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检索条件："关键词=CD4^＋ "
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Impact of baseline CD4^＋ T cell counts on the efficacy of nevirapinebased highly active antiretroviral therapy in Chinese HIV/AIDS patients： a prospective, multicentric study被引量：7
《Chinese Medical Journal》2009年第20期2497-2502,共6页LIU Zheng-yin GUO Fu-ping HAN Yang QIU Zhi-feng ZUO Ling-yan LI Yan-ling LI Tai-sheng 
Background CD4^＋T cell counts have been used as the indicator of human immunodeficiency virus type 1 （HIV-1） disease progression and thereby to determine when to start highly active antiretroviral therapy （HAART）...
关键词：human immunodeficiency virus acquired immunodeficiency syndrome highly active antiretroviral therapy CD4^＋ T cell counts NEVIRAPINE 
I L- 15 trans-presentation regulates homeostasis of CD4^＋ T lymphocytes
《Cellular & Molecular Immunology》2014年第4期387-395,共9页Xi-Lin Chen Diwakar Bobbala Yuneivy Cepero Donates Marian Mayhue Subburaj Ilangumaran Sheela Ramanathan 
Interleukin-15 （IL-15） is essential for the survival of memory CD8^＋ and CD4^＋ T cell subsets, and natural killer and natural killer T cells. Here, we describe a hitherto unreported role of IL-15 in regulating hom...
关键词：BDC2.5 CD4^＋ T cells HOMEOSTASIS IL-15 NOD mouse 
Tcf1 at the crossroads of CD4^＋ and CD8^＋ T cell identity
《Frontiers in Biology》2017年第2期83-93,共11页Jodi A. Gullicksrud Qiang Shan Hai-Hui Xue 
Transcription factors and DNA/histone modification enzymes work in concert to establish and maintain cell identity. CD4^＋ and CD8^＋ T cells are key players in cellular immunity with distinct functions. Recent studie...
关键词：Tcf1 Lef1 HDAC CD4^＋ T cells CD8^＋ T cells cell identity 
加味玉屏风汤对提高慢性病患者CD_4^+指标临床观察被引量：1
《上海中医药杂志》2007年第10期49-51,共3页孔昭东 张慧 曹波 冯春妹 余琛 
目的观察加味玉屏风汤提高慢性病患者CD4+指标的作用。方法对慢性病患者测得CD4+细胞(细胞芯片法)在200～500个/μl者,以自拟加味玉屏风汤干预治疗1～2个疗程(10～14d为1个疗程),观察治疗前后CD4+的变化。结果65例中显效29例,占45%;有...
关键词：慢性病 亚健康 中医药疗法 加味玉屏风汤 CD4^+T细胞 
Driving Forces of AIDS Pathogenesis:Massive CD4^+ T Lymphocyte Depletion and Abnormal Immune Activation
《Virologica Sinica》2009年第6期501-508,共8页Chang LI Qin-xue HU 
NSFC (30872357);CAS (KSCX2-YWR-144);MOST (2008zx10001-002, 2006CB504200)
The occurrence of massive CD4+ T cell depletion is one of the most prominent characteristics of human immunodeficiency virus type 1 (HIV-1) infection during acute phase, resulting in unrestorable destruction to the im...
关键词：HIV/AIDS CD4^＋ T cell depletion Gut-associated lymphoid tissue Immune activation PATHOGENESIS 
CD4^+ T cell-mediated presentation of non-infectious HIV-1 virion antigens to HIV-specific CD8^+ T cells被引量：3
《Chinese Medical Journal》2006年第19期1629-1638,共10页XU Jian-qing Franco Lori Julianna Lisziewicz 
This study was supported by a grant from the Major Basic Project of China (973) (No. 2005CB522903).
Background The mechanism of chronic immune activation and impairment of HIV-specific immune responses during chronic infection is not fully understood. However, it is known that high immune activation leads to more ra...
关键词：HIV antigen presenting CD4^＋ T cell CD8＋ T cell immune pathogenesis 
Interleukin-16 in asthma
《Chinese Medical Journal》2006年第12期1017-1025,共9页DENG Jing-min SHI Huan-zhong 
This study was supported in part by the National Natural Science Foundation of China (No. 30460051), and in part by the Program NCET-04-0835 for New Century Excellent Talents in Chinese Universities.
Bronchial asthma is a chronic inflammatory disease of the airways that is characterized by lymphocyte, eosinophil, and mast cell infiltration of the submucosa along with mucous gland hyperplasia and subepithelial fibr...
关键词：ASTHMA CD4^＋ T cells INTERLEUKIN-16 PATHOGENESIS 
Effect of perioperative autologous versus allogeneic blood transfusion on the immune system in gastric cancer patients被引量：20
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2007年第8期560-565,共6页CHEN Gang ZHANG Feng-jiang GONG Ming YAN Min 
Project supported by the Health Department of Zhejiang Province(No. 2004A040);the Education Department of Zhejiang Province (No. G20030486), China
Background： Allogeneic blood transfusion-induced immunomodulation （TRIM） and its adverse effect on the prognosis of patients treated surgically for cancer remain complex and controversial. However, the potential ri...
关键词：Transfusion-induced immunomodulation （TRIM） Autologous blood transfusion Allogeneic blood transfusion NEOPTERIN Interferon-gamma （IFN-γ） CD3^＋ CD4^＋ CD4^＋/CD8^＋ ratio 
Screening of aplastic anaemia-related genes in bone marrow CD4^+ T cells by suppressive subtractive hybridization
《Chinese Medical Journal》2007年第15期1326-1330,共5页ZHENG Miao LIU Wen-li FU Jin-rong SUN Han-ying ZHOU Jian-feng XU Hui-zhen 
a grant from the National Natural Science Foundation of China(No.30570773)
Background CD4^＋ T cells play a crucial role in the pathogenesis of aplastic anaemia. However, the mechanisms of over-proliferation, activation, infiltration of bone marrow and damage to haematopoietic ceils of CD4^...
关键词：aplastic anaemia  suppressive subtractive hybridization CD4^＋ T cell 
Characterization of CD4^+ T Cell Responses in Mice Infected with Schistosoma japonicum被引量：8
《Acta Biochimica et Biophysica Sinica》2006年第5期327-334,共8页Min-Jun JI Chuan SU Yong WANG Hai-Wei WU Xiao-Ping CAI Guang-Fu LI Xiang ZHU Xin-Jun WANG Zhao-Song ZHANG Guan-Ling WU 
This work was supported by the grants from the National Natural Science Foundation of China(No.30430600 and No.30100156)
To better understand the interaction between Schistosoma japonicum and its murine host, we characterized the immune response of CD4^＋ T cells generated during an experimental S. japonicum infection based on different...
关键词：Schistosoma japonicum CD4^＋ T cell immune deviation immune regulatory network 
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