supported by the National High-Tech R&D Program of China(“863”Program)(2009AA22704);the National Natural Science Foundation of China(30873089,81173129);the Program for Changjiang Scholars and Innovative Research Team in University(IRT0946);the Open Foundation of Innovative Platform in University of Hunan Province of China(10K078);the Science and Technology Plan Key Grant of Hunan Province of China(2009TP40682);the Fundamental Research Funds for the Central Universities(201023100001)
目的:在细胞水平研究烟酰胺单核苷酸(nicotinamide mononucleotide,NMN)对胰岛素分泌的调节作用及其对与胰岛素分泌相关的重要转录因子胰十二指肠同源盒基因(pancreatic and duodenalhomeobox-1,PDX-1)和分叉头框家族转录因子1(forkhead...