Eleventh Five-Year Plan for National Science and Technology Major Project (Grant No.2009ZX0930-010);National Science Foundation of China (NSFC81172915);A grant from Major New Drugs Research and Development Platform of Peking University (Grant No.2009ZX09301-010)
Compound YSY-01A, a recently synthesized proteasome inhibitor, has shown potent growth-inhibitory effect on tumor cells in previous researches. However, the mechanism of its inhibitory effects, especially on cell cycl...