supported by the National Natural Science Foundation of China(Nos.U2267221,22107029,22377135);the Bohai Rim Advanced Research Institute for Drug Discovery(No.LX215002);the Natural Science Foundation of Shandong Province(No.ZR2022QH212);the Taishan Scholars Program(No.tsqn202312305);the Young Elite Scientists Sponsorship Program by Chinese Chemical Society;the Fundamental Research Projects of Science&Technology Innovation and development Plan in Yantai City(No.2023JCYJ059);the Shandong Laboratory Program(No.SYS202205);the Shanghai Postdoctoral Excellence Program(No.2023704)。
Fluorescence lateral flow immunoassay(LFA)has emerged as a powerful tool for rapid screening of various biomarkers owing to its simplicity,sensitivity and flexibility.It is noteworthy that fluorescent probe mainly det...
supported by the National Natural Science Foundation of China(No.22075325);the Fundamental Research Funds for the Central Universities,Sun Yat-sen University,China(No.23ptpy51).
Female hormone detection,particularly non-invasive monitoring progesterone(P4)levels in body fluids,plays a critical role in female health management and disease diagnosis.However,the challenge still exists because of...
The authors acknowledge financial support from the National Natural Science Foundation of China(Grant Nos.62001460,31971368,12202461,and 22104148);the Guangdong Regional Joint Funds for Young Scientists(Grant Nos.2020A1515110201 and 2020A1515110368);Guangdong Provincial General Funding(Grant No.2021A1515220156);Guangdong Basic and Applied Basic Research Funding-Regional Joint Fund(Grant No.2020B1515120040);Shenzhen Science and Technology Research Funding(Grant Nos.JSGG20201103153801005,JSGG20191115141601721,ZDSYS20220527171406014,JCYJ20220818101412027,JCYJ20200109115635440,and JCYJ 20200109115408041).
Sensitive detection and precise quantitation of trace-level crucial biomarkers in a complex sample matrix has become an important area of research.For example,the detection of high-sensitivity cardiac troponin I (hs-c...
supported by the National Key Research and Development Program of China(2023YFF1105002);the Key Project of Guangdong Provincial High School,China(2022ZDZX2004).
4-Chlorophenoxyacetic acid(4-CPA),a synthetic plant regulator,has been banned due to its cumulative toxicity to humans.However,unqualified sampling remains common in the market.To address the poor sensitivity of 4-CPA...
the financial support from the National Natural Science Foundation of China(Nos.21575125 and 21475116);the Natural Science Foundation of Jiangsu Province(Nos.BK20221370 and BK20191434);Key University Natural Science Foundation of Jiangsu-Province(No.20KJA150004);Priority Academic Program Development of Jiangsu Higher Education Institution(PAPD),Project for Science and Technology of Yangzhou(No.YZ2022074);Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX22_3462).
The detection of cytokines plays an important role in clinical diagnosis and immune mechanism research of chicken diseases.In this work,a novel and ultrasensitive chemiluminescent(CL)imaging array immunosensor was pro...
funded by by National Key Research and Development Program of China(2021YFD1800403);National Natural Science Foundation of China(21475116,21575125 and 81302016);Natural Science Foundation of Jiangsu Province(BK20221370,BK20221281);Key University Natural Science Foundation of Jiangsu Province(20KJA150004);the Project for Science and Technology of Yangzhou(YZ2022074,YZ2020076);Crosscooperation project of Subei Peoples’Hospital of Jiangsu Province(SBJC220009);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX21_3203)
Interferon-γis a kind of protein with a wide range of biological activities,which can regulate the immune function of the body,and can be used as an important marker to detect and treat bovine tuberculosis diseases.H...
the National Natural Science Foundation of China (Nos. 22174065, 21974119);the Science and Technology Planning Project of Hunan Province (No. 2020RC_(3)046);Hunan Provincial Natural Science Foundation of China (No.2019JJ30020)。
Mulit-enzyme cascades are a major type of chemical transformations and play a crucial role in biological signal transduction and metabolism. Herein, a trienzyme cascade-triggered fluorescent immunosensor platform was ...
The COVID-19 pandemic has posed enormous challenges for existing diagnostic tools to detect and monitor pathogens.Therefore,there is a need to develop point-of-care(POC)devices to perform fast,accurate,and accessible ...
A new design of an immunosensor for viral molecules based on the ISFET nanoscale structure has been proposed. Physical processes take place inimmunosensor are modeled. The effect of modulation of the surface potential...
supported by the National Natural Science Foundation of China(31871875 and 31801626);the Major Instrument Project of the National Natural Science Foundation of China(21927812);the Key Research and Development Program of Hebei Province(21372801D);the 2115 Talent Development Program of China Agricultural University(00109016);the Young Elite Scientist Sponsporship Program by BAST(BYESS2022133)。
The use of immunosensors(IS)as a common biochemical method has been developed rapidly since the middle of the 20th century[1].Due to the specifc complexation between antigens and antibodies for analyte analysis,they p...