supported by the National Key Research and Development program of China(2023YF0913403);the National Natural Science Foundation of China(32200584,31971231);the Fundamental Research Funds for the Central Universities(2042022dx0003,2042022kf1048);the China Postdoctoral Science Foundation(2021M702526).
The minichromosome maintenance complex(MCM)DNA helicase is an important replicative factor during DNA replication.The proper chromatin loading of MCM is a key step to ensure replication initiation during S phase.Becau...