National Basic Research Program of China(Grant No.2012CB518000);Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20120001110010)
CGRP receptor(CLR) is a B class GPCR that functions only when combined with RAMPs. CLR/RAMP1 has been regarded as a promising target for migraine treatment, as its antagonists have been proved to be effective recent...