腹腔注射D-半乳糖联合双侧海马注射Aβ_(25-35)复制AD大...; 关键词：Wnt5 FRIZZLED PLCβ 黄蒲通窍胶囊阿尔茨海默病

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