the National Key Research and Development Program of China(2017YFC1700200,2017YFC1702000);the National Scientific and Technological Major Projects of China(2017ZX09101004);the National Natural Science Foundation of China(81703604,81773687 and 81573501);Program of Shanghai Academic/Technology Research Leader(18XD1403600);Shuguang Program(No.18SG40);Shanghai Education Development Foundation and Shanghai Municipal Education Commission,Project funded by China Postdoctoral Science Foundation(2017M621520,and 2018T110406).
Esterases participate in the metabolism of^10%of the clinical drugs that contain ester or amide bonds,but the esterases mediated drug/herb-drug interactions(DDIs or HDIs)have not been reviewed in depth.Carboxylesteras...