Background: Breast cancer is the most common type of cancer among females. Genetic polymorphisms might have a role in carcinogencsis. The aim of this study was to determine whether C to T base substitution within Taq...
Background: Wolf-Hirschhorn syndrome (WHS) is a contiguous gene syndrome that is typically caused by a deletion of the distal portion of the short arm of chromosome 4. However, there are few reports about the featu...
This work was supported by Science Foundation of China grants from the National Natural (No. 30971259), the 15th Military Project for Tackling Key Problems in Science and Technology of China (No. 07CX306), and the Scientific and Technological Innovation Fund for Young Investigation, General Hospital of People's Liberation Army (No. 09KMM23).
Background Patients with the genotypes of both CYP2C9*3/*3 and VKORC1-1639 A/A are expected to require the lowest dose of warfarin, and to have a greatly increased risk of bleeding. The experience for the dosing of ...
Background The genetic variations in VKORC1 modulate the stable responses to warfarin administration. But the role of VKORC1 polymorphisms during the initial anticoagulation and elimination period in the Hart Chinese ...
Background Almost half of the world’s population suffer from the Helicobacter pylori (H. pylori) infection, but only some individuals develop gastric diseases with clinical symptoms. One reason for the phenomenon may...
Objective To develop a simple,cheap,quick,accurate and practical method for a high throughout genotypes assay of human papillomavirus (HPV) DNA. Methods Crude DNA was extracted by a simplified proteinase K digesting...
ThisstudywassupportedbygrantsfromZhejiangProvincialHealthBureauFundation (No .2 0 0 0 A0 6 6 )andZhejiangProvincialNaturalScienceFoundationofChina (No .2 0 0 1 30 0 437) .
Objective To investigate the correlation between glutathione S-transferase (GST) M1 and T1 genotypes and endometriosis risk (EM). Methods Polymerase chain reaction (PCR) technique was used to detect the presence or ...
ThisprojectwassupportedbyagrantfromNationalNaturalSciencesFoundationofthePRChina (No 3 9770 683 )
Objective To evaluate the frequencies and polymorphisms of CCR5-△32,CCR2-641 and SDF1-3'A alleles conferring resistance to HIV-1 infection in Chinese population from Han ethnic origin.Methods This cohort was comprise...