MITOTIC

作品数:61被引量:108H指数:6
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相关领域:生物学医药卫生更多>>
相关作者:张博周平坤黄琼萍朱学良鄢秀敏更多>>
相关机构:沈阳农业大学军事医学科学院北京大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Author Correction: Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration被引量:3
《Cell Research》2021年第3期373-373,共1页Xuan Ming Zhuqiang Zhang Zhuoning Zou Cong Lv Qiang Dong Qixiang He Yangyang Yi Yingfeng Li Hailin Wang Bing Zhu 
This work was also supported by the Ministry of Science and Technology of China(2016YFA0100400);the Chinese Academy of Sciences(XDB39000000 and QYZDY-SSW-SMC031);Z.Z.is sponsored by the Youth Innovation Promotion Association(2017133)of the Chinese Academy of Sciences.
We apologize for the mistake of the fund information in the acknowledgements.The correct information is as follows.This correction does not affect the conclusion of the work.
关键词:Kinetics CORRECTION CONCLUSION 
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration被引量:8
《Cell Research》2020年第11期980-996,共17页Xuan Ming Zhuqiang Zhang Zhuoning Zou Cong Lv Qiang Dong Qixiang He Yangyang Yi Yingfeng Li Hailin Wang Bing Zhu 
This work was primarily supported by the National Natural Science Foundation of China(31530047);This work was also supported by the Ministry of Science and Technology of China(2016YFA0100400);the Chinese Academy of Sciences(XDB39000000 and QYZDYSSW-SMC031);Z.Z.is sponsored by the Youth Innovation Promotion Association(2017133)of the Chinese Academy of Sciences.
Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell identity.Whether DNA methylation pattern in different genomic contexts can all be faithfully maintained is an open question.A ...
关键词:IMPAIRED aging kinetics 
Genome-wide high-resolution mapping of mitotic DNA synthesis sites and common fragile sites by direct sequencing被引量:1
《Cell Research》2020年第11期1009-1023,共15页Fang Ji Hongwei Liao Sheng Pan Liujian Ouyang Fang Jia Zaiyang Fu Fengjiao Zhang Xinwei Geng Xinming Wang Tingting Li Shuangying Liu Madiha Zahra Syeda Haixia Chen Wen Li Zhihua Chen Huahao Shen Songmin Ying 
This work was supported by grants to Songmin Ying from the Ministry of Science and Technology of China(2016YFA0100301);the National Natural Science Foundation of China(81870007,81920108001);the Zhejiang Provincial Natural Science Foundation(LD19H160001);the Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents(2016-63).
Common fragile sites(CFSs)are genomic loci prone to the formation of breaks or gaps on metaphase chromosomes.They are hotspots for chromosome rearrangements and structural variations,which have been extensively implic...
关键词:synthesis RESOLUTION BRIDGING 
Cdk phosphorylation licenses Kif4A chromosome localization required for early mitotic progression被引量:7
《Journal of Molecular Cell Biology》2018年第4期358-370,共13页Zhixiong Dong Changjun Zhu Qimin Zhan Wei Jiang 
This work was supported by CAMS Innovation Fund for Medical Sciences (CIFMS) (2016-12M-1-001), the National Natural Science Foundation of China (31171299, 31271485, and 31301138), the National Basic Research Program of China (2012CB910703), and Tianjin Research Program of Application Foundation and Advanced Technology (12JC2DJC21400). C.Z. is supported by Program for New Century Excellent Talents in University in China (NCET-11-1066).
The chromokinesin Kif4A controls proper chromosome condensation, congression/alignment, and cytokinesis to ensure faithful genetic inheritance. Here, we report that Cdk phosphorylation of human Kif4A at T1161 licenses...
关键词:Kif4A chromokinesin Cdk phosphorylation MITOSIS 
Role of Prosurvival Molecules in the Action of Lidamycin toward Human Tumor Cells
《Biomedical and Environmental Sciences》2009年第3期244-252,共9页A-JING YANG WEI-WEI SHI YONG LI ZHEN WANG RONG-GUANG SHAO DIAN-DONG LI QI-YANG HE 
supported by grants from the National Natural Science Foundation of China (No. 30672482);the National 973 Program (No. 2009CB521807)
Objective Lidamycin, an enediyne antibiotic, leads to apoptosis and mitotic cell death of human tumor cells at high and low concentrations. The reason why tumor cells have distinct responses to lidamycin remains elusi...
关键词:LIDAMYCIN Prosurvival molecules SIRTI deacetylase Apoptosis Mitotic cell death Multidrug resistance 
Fibrillarin redistributes to the spindle poles and partially colocalizes with NuMA during mitosis
《Chinese Science Bulletin》2002年第23期1995-1998,2027-2028,共6页Yan Guo Chaoliang Wei Jinsong Hu Mingxiao Ding Jianguo Chen 
This work was supported by the State Key Basic Research Program of China (Grant No. G1999053906).
Fibrillann, a major protein in the nucleolus. is known to redistribute during mitosis from the nucleolus to the cytosol, and is related to the dynamics of post-mitotic reassembly of the nucleolus. To better understand...
关键词:FIBRILLARIN MITOTIC spindle POLES CENTROSOME NuMA. 
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