蛋白复合物

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秀丽隐杆线虫RNA结合蛋白复合物AMG-1/SLRP-1通过线粒体稳态维持实现调控生殖腺发育和精子发生
《Science Bulletin》2023年第13期1399-1412,M0004,共15页王鹏 王秋实 陈联万 曹铮 赵海莲 苏瑞宝 王宁 马肖静 单进 陈新艳 张琦 杜宝臣 袁志恒 赵艳梅 张晓荣 郭雪江 薛愿超 苗龙 
supported by the National Natural Science Foundation of China(32270774,31671400,81971439,32070694,31571436,31872822,and 31301153);the National Key Research and Development Program of China(2017YFA0503502,2016YFA0500903,2021YFC2700200,2017YFA0504600,and 2019YFA0508700);funded by the National Institutes of Health Office of Research Infrastructure Programs(P40 OD010440)。
RNA结合蛋白(mtRBP)介导的mRNA转录后调节对精子发生必不可少但却鲜有报道.在本文中,我们鉴定到一个在生殖腺中特异性表达的线粒体RNA结合蛋白AMG-1,它是秀丽隐杆线虫精子发生过程中必需的蛋白,同时与哺乳动物LRPPRC蛋白同源.amg-1突变...
关键词：SPERMATOGENESIS RNA-binding protein mt-rRNA MITOCHONDRIA Caenorhabditis elegans 
Regulation of canonical Wnt/β-catenin pathway in the nucleus
《Chinese Science Bulletin》2014年第28期3530-3535,共6页Wenxiao Han Hongying Wang 
supported by the National Nature Science Foundation of China(81172034)
Canonical Wnt/b-catenin pathway plays a central role in development, homeostasis, as well as tumorigenesis. The regulation of the pathway involves various and complicated mechanisms, including the extracellular, intra...
关键词：细胞核 WNT 蛋白复合物 法规 肿瘤发生 组成部分 监管机构 转录活性 
The putative tumor suppressor C53 interacts with the human telomerase reverse transcriptase hTERT and regulates telomerase activity被引量：4
《Chinese Science Bulletin》2014年第19期2324-2330,共7页Junzhi Zhou Peng Xi Qi Zhou Deqiang Ding Yusheng Cong 
supported by the National Basic Research Program of China(2012CB911203);the National Natural Science Foundation of China(31371398,31071200 and 31171320)
Telomerase is a large ribonucleoprotein complex that contains a catalytic telomerase reverse transcriptase(TERT)and an RNA template.Telomerase activity is tightly controlled by TERT expression,which is regulated at bo...
关键词：人端粒酶逆转录酶 端粒酶活性 亮氨酸拉链结构域 酵母双杂交系统 蛋白复合物 HTERT 相互作用 交互 
Study of the interaction of DNA and histones by spin-stretching and droplet evaporation
《Chinese Science Bulletin》2011年第12期1234-1240,共7页LIU YuYing WANG PengYe DOU ShuoXing ZHANG WeiWei WANG XueJin SANG HongYi 
supported by the National Natural Science Foundation of China (60025516 and 10334100);the Scientific Research Start-up Foundation of China Agricultural University (2009-2-05)
Molecular combing is a powerful and simple method for aligning DNA molecules onto a surface. Using this technique combined with fluorescence microscopy, DNA-histone complexes are stretched on a hydrophobic polymethyl ...
关键词：DNA分子 组蛋白 相互作用 液滴蒸发 拉伸 聚甲基丙烯酸甲酯 蛋白复合物 DNA结合 
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