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Observation of Ice-Like Two-Dimensional Flakes on Self-Assembled Protein Monolayer without Nanoconfinement under Ambient Conditions
《Nano-Micro Letters》2025年第8期237-250,共14页Wuxian Peng Linbo Li Xiyue Bai Ping Yi Yu Xie Lejia Wang Wei Du Tao Wang Jian-Qiang Zhong Yuan Li 
supported by the National Natural Science Foundation of China(22273045,52488101 and 22472043);Ningbo Youth Science and Technology Innovation Leading Talent(2023QL041);Tsinghua University Independent Scientific Research Plan for Young Investigator,Tsinghua University Dushi Program,and Initiative Scientific Research Program。
Directly correlating the morphology and composition of interfacial water is vital not only for studying water icing under critical conditions but also for understanding the role of protein–water interac-tions in bio-...
关键词：Self-assembled monolayers 2D ice-like water Water-protein interactions Ice phase transition 
Like a G6-nal:transcriptional control of G-protein coupled receptors during oligodendroglial development
《Neural Regeneration Research》2025年第7期2001-2002,共2页Tim Aberle Michael Wegner 
supported by grants from the Deutsche Forschungsgemeinschaft to MW。
Multilayered control of myelination:Quick,saltatory conduction of action potentials along nerve fibers requires the electrical insulation of axons by myelinating glia.In the central nervous system,this role is taken u...
关键词：gained INSULATION conduction 
甜菜BvNLP2-like基因敲除载体构建与拟南芥中模拟敲除
《中国糖料》2025年第2期20-26,共7页王希 陶艳昵 张西宁 张琦 李志烨 赵春雷 
陇东学院博士基金项目“若干优秀基因资源对植物非生物胁迫耐性作用方式的研究”(XYBYZK2403);博士后研究人员落户黑龙江科研启动资助金“甜菜分子标记开发与重要性状相关标记的筛选”(LBH-Q18108);2017年度黑龙江省省属高等学校基本科研业务费科技创新类重点项目“甜菜分子标记位点库的深度挖掘与候选SSR标记开发”(KJCXZD201713);财政部和农业农村部国家现代农业产业技术体系(糖料)建设项目“甜菜种质资源收集与评价”(CARS-170102)资助。
【目的】为研究此前自甜菜中发现的BvNLP2-like基因的功能,需要观察其过表达与基因敲除对性状的影响。本研究旨在构建该基因的敲除载体,同时构建拟南芥中同源基因敲除载体并进行模拟敲除。【方法】以甜菜BvNLP2-like基因为研究对象,利用...
关键词：甜菜 NLP基因 CRISPR/Cas9 载体构建 基因敲除 
Role of nuclear factor erythroid 2-related factor 2 in negative pressure wound therapy for diabetic foot ulcers
《World Journal of Diabetes》2025年第5期363-373,共11页Hao-Jie Sun Shan-Wen Si Ya-Mei Ma Xue-Kui Liu Hou-Fa Geng Jun Liang 
BACKGROUND Negative pressure wound therapy(NPWT)is a potential treatment for diabetic foot ulcers(DFUs),although the mechanisms underlying its effectiveness remain unclear.This study posits that NPWT may improve wound...
关键词：Negative pressure wound therapy Diabetic foot ulcers Nuclear factor erythroid 2-related factor 2 Kelch-like epichlorohydrin-associated protein 1 HEALING 
Rational construction of enzyme-like stereoselective magnetic chiral nanozymes
《Nano Research》2025年第4期316-324,共9页Xuan Chen Shenli Wang Xiaoxiao Zhang Stefanos Mourdikoudis Chengxiao Song Leung Siu Lun Juan Xie Wing-leung Wong Jorge Perez-Juste Isabel Pastoriza-Santos Kwok-Yin Wong Guangchao Zheng 
the National Natural Science Foundation of China(Nos.22271257,32202063,and 21902148);Natural Science Foundation of Henan(No.232300421096);the National Key R&D Program of China(No.2024YFE0105200);Start-up Research Fundation of Henan University of Technology(No.2021BS053);the Innovation and Technology Commission of Hong Kong,The Hong Kong Polytechnic University;the support from MICIU/AEI/10.13039/501100011033;ERDF/EU(No.PID2022-138724NB-I00);the Xunta de Galicia/ERDF(No.GRC ED431C 2020/09).
Recent studies support that magnetic chiral nanozymes,integrating the features of chirality,magnetism,and enzyme-like catalysis,provide new insights into the synthetic methodologies and applications of chiral nanozyme...
关键词：chiral cobalt superstructures chirality origin solvent effect magnetic circular dichroism enzyme-like stereoselectivity 
The emerging role of mesenchymal stem cell-derived extracellular vesicles to ameliorate hippocampal NLRP3 inflammation induced by binge-like ethanol treatment in adolescence
《Neural Regeneration Research》2025年第4期1153-1163,共11页Susana Mellado María JoséMorillo-Bargues Carla Perpiñá-Clérigues Francisco García-García Victoria Moreno-Manzano Consuelo Guerri María Pascual 
supported by grants from the Spanish Ministry of Health-PNSD(2019-I039 and 2023-I024)(to MP);FEDER/Ministerio de Ciencia e Innovación-Agencia Estatal de Investigación PID2021-1243590B-I100(to VMM);GVA(CIAICO/2021/203)(to MP);the Primary Addiction Care Research Network(RD21/0009/0005)(to MP);a predoctoral fellowship from the Generalitat Valenciana(ACIF/2021/338)(to CPC).
Our previous studies have reported that activation of the NLRP3(NOD-,LRR-and pyrin domain-containing protein 3)-inflammasome complex in ethanol-treated astrocytes and chronic alcohol-fed mice could be associated with ...
关键词：ADOLESCENCE binge-like ethanol treatment extracellular vesicles hippocampus mesenchymal stem cells neuroinflammation NOD- LRR-and pyrin domain-containing protein 3(NLRP3) 
Targeting mixed lineage kinase domain-like protein's nonnecroptosis role:A new horizon in anti-inflammatory therapy for alcoholic liver disease
《World Journal of Gastroenterology》2025年第13期158-162,共5页Yue Xi Dong Guo Shi Li Jie-Yu Guo Xing-Zhen Chen Jing-Feng Tang Ce-Fan Zhou 
Although mixed lineage kinase domain-like protein(MLKL)is widely recognized as a critical effector in the necroptotic signaling pathway,MLKL plays broader regulatory roles beyond programmed necroptosis.Notably,Xuan Yu...
关键词：Mixed lineage kinase domain-like protein ATP-binding pocket CPD4 inhibitor Alcoholic liver disease Therapeutic targets Liver diseases 
Cationic carbon dots:A novel class of mimetic enzymes
《Nano Research》2025年第4期493-515,共23页Xin Wu Zhuang Tong Yunliang Liu Yi Yang Yaxi Li Yuanyuan Cheng Jingwen Yu Naiyun Liu Chanyuan Jin Haitao Li 
supported by the National Natural Science Foundation of China(Nos.52072152,and 51802126);the Jiangsu University Jinshan Professor Fund;the Jiangsu Specially-Appointed Professor Fund;Open Fund from Guangxi Key Laboratory of Electrochemical Energy Materials,Zhenjiang“Jinshan Talents”Project 2021;China PostDoctoral Science Foundation(No.2022M721372);“Doctor of Entrepreneurship and Innovation”in Jiangsu Province(No.JSSCBS20221197);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(Nos.KYCX22_3645 and KYCX24_3964).
Natural enzymes are highly efficient catalysts with strong substrate specificity,making them ideal for biomedical applications.However,they often face issues such as variability,high costs,challenging preparation proc...
关键词：cationic carbon dots enzyme-like CATALYSIS applications NANOMATERIALS 
Read You Like a Book
《小学生时代(大嘴英语)》2025年第4期11-11,共1页邱炯 
Integrating Academic Research Methodologies like Participatory Action Research(PAR)into Design Thinking:A Framework for Group Housing Design
《Journal of World Architecture》2025年第2期117-133,共17页Tadiboina Samantha Kumar Ramesh Srikonda 
The integration of academic research methodologies into design thinking processes presents a transformative approach to addressing complex challenges in group housing,fostering inclusive,sustainable,and user-centered ...
关键词：Design thinking Academic research methodologies Group housing Participatory Action Research(PAR) Co-Design Sustainable housing User-centered design 
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