梁毅

作品数:3被引量:8H指数:1
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供职机构:北京大学药学院天然药物学系更多>>
发文主题:HPLC法测定北刘寄奴高效液相色谱法木犀草素芹菜素更多>>
发文领域:医药卫生更多>>
发文期刊:《Journal of Chinese Pharmaceutical Sciences》《药物分析杂志》更多>>
所获基金:国家重点基础研究发展计划更多>>
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On-line HPLC-DAD coupled with ESI-IT-TOF-MS and fluorescence detection to identify DNA-binding compounds from Lithospermum erythrorhizon using acridine orange as the fluorescence probe
《Journal of Chinese Pharmaceutical Sciences》2015年第9期581-590,共10页黄文芳 张藏蔓 李森森 梁毅 王弘 陈世忠 
Peking University Comprehensive Platform for Innovative Drug Research and Development(Grant No.2009ZX--09301--010)
We have developed an on-line detection method using acridine orange as the fluorescence probe and applied this method to rapidly identify active compounds in herbal medicines. This on-line method was equipped with a h...
关键词:ON-LINE Lithospermum erythrorhizon Acridine orange DNA DNA-binding activity 
Two alkaloids as α-amylase inhibitors: enzyme kinetics and molecular modeling investigations
《Journal of Chinese Pharmaceutical Sciences》2015年第2期80-87,共8页梁毅 裴芬 王弘 陈世忠 
State Key Laboratory of Natural and Biomimetic Drugs 2013 Funded Project "Establishment and Application an Online Natural Medicines System with Efficient Separation,Structural Identification and Activity Detection"
In the present study, we studied the inhibitory effects of chelidonine and rutaecarpin on porcine pancreatic a-amylase (PPA) catalyzed hydrolysis using 2-chloro-4-nitrophenyl-4-O-β-D-galactopyranosylmaltoside (Gal...
关键词:α-Amylase inhibitors Kinetic analysis Molecular modeling Chelidonine RUTAECARPINE 
HPLC法测定北刘寄奴中木犀草素和芹菜素的含量被引量:8
《药物分析杂志》2011年第9期1689-1692,共4页林宗涛 梁毅 刘淑娟 陈世忠 王弘 
国家973项目-道地药材的药性特征研究。课题编号:2006CB504707
目的:建立同时测定北刘寄奴中木犀草素和芹菜素含量的HPLC方法。方法:采用Inertsil ODS-3(4.6 mm×150 mm,5μm)色谱柱,以乙腈-0.5%磷酸(28∶72)为流动相,流速1.0 mL.min-1,检测波长340 nm,柱温35℃。结果:木犀草素和芹菜素进样量分别在...
关键词:北刘寄奴 阴行草 木犀草素 芹菜素 含量测定 高效液相色谱法 
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