LTR

作品数：470被引量：927H指数：12
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相关机构：南开大学中国农业科学院哈尔滨兽医研究所东北农业大学浙江农林大学更多>>
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Uncovering novel human gut virome using ultra-deep metagenomic sequencing被引量：1
《Chinese Medical Journal》2022年第20期2395-2397,共3页Harry Cheuk Hay Lau Jun Yu 
Human gastrointestinal tract harbors trillions of commensal microbes including bacteria,viruses,and fungi to form an ecological community,commonly known as the gut microbiome.Being the second most dominant taxonomic k...
关键词：BREAKTHROUGH HARBOR GUT 
Analysis of Serum Metabolic Profile by Ultra-performance Liquid Chromatography-mass Spectrometry for Biomarkers Discovery： Application in a Pilot Study to Discriminate Patients with Tuberculosis被引量：6
《Chinese Medical Journal》2015年第2期159-168,共10页Shuang Feng Yan-Qing Du Li Zhang LeiZhang Ran-Ran Feng Shu-Ye Liu 
Background：Tuberculosis （TB） is a chronic wasting inflammatory disease characterized by multisystem involvement,which can cause metabolic derangements in afflicted patients.Metabolic signatures have been exploited ...
关键词：METABOLITES Orthogonal Partial Least-squares Discriminant Analysis SERUM TUBERCULOSIS Ultra-performance LiquidChromatography-mass Spectrometry 
Histone deacetylase inhibitors inducing human cervical cancer cell apoptosis by decreasin~ DNA-methyltransferase 3B被引量：5
《Chinese Medical Journal》2012年第18期3273-3278,共6页LIU Ning ZHAO Li-jun LI Xiao-ping WANG Jian-liu CHAI Guo-lin WEI Li-hui 
This article was supported by the grants from the National Natural Science Foundation of China，the “985” Project of the Peking University Health Science Center and the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry
Background Histone deacetylase （HDAC） inhibitors are a group of small chemical molecules that inhibit histone deacetylase. At cell level, HDAC inhibitors have multiple biological effects such as cell cycle arrest, a...
关键词：histone deaeetylase inhibitors human cervical cancer apoptosis DNA-methyltransferase 3B Trichostatin A DNA methyl transferase 
Epidermal growth factor receptor-targeted ultra-small superparamagnetic iron oxide particles for magnetic resonance molecular imaging of lung cancer cells in vitro被引量：7
《Chinese Medical Journal》2012年第13期2322-2328,共7页CHEN Chun-li HU Guang-yuan MEI Qi QIU Hong LONG Guo-xian HU Guo-qing 
This study was supported by a grant from the National Natural Science Foundation of China （No. 30470525）.
Background Magnetic resonance （MR） molecular imaging can detect abnormalities associated with disease at the level of cell and molecule. The epidermal growth factor receptor （EGFR） plays an important role in the d...
关键词：ultra-small superparamagnetic iron oxide epidermal growth factor receptor ＂magnetic resonance imaging ＂ target 
Protective effect of O^6-methylguanine-DNA-methyltransferase on mammalian cells被引量：2
《Chinese Medical Journal》2007年第8期714-717,共4页LI Dong-bo WANG Ji-shi FANG Qin SUN Hai-yang XU Wei LI Wei-da 
the grant from the National Natural Science Foundation of China(No.30460127)
Background O^6-methylguanine-DNA-methyltransferase （MGMT） is a specific DNA revising enzyme transferring alkylated groups from DNA to its cysteine residue to avoid the abnormal twisting of DNA. Therefore, it is one ...
关键词：gene therapy drug resistance transfection O^6 -methylguanme-DNA-methyltransferase 
Hybrid retroviral vector with MCK enhancers inserted in LTR for stable and specific expression of human factor IX in skeletal muscle被引量：2
《Chinese Medical Journal》2004年第6期893-898,共6页王健民 侯军 邱信芳 Kurachi Kotoku 薛京伦 
Thisprojectwassupportedin partbyNationalNaturalScienceFoundationofChina (GrantNo 3 93 70 3 2 1)toJW ,StateHighTechnologyDevelopmentProgramofChina (863 Z2 0 0 2 0 1)toJX
Background Retroviral vectors have been widely used to introduce foreign into various target cells in vitro,thus showing relatively high systemic delivery efficiency of various transgene products. The authors investig...
关键词：human factor IX·muscle-specificity·retroviral vectors hybrid·gene expression 
The distribution and significance of renal infiltrating cells in patients with diffuse crescentic glomerulonephritis
《Chinese Medical Journal》2001年第12期35-37,103-104,共5页唐政 吴燕 胡伟新 姚小丹 周红 陈惠萍 刘志红 黎磊石 
Objective To study the significance and distribution of renal infiltrating cells, including monocytes (CD68+ cells), proliferative cell nuclear antigen positive cells (PCNA+ cells), CD4+ and CD8+ cells in diffuse cres...
关键词：CD68  + cells  ·  PCNA  + cells ·  CD8  + cells  ·   crescentic glomerulonephritis 
Apoptosis of infiltrating cells in experimental autoimmune uveoretinitis
《Chinese Medical Journal》2000年第7期67-70,共4页杨培增 周红颜 
ThestudywassupportedbyTrans CenturyOutstandingScientistFoundationofEducationMinistryofChina ;GuangdongProvinceNaturalScienc
To investigate the cellular phenotype and apoptosis of infiltrating cells involved in experimental autoimmune uveoretinitis (EAU) Methods Immunohistochemical staining and in situ apoptosis staining were performed us...
关键词：experimental autoimmune uveoretinitis IMMUNOHISTOCHEMISTRY APOPTOSIS wholemounts technique 
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