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In vitro identification of nonalcoholic fatty liver diseaserelated protein hnRNPM被引量：1
《World Journal of Gastroenterology》2015年第6期1784-1793,共10页Jun-ichi Takino Kentaro Nagamine Masayoshi Takeuchi Takamitsu Hori 
Supported by Grants from the Japan Society for the Promotion of Science,No.22300264 and No.25282029
AIM:To study the formation of intracellular glyceraldehyde-derived advanced glycation end products(Glycer-AGEs)in the presence of high concentrations of fructose.METHODS:Cells of the human hepatocyte cell line Hep3B w...
关键词：ADVANCED glycation END-PRODUCTS FRUCTOSE Glycation 
Fluorescent advanced glycation end-products (ages) detected by spectro-photofluorimetry, as a screening tool to detect diabetic microvascular complications被引量：1
《Journal of Diabetes Mellitus》2012年第2期221-226,共6页Maria Pia de la Maza Fernando Garrido Nadia Escalante Laura Leiva Gladys Barrera Sylvia Schnitzler Mario Zanolli Juan Verdaguer Sandra Hirsch Natallia Jara Daniel Bunout 
BACKGROUND: Advanced glycation end-products (AGEs) are one of the mechanisms related to diabetic vascular complications. However, since AGEs are multiple and heterogeneous moieties, there is no universally accepted me...
关键词：Advanced Glycation END-PRODUCTS AGES MICROANGIOPATHY MICROVASCULAR COMPLICATIONS 
Involvement of the TAGE-RAGE system in non-alcoholic steatohepatitis: Novel treatment strategies被引量：5
《World Journal of Hepatology》2014年第12期880-893,共14页Masayoshi Takeuchi Jun-ichi Takino Akiko Sakasai-Sakai Takanobu Takata Tadashi Ueda Mikihiro Tsutsumi Hideyuki Hyogo Sho-ichi Yamagishi 
Supported by The Japan Society for the Promotion of Science(JSPS)KAKENHI Grant,No.19300254,22300264 and 25282029(Takeuchi M);Kanazawa Medical University,No.SR2012-04(Tsutsumi M);the Ministry of Education,Culture,Sports,Science,and Technology(MEXT),Regional Innovation Strategy Support Program(Takeuchi M)
Non-alcoholic fatty liver disease(NAFLD)is a major cause of liver disease around the world.It includes a spectrum of conditions from simple steatosis to non-alcoholic steatohepatitis(NASH)and can lead to fibrosis,cirr...
关键词：Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Advanced glycation end-products Toxic advanced glycation end-products Receptor for advanced glycation end-products Toxic advanced glycation end-products-receptor for advanced glycation end-products system Diabetes mellitus Cardiovascular disease Dietary fructose Dietary advanced glycation end-products 
Comprehensive analysis of advanced glycation end-products in commonly consumed foods:presenting a database for dietary AGEs and associated exposure assessment
《Food Science and Human Wellness》2024年第4期1917-1928,共12页Qiaozhi Zhang Huatao Li Ruixing Zheng Lili Cao Shufen Zhang Shuifeng Zhang Huadong Sheng Yuhao Jiang Yanbo Wang Linglin Fu 
the financial support received from the Natural Science Foundation of China(32202202 and 31871735)。
Advanced glycation end-products(AGEs)are a group of heterogeneous compounds formed in heatprocessed foods and are proven to be detrimental to human health.Currently,there is no comprehensive database for AGEs in foods...
关键词：Advanced glycation end-products Maillard reaction Processed foods Dietary database Exposure assessment 
Advanced glycation end-products change placental barrier function and tight junction in rats with gestational diabetes mellitus via the receptor for advanced glycation end products/nuclear factor-κB pathway
《BIOCELL》2023年第1期165-173,共9页YUEHUA SHI QIUYING YAN QIN LI WEI QIAN DONGYAN QIAO DONGDONG SUN HONG YU 
This work was financially supported by The Jiangsu Provincial Maternal and Child Health Key Talents Project(F202042).
The placenta plays an important role in nutrient transport to maintain the growth and development of the embryo.Gestational diabetes mellitus(GDM),the most common complication during pregnancy,highly affects placental...
关键词：Gestational diabetes mellitus Advanced glycation end-products RAGE-NF-κB Placental barrier Tight junction 
Inhibitory mechanism of flavonoids on dietary advanced glycation end products formation in food models
《Food and Health》2025年第2期35-38,共4页Meng-Yao Jin He Li 
financially supported by the National Natural Science Foundation of China(Grant No.32472468 and No.32001817);the Fundamental Research Program of Shanxi Province(202303021221123).
Advanced glycation end products(AGEs)are complex compounds formed through interaction of carbonyl groups from saccharides with amino groups in amino acids,proteins,lipids and nucleic acids,mainly via Maillard reaction...
关键词：flavonoid compounds advanced glycation end-products inhibitory mechanism reactive carbonyl species 
Contributions of the receptor for advanced glycation end products axis activation in gastric cancer被引量：2
《World Journal of Gastroenterology》2023年第6期997-1010,共14页Armando Rojas Cristian Lindner Iván Schneider Ileana González Miguel Angel Morales 
Compelling shreds of evidence derived from both clinical and experimental research have demonstrated the crucial contribution of receptor for advanced glycation end products(RAGE)axis activation in the development of ...
关键词：Gastric cancer Advanced glycation end-products Receptor of advanced glycation end-products ALARMINS Helicobacter pylori Chronic inflammation 
N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-κB pathway in rats被引量：1
《International Journal of Ophthalmology(English edition)》2024年第2期228-238,共11页Yu-Ze Zhao Xue-Ning Zhang Yi Yin Pei-Lun Xiao Meng Gao Lu-Ming Zhang Shuan-Hu Zhou Shu-Na Yu Xiao-Li Wang Yan-Song Zhao 
Supported by the National Natural Science Foundation of China(No.82071888);the Natural Science Foundation of Shandong Province(No.ZR2021MH351,No.ZR2020MH074);the Introduction and Cultivation Project for Young Innovative Talents in Shandong Province;Weifang Science and Technology Development Plan(No.2021GX057).
AIM:To observe the effects of N-acetylserotonin(NAS)administration on retinal ischemia-reperfusion(RIR)injury in rats and explore the underlying mechanisms involving the high mobility group box 1(HMGB1)/receptor for a...
关键词：retinal diseases retinal ischemia—reperfusion injury N-ACETYLSEROTONIN high mobility group box 1 receptor for advanced glycation end-products nuclear factor-κB RATS 
Receptor of advanced glycation end-products axis and gallbladder cancer:A forgotten connection that we should reconsider
《World Journal of Gastroenterology》2022年第39期5679-5690,共12页Armando Rojas Cristian Lindner Iván Schneider Ileana Gonzàlez Miguel Angel Morales 
Compelling evidence derived from clinical and experimental research has demonstrated the crucial contribution of chronic inflammation in the development of neoplasms,including gallbladder cancer.In this regard,data de...
关键词：Gallbladder cancer Advanced glycation end-products Receptor of advanced glycation end-products Chronic inflammation NUTRITION 
MK615 decreases RAGE expression and inhibits TAGE-induced proliferation in hepatocellular carcinoma cells被引量：6
《World Journal of Gastroenterology》2010年第42期5334-5341,共8页Yuhki Sakuraoka Tokihiko Sawada Toshie Okada Takayuki Shiraki Yoshikazu Miura Katsuya Hiraishi Tatsushi Ohsawa Masakazu Adachi Jun-ichi Takino Masayoshi Takeuchi Keiichi Kubota 
Supported by A Research Grant from the Biomarker Society
AIM:To investigate the proliferative effect of advanced glycation end-products(AGEs) and the role of their cellular receptor(RAGE) on hepatocellular carcinoma(HCC) cells,and the inhibitory effects of MK615,an extract ...
关键词：Hepatocellular carcinoma Receptor of advanced glycation end-product Advanced glycation endproducts MK615 Toxic advanced glycation end-products 
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