supported in part by National Basic Research Program of China (973 program; 2013CB943103);the National Natural Science Foundation of China (Grant No. 31072029, No.31272439, No. C170104 and No. 31230048);Ph.D. Programs Foundation of Ministry of Education of China (Grant No.20130204110017) for W. Zeng and W Dong;the scholarship from China Scholarship Council (CSC)
Background: Male germline stem cells(MGSCs) are a subpopulation of germ cells in the testis tissue. MGSCs are capable of differentiation into spermatozoa and thus are perfect targets for genomic manipulation to gen...
National Major Projects of the Ministry of Science and Technology of China (Grant No.2012ZX09506001-004)
Overexpression of breast cancer resistance protein (ABCG2/BCRP) in cancer cells may cause tumor resistance to chemotherapeutic drugs. RNA interference (RNAi) can selectively silence the expression of a target gene...