PROGESTERONE

作品数：264被引量：339H指数：8
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相关领域：医药卫生更多>>
相关作者：袁玉英石其贤顾芝萍陈文颖潘俊丽更多>>
相关机构：《中国实用妇科与产科杂志》编辑部中国科学院浙江省医学科学院中国科学院上海生命科学研究院更多>>
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Progesterone Enhances Niraparib Efficacy in Ovarian Cancer by Promoting Palmitoleic-Acid-Mediated Ferroptosis
《Research》2025年第1期230-245,共16页Nayiyuan Wu Xiu Zhang Chao Fang Miaochen Zhu Zhibin Wang Lian Jian Weili Tan Ying Wang He Li Xuemeng Xu Yujuan Zhou Tang-Yuan Chu Jing Wang Qianjin Liao 
supported by the National Natural Science Foundation of China(82003050 and 82173142);Hunan Provincial Natural Science Foundation(2023JJ30375 and 2023JJ60016);Hunan Cancer Hospital Climb Plan(2023NSFC-A004 and 2023NSFC-A003);Changsha Science and Technology Board(kh2201054);Hunan Provincial Health Commission(B2023047708).
Poly(adenosine 5'-diphosphate-ribose)polymerase inhibitors(PARPi)are increasingly important in the treatment of ovarian cancer.However,more than 40%of BRCA1/2-deficient patients do not respond to PARPi,and BRCA wild-t...
关键词：organoid model ovarian cancer niraparib ovarian cancer organoid model ferroptosis 
Progesterone regulates tissue non-specific alkaline phosphatase(TNSALP)expression and activity in ovine utero-placental tissues
《Journal of Animal Science and Biotechnology》2024年第6期2262-2275,共14页Claire Stenhouse Katherine M.Halloran Emily C.Hoskins Robyn M.Moses Guoyao Wu Heewon Seo Gregory A.Johnson Larry J.Suva Dana Gaddy Fuller W.Bazer 
supported by Agriculture and Food Research Initiative Competitive Grant 2016–67015-24958 from the USDA National Institute of Food and Agriculture。
Background Tissue non-specific alkaline phosphatase(TNSALP;encoded by the ALPL gene)has a critical role in the postnatal regulation of p hospliate homeostasis,yet how TNSALP activity and expression are regulated durin...
关键词：Alkaline phosphatase Phosphate PLACENTA Sheep UTERUS 
Exogenous estrogen partially rescues progesterone deficiency and autophagosome enlargement in Mcoln1^(-/-)mouse model with lysosomal storage disorder
《Reproductive and Developmental Medicine》2024年第4期197-205,共9页Zidao Wang Yuehuan Li Christian L.Andersen Ahmed E.El Zowalaty Jonathan M.Hancock Taylor E.Martin Elizabeth W.Howerth Suvitha Viswanathan Haeyeun Byun Xiaoqin Ye 
the Offfce of the Vice President for Research,Interdisciplinary Toxicology Program,and Department of Physiology and Pharmacology at the University of Georgia,and the National Institutes of Health(grants NIH R01HD065939[co-funded by ORWH and NICHD],R03HD097384,and R03 HD100652 to X.Y.)for ffnancial support;Serum P4 and E2 levels were determined at The University of Virginia Center for Research in Reproduction Ligand Assay and Analysis Core,which is supported by the Eunice Kennedy Shriver NICHD/NIH(NCTRI)Grant P50-HD28934.
Objective:FemaleMcoln1^(-/-)mice exhibit progressive progesterone(P4)deficiency,luteal cell degeneration,and premature embryo implantation failure at 5 months old.We attempted to rescue embryo implantation in non-virg...
关键词：TRPML1/Mcoln1 Corpus luteum PROGESTERONE ESTROGEN Heat shock protein 60 Collagen IV Transmission electron microscopy AUTOPHAGOSOME Lipid droplet 
Sandpaper-templated Stretchable Immunosensing Electrodes for Sub-picomolar Progesterone Detection
《Chemical Research in Chinese Universities》2024年第5期874-880,共7页LI Zhaoxian MENG Xingyu FANG Chuyao YI Zhenkai WU Yaoyao LIU Xuanxuan ZHONG Wei ZHANG Limei XIE Zhuang 
supported by the National Natural Science Foundation of China(No.22075325);the Fundamental Research Funds for the Central Universities,Sun Yat-sen University,China(No.23ptpy51).
Female hormone detection,particularly non-invasive monitoring progesterone(P4)levels in body fluids,plays a critical role in female health management and disease diagnosis.However,the challenge still exists because of...
关键词：PROGESTERONE IMMUNOSENSOR Microstructured electrode Stretchable biosensor Electrochemical sensing 
Unraveling the gut-brain axis:the impact of steroid hormones and nutrition on Parkinson's disease被引量：3
《Neural Regeneration Research》2024年第10期2219-2228,共10页Paula Maria Neufeld Ralf A.Nettersheim Veronika Matschke Matthias Vorgerd Sarah Stahlke Carsten Theiss 
This comprehensive review explores the intricate relationship between nutrition,the gut microbiome,steroid hormones,and Parkinson's disease within the context of the gut-brain axis.The gut-brain axis plays a pivotal r...
关键词：diet gut-brain axis microbiome neurodegenerative diseases NUTRITION Parkinson's disease PROGESTERONE steroid hormones 
Beyond reproduction:unraveling the impact of sex hormones on cardiometabolic health被引量：1
《Medical Review》2024年第4期284-300,共17页Viktoria Xega Jun-Li Liu 
supported by NSERC Discovery Grant RGPIN-2017-05246 and CIHR Project Grant PJT-175208 of Canada.
This review thoroughly explores the multifaceted roles of sexual hormones,emphasizing their impact beyond reproductive functions and underscoring their significant influence on cardiometabolic regulation.It analyzes the...
关键词：ESTROGENS PROGESTERONE ANDROGENS metabolic syndrome cardiovascular diseases 
Detection of Progesterone Receptor as a Method of Diagnosing Mammary Cancer in Female Dogs
《Open Journal of Veterinary Medicine》2024年第8期217-227,共11页José de Jesús Vázquez Pérez Angel Ramses Figueroa Hernandez Jorge Peregrina Sandoval Guillermo Nolasco Rodríguez Manuel Rosales Cortés 
Introduction: Canine mammary gland tumor is the most common type of neoplasia in non-ovariectomized bitches. Approximately 50% of tumors are malignant. Neoplasms originating from the mammary gland represent the most c...
关键词：CANCER Mammary Gland PROGESTERONE IMMUNOHISTOCHEMISTRY Progesterone Membrane Receptor Component 1 (PGRMC 1) 
Duphaston as a suitable medication for women taking intracytoplasmic sperm injection to treat infertility
《Reproductive and Developmental Medicine》2024年第2期89-92,共4页Leila Naserpour Katayon Berjis Sanaz Soleymani Moud Rahil Jannatifar 
Objective:Duphaston is used as an alternative to gonadotropin-releasing hormone(GnRH)antagonists for suppressing premature luteinizing hormone(LH)surges.This study aimed to compare the efficacy of Duphaston protocols ...
关键词：Duphaston Cetrotide Progesterone protocol Ovarian hyperstimulation GnRH antagonist 
Effectiveness of Zhenqi Buxue Oral Liquid Combined with Progesterone for Treatment of Oligomenorrhea and Hypomenorrhea with Qi-Blood and Kidney(Shen)Essence Deficiency:A Randomized Controlled Trial被引量：1
《Chinese Journal of Integrative Medicine》2023年第11期963-970,共8页GAN Jing-wen LV De-xin FU Jin SHI Liang-yan YUAN Chun-yan ZENG Xiao-qin LI Jun SUN Ai-jun 
Supported by the Capital’s Funds for Health Improvement and Research(CFH:2020-2-40113);Natural Science Foundation of China(No.82074143);the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.2020-PT320-003)。
Objective:To evaluate the effectiveness and safety of Zhenqi Buxue Oral Liquid(ZQ),progesterone capsules,and their combination in treating oligomenorrhea and hypomenorrhea with qi-blood and Kidney(Shen)essence deficie...
关键词：KIDNEY Blood TREATMENT 
Carbon Chain Length Determines Inhibitory Potency of Perfluoroalkyl Sulfonic Acids on Human Placental 3β-Hydroxysteroid Dehydrogenase 1:Screening,Structure-Activity Relationship,and In Silico Analysis
《Biomedical and Environmental Sciences》2023年第11期1015-1027,共13页TANG Lu Ming MAO Bai Ping ZHANG Bing Ru LI Jing Jing TANG Yun Bing LI Hui Tao GE Ren Shan 
Objective This study aimed to compare 9 perfluoroalkyl sulfonic acids(PFSA)with carbon chain lengths(C4–C12)to inhibit human placental 3β-hydroxysteroid dehydrogenase 1(3β-HSD1),aromatase,and rat 3β-HSD4 activitie...
关键词：3β-hydroxysteroid dehydrogenase 1 Docking analysis Perfluorooctanesulfonic acid PROGESTERONE STRUCTURE-ACTIVITYRELATIONSHIP 
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