Recent studies have shown a link between the consumption of bovine milk and human breast cancer,apparently by agonizing the estrogen receptor(ER),which results in the proliferation of the breast tissues,leading to for...
supported by NSERC Discovery Grant RGPIN-2017-05246 and CIHR Project Grant PJT-175208 of Canada.
This review thoroughly explores the multifaceted roles of sexual hormones,emphasizing their impact beyond reproductive functions and underscoring their significant influence on cardiometabolic regulation.It analyzes the...
Background:Women with uterine leiomyomas may suffer severe symptoms.To avoid risks of side effects,it is necessary to develop an optimal agent to shrink leiomyomas with fewer side effects and a lower recurrence rate.C...
Study on Colloidal Coagulation and Heavy Metal Adsorption Mechanism of Sediment River(No.42007158);Study on the distribution characteristics of birds and the reduction technology of typical pollutants in their habitats in the Yellow River basin(Henan section)(No.23B180008)supported this research.
The intensification of estrogen non-point source pollution has drawn global attention due to their contribution to ecological environment problems worldwide,and it is critical to develop effective,economic and eco-fri...
supported by National Natural Science Foundation of China(No.81671411);Beijing Municipal Administration of Hospitals’Ascent Plan of China(No.DFL20181401).
Menopausal hormone therapy(MHT)is used to treat menopausal complaints including the genitourinary syndrome of menopause,to prevent osteoporosis,and to treat bleeding problems.Since these can be the indications also in...
This study was supported by grants from the National Natural Science Foundation of China(Grant Nos.61673024 and 81971348);the Clinical Medicine Plus X-Young Scholar Project,Peking University,and the Fundamental Research Funds for the Central University(Grant No.PKU2018LCXQ001).
Menopausal hormone therapy(MHT)has been widely used for the clinical treatment of symptoms associated with menopause in women.However,the exact nature of the relationship between MHT and the increased risk of breast c...
supported in part by the National Institutes of Health(NIH;grant numbers:R01 ROl HL70562,HD 105699,and R21 HD097498 to Dong-bao Chen).
Normal pregnancy is associated with dramatically increased estrogen biosynthesis whose role is believed to raise uterine blood flow to facilitate the bi-directional maternal-fetal exchanges of gases(O_(2) and CO_(2)),...
There is increasing attention about managing the adverse effects of adjuvant therapy(Chemotherapy and anti-estrogen treatment)for breast cancer survivors(BCSs).Vulvovaginal atrophy(VVA),caused by decreased levels of c...
Alzheimer’s disease(AD)is a progressive neurodegenerative condition that goes f rom mild cogni t ive impai rment in prodromal disease to severely disabling deficits in advanced stages.The risk for AD development,as w...
This research was funded by an Australian Research Council Linkage grant(LP0560600)with industry partner Veolia;the New Zealand Ministry of Business,Innovation and Employment(MBIE C03X0902).
There has been much effort to assess the efficacy of sewage treatment plants to remove chemicals with estrogenic activity,but other modes of toxicity have received less attention.This study assessed the efficacy of ad...