INTERFERON-Γ

作品数:121被引量:696H指数:13
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Mechanism of simultaneously refolding and purification of proteins by hydrophobic interaction chromatographic unit and applications被引量:2
《Science China Chemistry》2002年第6期655-669,共16页耿信笃 白泉 
This work was supposed by the National Natural ScienceFoundation of China (Grant Nos.39880003 and 20175016).
The hydrophobic amino acid residues of a denatured protein molecule tend to react with the particles of the stationary phase of hydrophobic interaction chromatography (STHIC). These hydrophobic interactions prevent th...
关键词:protein folding mechanism of protein folding quality control hydrophobic interaction Chromatographie unit PURIFICATION biotechnology INTERFERON-Γ 
High expression of synthetic human interferon-γ cDNA in E.coli
《Science China Chemistry》1995年第9期1084-1093,共10页王子轩 杨迪 王启松 李伯良 吕兆海 虞建良 郑宏大 范佩芳 唐建伟 钱民章 郭海鸿 姚曼华 郑仲承 刘新垣 
Human interferon-γ(IFN-γ)cDNA was synthesized,and it makes the usage of favorable codons in E.coli.The authors got 9 different expression plasmids which contain the synthetic IFN-γ-cDNA and have different spaces be...
关键词:IFN-Γ SYNTHETIC GENE high expression. 
A NEW HUMAN INTERFERON-γ MUTANT HARBORING EGF RECEPTOR-INTERFERING SEQUENCE POSSESSES HIGH ANTIPROLIFERATIVE ACTIVITY
《Science China Chemistry》1992年第1期84-91,共8页王晓鸣 李玉英 金奇 张智清 侯云德 
Work supported by China National Expert Committee for Biotechnology Development
An interferon gamma (IFN-γ) mutant gene harboring an additionamal epidermal growth factor (EGF) sequence at its 3’ terminal was constructed and highly expressed in E. coli by using pBV220 as a vector. The new fusion...
关键词:INTERFERON GAMMA EPIDERMAL growth factor protein engineering. 
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