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作品数:569被引量:1187H指数:16
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相关领域:医药卫生更多>>
相关作者:张清宇王海鲲魏玉梅张新时薛佳平更多>>
相关机构:浙江大学中国科学院植物研究所清华大学北京工商大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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  • 期刊=Chinese Chemical Lettersx
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Double stimulus-responsive palladium catalysts for ethylene polymerization and copolymerization
《Chinese Chemical Letters》2024年第7期407-411,共5页Hailong He Wenbing Wang Wenmin Pang Chen Zou Dan Peng 
supported by National Natural Science Foundation of China(No.52203016);China Postdoctoral Science Foundation(Nos.2021M703072 and 2022T150617);USTC Research Funds of the Double First-Class Initiative(No.YD9990002018);The Fundamental Research Funds for the Central Universities(No.WK9990000142)。
The external stimulus response strategy has been evolved rapidly in the field of olefin polymerization.In this work,we modularly synthesized three types of double stimulus responsiveα-diimine palladium catalysts,comb...
关键词:Dual-regulated Stimulus-responsive Palladium Ethylene polymerization Polar monomer 
Asymmetric synthesis of syn-aryl-(2S,3R)-2-chloro-3-hydroxy esters via an engineered ketoreductase-catalyzed dynamic reductive kinetic resolution
《Chinese Chemical Letters》2023年第9期156-159,共4页Xiaoping Yue Yitong Li Di Sang Yuan Tao Zedu Huang Fener Chen 
The National Key Research and Development Program of China(Nos.2021YFA0911400 and 2021YFF0600704);the National Natural Science Foundation of China(Nos.22071033 and 21801047)are acknowledged for the financial supports。
We report here a generic,green synthesis of 17 valuable syn-aryl-(2S,3R)-2–chloro-3–hydroxy esters(syn-(2S,3R)-1)in 73%-99%isolated yields along with 6.1:1–83:1 dr and 31%~>99%ee,through dynamic reductive kinetic r...
关键词:(2S 3R)-2-Chloro-3-hydroxy esters Dynamic reductive kinetic resolution KETOREDUCTASE Directed evolution Asymmetric synthesis 
Targeting self-enhanced ROS-responsive artesunatum prodrug nanoassembly potentiates gemcitabine activity by down-regulating CDA expression in cervical cancer被引量:1
《Chinese Chemical Letters》2023年第7期186-192,共7页Shengtao Wang Kunyi Yu Zhiyu Yu Bingchen Zhang Chaojie Chen Ling Lin Zibo Li Zhongjun Li Yuhua Zheng Zhiqiang Yu 
financial support from Guangdong Nature Resource Center(GDNRC,No.(2020)037);Natural Science Foundation of Guangdong Province(Nos.22019A1515011498,2019A1515011619)。
Prodrug self-delivery carriers with targeting that specifically responded to tumor microenvironments have good potential to improve the application dilemma of approved clinical therapeutic drugs(systemic distribution ...
关键词:ROS self-supplied ROS-responsive Self-delivery carrier Down regulation of CDA Synergistic anti-tumor effect Cervical cancer 
Electroreduction NO to NH_(3)over single metal atom anchored on pyrrole type defective graphene:A DFT study
《Chinese Chemical Letters》2023年第5期571-575,共5页Jiazhi Wang Kai Li Qi Hao Dongxue Liu Xinbo Zhang 
financially supported by the National Natural Science Foundation of China(Nos.21725103,52072362);National Key R&D Program of China(No.2021YFB4000401);Youth Innovation Promotion Association CAS(No.E1202002)。
Electrochemical is considered an attractive approach to recycling the pollution NO(NORR)and producing the valuable NH_(3),which could simultaneously solve the two challenging problems,i.e.,NO removal and NH_(3)synthes...
关键词:DFT calculation Pyrrole-type DESCRIPTOR NORR COHP 
Information encryption with a high information-carrying capacity based on a stimulus-responsive hydrogen-bonded organic framework and a smartphone
《Chinese Chemical Letters》2023年第5期393-396,共4页Tianran Lin Chunsuo Tian Ying Sun Shendong Liu Di Wang Li Hou Shulin Zhao 
financial support from the National Natural Science Foundation(No.22164005);the Natural Science Foundation of Guangxi(No.2022GXNSFAA035475);the Student Innovation Training Program(No.202110602062);the BAGUI Scholar Program。
Information-carrying capacity has become an important factor in the development of encryption and anti-counterfeiting.Herein,a hydrogen-bonded organic framework(HOF-PyTTA)was developed as novel anti-counterfeiting ink...
关键词:Hydrogen-bonded organic framework Fluorescence array SMARTPHONE ANTI-COUNTERFEITING Message encryption 
Biointerface engineering of self-protective bionic nanomissiles for targeted synergistic chemotherapy
《Chinese Chemical Letters》2023年第4期116-121,共6页Xueyan Zhen Linhao Li Lanlan Jia Aihong Zhu Yixuan Yang Sicen Wang Xiaoyu Xie 
supported by the National Natural Science Foundation of China (Nos. 82073807 and 81973277);the WorldClass Universities (Disciplines);the Characteristic Development Guidance Funds for the Central Universities,China (No. PY3A012)。
Erythrocyte membrane(EM)-camouflaged chemotherapeutic delivery nanovehicles hold promise for solid tumor therapy because of their excellent biostability and biocompatibility. However, it is accompanied with insufficie...
关键词:APTAMER Self-protective BIOINTERFACE Targeted drug delivery Synergistic chemotherapy 
ROS-responsive cyclodextrin nanoplatform for combined photodynamic therapy and chemotherapy of cancer被引量:5
《Chinese Chemical Letters》2021年第1期162-167,共6页Die Jia Xianbin Ma Yi Lu Xinyi Li Shengxin Hou Yuan Gao Peng Xue Yuejun Kang Zhigang Xu 
financially supported by the National Natural Science Foundation of China(Nos.51703187,31671037);the Basic and Frontier Research Project of Chongqing(No.cstc2018jcyj AX0104)。
Cyclodextrin(CD) has special spatial structure and well biological safety,so it has been widely used for constructing CD-based na noplatforms.Through functionalization,cyclodextrin can form various stimulusresponse na...
关键词:CHEMOTHERAPY Photodynamic therapy Synergistic therapy Cyclodextrins ROS-responsive 
Synthesis of polypeptide bearing 1,4-dithiane pendants for ROS-responsive drug release被引量:3
《Chinese Chemical Letters》2020年第5期1129-1132,共4页Tianhui Zhang Jiuxu Yao Jiamei Tian Mingxiao Deng Xiuli Zhuang Chunsheng Xiao 
financially supported by National Key Research and Development Program of China(No.2016YFC1100701);the National Natural Science Foundation of China(Nos.51573184,51520105004 and 51833010);the Youth Innovation Promotion Association of Chinese Academy of Sciences(No.2017266)。
Stimuli-re sponsive polypeptides have been intensively investigated fo r controlled drug release,owing to their favorable biocompatibility and biodegradability.In this work,we designed and synthesized a new kind of po...
关键词:Polypeptides ROS-responsive Self-assembly THIOETHER Drug release 
A reactive oxygen species-responsive dendrimer with low cytotoxicity for efficient and targeted gene delivery被引量:6
《Chinese Chemical Letters》2020年第1期275-280,共6页Yueqi Wang Changjian Li Libo Du Yang Liu 
supported by the National Natural Science Foundation of China (Nos.31571020,31570856 and 31300697)
Nonviral vectors have been attracting more attention for several advantages in gene delivery and the development of nonviral gene ca rriers with high delivery efficiency and low cytotoxicity has long been a key projec...
关键词:DENDRIMER Reactive oxygen species Cancer Gene therapy Low cytotoxicity 
Progress on intelligent hydrogels based on RAFT polymerization:Design strategy, fabrication and the applications for controlled drug delivery被引量:5
《Chinese Chemical Letters》2020年第1期19-27,共9页Caihong Xian Qijuan Yuan Ziting Bao Guiting Liu Jun Wu 
supported by National Science and Technology Major Project of the Ministry of Science and Technology of China (No. 2018ZX10301402);International Cooperation and Exchange of the National Natural Science Foundation of China (No. 51820105004);the Science and Technology Program of Guangzhou (No. 201707010094);Guangdong Innovative and Entrepreneurial Research Team Program (Nos. 2013S086 and 2016ZT06S029);the Science and Technology Planning Project of Shenzhen (No. JCYJ20170307141438157)
Although intelligent hydrogels have shown bright potential application in biomedical fields,they were prepared by conventional methods and still face many serious challenges,such as uncontrollable stimulus-response an...
关键词:timulus-responsive HYDROGEL RAFT polymerization Drug controlled release Rapid response 
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