INTERLEUKIN

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Type I interferons promote the survival and proinflammatory properties of transitional B cells in systemic lupus erythematosus patients被引量：12
《Cellular & Molecular Immunology》2019年第4期367-379,共13页Mei Liu Qiang Guo Chunmei Wu Delphine Sterlin Shyamal Goswami Ying Zhang Teng Li Chunde Bao Nan Shen Qiong Fu Xiaoming Zhang 
This work was supported by the National Basic Research Program of China(No.2014CB541904);the National Natural Science Foundation of China(Nos.31470879 81571575 8171101311 and 31770960);the Interdisciplinary Innovation Team,External Cooperation Program(No.GJHZ201312);Key Project QYZDB-SSW-SMC036;the Strategic Priority Research Program(No.XDPB0303),Chinese Academy of Sciences.
A hallmark of systemic lupus erythematosus(SLE)is the breaking of B-cell tolerance with the generation of high-affinity autoantibodies;however,the antibody-independent features of the B-cell compartment in SLE are les...
关键词：Systemic lupus erythematosus type I interferons transitional B cells APOPTOSIS interleukin 6 
Mechanisms underlying the promotion of functional recovery by deferoxamine after spinal cord injury in rats被引量：10
《Neural Regeneration Research》2017年第6期959-968,共10页Jian Hao Bo Li Hui-quan Duan Chen-xi Zhao Yan Zhang Chao Sun Bin Pan Chang Liu Xiao-hong Kong Xue Yao Shi-qing Feng 
supported by the National Natural Science Foundation of China,No.81672171,81330042;the International Cooperation Program of National Natural Science Foundation of China,No.81620108018;a grant from the Ministry of Science and Technology of China,No.2014DFR31210;a grant from the Tianjin Science and Technology Committee of China,No.13RCGFSY19000,14ZCZDSY00044;the Youth Foundation of Tianjin Medical University General Hospital of China,No.ZYYFY2015008
Deferoxamine, a clinically safe drug used for treating iron overload, also repairs spinal cord injury although the mechanism for this action remains unknown. Here, we determined whether deferoxamine was therapeutic in...
关键词：injured interleukin glial caspase saline underlying fibrillary minutes acidic neuronal 
Regulatory B cells in autoimmune diseases被引量：33
《Cellular & Molecular Immunology》2013年第2期122-132,共11页Min Yang Ke Rui Shengjun Wang Liwei Lu 
B cells are generally considered to be positive regulators of the immune response because of their capability to produce antibodies, including autoantibodies. The production of antibodies facilitates optimal CD4＋ T-c...
关键词：autoimmune disease interleukin-lO regulatory B cells 
Granulocyte-macrophage colony-stimulating factor and interleukin 4 induce the malignant transformation of the bone marrow- derived human adult mesenchymal stem cells被引量：5
《Chinese Medical Journal》2011年第5期729-733,共5页ZHOU Xiao-gang YANG Yi YANG Jin-song ZHOU Jian FANG Tao-lin DAI Wen-da CHEN Zheng-rong 
Background The purpose of the study was to examine the effects of granulocyte-macrophage colony-stimulating factor （GM-CSF） and interleukin 4 （IL-4） on the bone-marrow-derived human adult mesenchymal stem cells （...
关键词：bone marrow-derived mesenchymal stem cells malignant transformation interleukin 4 granulocyte-macrophage colony-stimulating factor 
Molecular cloning and expression of interleukin Ibeta (IL-1β) from red seabream (Pagrus major)被引量：2
《Progress in Natural Science:Materials International》2004年第5期396-402,共7页CAIZhonghua SONGLinsheng GAOChunping WULongtao QIULihua 
Supported by the National High-Tech Project (Grant No. 2001AA628180); the Ministry of Science and Technology of China and a Post doctoral Scholarship (Grant No. 20011002110140 ) of K.C. WANG Education Foundation
The interleukin 1β (IL-1β) cDNA was cloned from the red seabream (Pagrus major) by homology cloning strategy. A cDNA fragment was amplified by PCR using two degenerated primers, which were designed according to the ...
关键词：Interleukin-1* homology cloning mRNA expression red seabream. 
Relations of transcription expression of IL-2 with nuclear factor of activated T cells as well as changes of C-Fos and C-Jun after trauma被引量：1
《Chinese Journal of Traumatology》2002年第5期275-278,共4页罗艳 梁华平 胡承香 徐祥 王正国 
ThisworkwassupportedbytheNationalBasic 973ResearchProgramofChina (G19990 5 4 2 03)andtheNationalNaturalScienceFoundationofChina (No .39870 82 8)
Objective: To observe the relations among expression of interleukin 2 (IL 2) in spleen lymphocytes, DNA binding activity of nuclear factor of activated T cells (NFAT) and expression of the partly family members C Fos,...
关键词：Transcription factors Wounds and injuries Interleukin  2 
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