云南高校图书馆联盟文献共享服务平台- CENTROSOME

CENTROSOME: 作品数：36被引量：40H指数：3; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：牛瑞芳牛昀韦丽滕俊琳陈建国更多>>; 相关机构：中央研究院天津医科大学北京大学更多>>; 相关期刊：《Chinese Journal of Cancer Research》《Asian Journal of Andrology》《Journal of Integrative Plant Biology》《Microenvironment & Microecology Research》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>

CNKSR2 interactome analysis indicates its association with the centrosome/microtubule system: 《Neural Regeneration Research》2025年第8期2420-2432,共13页Lin Yin Yalan Xu Jie Mu Yu Leng Lei Ma Yu Zheng Ruizhi Li Yin Wang Peifeng Li Hai Zhu Dong Wang Jing Li; supported by the National Nature Science Foundation of China,No.32101020(to JL);the Natural Science Foundation of Shandong Province,Nos.ZR2020MC071(to JL),ZR2023MH327(to HZ);the Integrated Project of Major Research Plan of National Natural Science Foundation of China,No.92249303(to PL);the Natural Science Foundation of Qingdao,No.23-2-1-193-zyyd-jch(to HZ)。; The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding domains.Variants of the CNKS...; 关键词：autism spectrum disorder CENTROSOME CNKSR2 intellectual disability INTERACTOME mass spectrometry MICROTUBULE neurodevelopmental disease protein complexes protein-protein interactions

Four centrosome-related genes to predict the prognosis and drug sensitivity of patients with colon cancer: 《World Journal of Gastrointestinal Oncology》2024年第5期1908-1924,共17页Hui-Yan Wang Yan Diao Pei-Zhu Tan Huan Liang; Supported by Heilongjiang Postdoctoral Fund,No.LBH-Z18214;Haiyan Foundation of Harbin Medical University Cancer Hospital,No.JJQN2014-06;Foundation of Health Commission of Heilongjiang Province,No.2016-096.; BACKGROUND As the primary microtubule organizing center in animal cells,centrosome abnormalities are involved in human colon cancer.AIM To explore the role of centrosome-related genes(CRGs)in colon cancer.METHODS CRGs...; 关键词：Colon cancer CENTROSOME SIGNATURE PROGNOSTIC Immune microenvironment Therapy

Centrosome Defects in Hematological Malignancies: Molecular Mechanisms and Therapeutic Insights: 《Blood Science》2022年第3期143-151,共9页Mingzheng Hu Yijie Wang Jun Zhou; This work was supported by a grant from the National Natural Science Foundation of China(31730050).; Defects in centrosomes are associated with a broad spectrum of hematological malignancies,such as leukemia and lymphoma.Centrosomes in these malignancies display both numerical and structural aberrations,including alt...; 关键词：Centrosome defects Hematological malignancy Cell cycle regulators Cell surveillance pathways Pharmaceutical inhibitors

Control of the Hedgehog pathway by compartmentalized PKA in the primary cilium: 《Science China(Life Sciences)》2022年第3期500-514,共15页Eva Cai Jingyi Zhang Xuecai Ge; supported by the National Institutes of Health(CA235749)。; The Hedgehog(Hh)signaling is one of the essential signaling pathways during embryogenesis and in adults.Hh signal transduction relies on primary cilium,a specialized cell surface organelle viewed as the hub of cell si...; 关键词：Hedgehog signaling protein kinase A(PKA) primary cilium CENTROSOME compartmentalized cell signaling

KIFC1 overexpression promotes prostate cancer cell survival and proliferation in vitro by clustering of amplified centrosomes via interaction with Centrin 2: 《BIOCELL》2021年第5期1369-1391,共23页ANZANA PARVIN BANG-HONG WEI SHUANG-LI HAO WAN-XI YANG FU-QING TAN; Natural Science Foundation of Zhejiang Province,China(No.LY20H040010).; Mitotic kinesin KIFC1 plays critical roles in mitosis by regulating the spindle length,pole formation,and known for clustering extra centrosomes in cancer cells.Centrosome clustering is associated with the survival of...; 关键词：KIFC1 Centrosome clustering Centrosome amplification Prostate cancer

Multifaceted roles of centrosomes in development,health,and disease被引量：2: 《Journal of Molecular Cell Biology》2021年第9期611-621,共11页Feifei Qi Jun Zhou; supported by the National Natural Science Foundation of China(31730050 and 32000481).; The centrosome is a membrane-less organelle consisting of a pair of barrel-shaped centrioles and pericentriolar material and functions as the major microtubule-organizing center and signaling hub in animal cells.The p...; 关键词：CENTROSOME germ cell stem cell IMMUNITY ciliopathy Introduction

Stem cells' centrosomes: How can organelles identified 130 years ago contribute to the future of regenerative medicine?: 《World Journal of Stem Cells》2021年第9期1177-1196,共20页Andreas Goutas Varvara Trachana; At the core of regenerative medicine lies the expectation of repair or replacementof damaged tissues or whole organs. Donor scarcity and transplant rejection aremajor obstacles, and exactly the obstacles that stem cel...; 关键词：CENTROSOME Primary cilium Asymmetry SELF-RENEWAL Differentiation STEMNESS

Centrosome and vascular microenvironmental homeostasis: 《Microenvironment & Microecology Research》2021年第1期12-16,共5页Yang Yang Pei-Pei Liu Ming-Li Li Shu-Ang Li Yi Luan; The homeostasis of vascular microenvironment is essential to maintain the normal vascular structure and function,while its disorder leads to vascular dysfunction,and cardiovascular and cerebrovascular diseases.Centros...; 关键词：VASCULAR MICROENVIRONMENT HOMEOSTASIS CENTROSOME MICROTUBULE Cardiovascular and CEREBROVASCULAR diseases

Centrosome dysfunction:a link between senescence and tumor immunity被引量：2: 《Signal Transduction and Targeted Therapy》2020年第1期1496-1504,共9页Qi Wu Bei Li Le Liu Shengrong Sun Si Sun; supported by National Natural Science Foundation of China(NSFC)Grant No.81471781;National Major Scientific Instruments and Equipment Development Projects Grant No.2012YQ160203 to Dr.Shengrong Sun;supported by National NSFC Grant No.81903166;Hubei Province health and family planning scientific research project Grant No.WJ2019Q044 to Dr.Si Sun.; Centrosome aberrations are hallmarks of human cancers and contribute to the senescence process.Structural and numerical centrosome abnormalities trigger mitotic errors,cellular senescence,cell death,genomic instabilit...; 关键词：IMMUNITY DYSFUNCTION SENESCENCE

Chromosomes and Centrosomes—Team Players in Cell Division: 《Advances in Bioscience and Biotechnology》2020年第1期1-5,共5页Ronald L. Huston; This paper provides a mid-level description of cell division and duplication. The focus is on the roles by the chromosomes, centrosomes, microtubules and the kinetochores. The emphasis is on the mechanical activity an...; 关键词：CHROMOSOME CENTROSOME CENTRIOLE MITOSIS

CENTROSOME