ALARMINS

作品数：9被引量：58H指数：3
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相关领域：医药卫生更多>>
相关作者：马晓春栾正刚更多>>
相关机构：中国医科大学附属第一医院更多>>
相关期刊：《Cellular & Molecular Immunology》《World Journal of Gastroenterology》《International Journal of Ophthalmology(English edition)》《World Journal of Diabetes》更多>>
相关基金：辽宁省教育厅基金国家自然科学基金广东省自然科学基金更多>>
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Hepatic Alarmins and Mitochondrial Dysfunction under Residual Hyperlipidemic Stress Lead to Irreversible NAFLD
《Journal of Clinical and Translational Hepatology》2023年第2期284-294,共11页Luminita Ivan Elena Uyy Viorel I.Suica Raluca M.Boteanu Aurel Cerveanu-Hogas Rune Hansen Felicia Antohe 
supported by the Romanian Academy and in part by a grant from the Romanian National Authority for Scientific Research and Innovation,CCCDI-UEFISCDI project COFUND-ERA-CVD-XploreCAD,No.41/2018 within PNCDI III.
Background and Aims:Nonalcoholic fatty liver disease(NAFLD)includes a range of progressive disorders generated by excess lipid accumulation in the liver leading to hepatic steatosis and eventually fibrosis.We aimed to...
关键词：Nonalcoholic fatty liver disease ATHEROSCLEROSIS PROTEOMIC ALARMINS FIBROSIS 
Contributions of the receptor for advanced glycation end products axis activation in gastric cancer被引量：2
《World Journal of Gastroenterology》2023年第6期997-1010,共14页Armando Rojas Cristian Lindner Iván Schneider Ileana González Miguel Angel Morales 
Compelling shreds of evidence derived from both clinical and experimental research have demonstrated the crucial contribution of receptor for advanced glycation end products(RAGE)axis activation in the development of ...
关键词：Gastric cancer Advanced glycation end-products Receptor of advanced glycation end-products ALARMINS Helicobacter pylori Chronic inflammation 
Hip prosthetic loosening and periprosthetic osteolysis:A commentary被引量：1
《World Journal of Orthopedics》2022年第6期574-577,共4页Bengt Mjöberg 
Prosthetic loosening and periprosthetic osteolysis have been debated for decades,both in terms of the timing and nature of the triggering events.The hypothesis of wear-particle-induced loosening states that wear parti...
关键词：Hip prosthesis Radiostereometric analysis Prosthesis failure OSTEOCLASTS Bone resorption ALARMINS 
Receptor for advanced glycation end-products axis and coronavirus disease 2019 in inflammatory bowel diseases:A dangerous liaison?被引量：4
《World Journal of Gastroenterology》2021年第19期2270-2280,共11页Armando Rojas Ivan Schneider Cristian Lindner Ileana Gonzalez Miguel Angel Morales 
Compelling evidence supports the crucial role of the receptor for advanced glycation end-products(RAGE)axis activation in many clinical entities.Since the beginning of the coronavirus disease 2019 pandemic,there is an...
关键词：COVID-19 Inflammatory bowel diseases Advanced glycation Angiotensinconverting enzyme 2 ALARMINS Receptor for advanced glycation end-products Receptor for advanced glycation end-products axis Inflammation 
Advanced-glycation end-products axis:A contributor to the risk of severe illness from COVID-19 in diabetes patients
《World Journal of Diabetes》2021年第5期590-602,共13页Armando Rojas Cristian Lindner Ileana Gonzàlez Miguel Angel Morales 
Compelling pieces of evidence derived from both clinical and experimental research has demonstrated the crucial role of the receptor for advanced-glycation end-products(RAGE)in orchestrating a plethora of proinflammat...
关键词：COVID-19 Diabetes mellitus Advanced glycation ALARMINS Advancedglycation end-products axis Inflammation 
Inflammatory niche:Mesenchymal stromal cell priming by soluble mediators被引量：3
《World Journal of Stem Cells》2020年第9期922-937,共16页Aleksandra Jauković Tamara Kukolj Hristina Obradović Ivana Okić-Đorđević Slavko Mojsilović Diana Bugarski 
Supported by the Ministry of Education,Science and Technological Development,Republic of Serbia,No.451-03-68/2020-14/200015.
Mesenchymal stromal/stem cells(MSCs)are adult stem cells of stromal origin that possess self-renewal capacity and the ability to differentiate into multiple mesodermal cell lineages.They play a critical role in tissue...
关键词：Mesenchymal stem cells Pro-inflammatory cytokines ALARMINS PRIMING Boosting the therapeutic potential 
Alarmins from conjunctival fibroblasts up-regulate matrix metalloproteinases in corneal fibroblasts被引量：1
《International Journal of Ophthalmology(English edition)》2020年第7期1031-1038,共8页Lin Chen Ye Liu Xiao-Shuo Zheng Hui Zheng Ping-Ping Liu Xiu-Xia Yang Yang Liu 
Supported by the National Natural Science Foundation of China(No.81770889);the Natural Science Foundation of Guangdong Province(No.2018A030313428)。
AIM:To explore the effects of alarmins produced by necrotic human conjunctival fibroblasts on the release of matrix metalloproteinases(MMPs)by human corneal fibroblasts(HCFs).METHODS:A necrotic cell supernatant(NHCS)w...
关键词：ALARMIN ocular burn matrix metalloproteinase corneal fibroblast conjunctival fibroblast inflammation 
HMGB1, IL-1α, IL-33 and S100 proteins： dual-function alarmins被引量：41
《Cellular & Molecular Immunology》2017年第1期43-64,共22页Damien Bertheloot Eicke Latz 
Our immune system is based on the close collaboration of the innate and adaptive immune systems for the rapid detection of any threats to the host. Recognition of pathogen-derived molecules is entrusted to specific ge...
关键词：ALARMIN HMGB1 IL-1Α IL-33 inflammation S100 proteins 
损伤相关分子模式与炎症反应被引量：6
《中国危重病急救医学》2009年第9期566-569,共4页栾正刚(综述) 马晓春(审校) 
辽宁省教育厅基金项目（2008836）
为辨别自身细胞的存活或识别微生物的入侵，多细胞动物已经进化出免疫监视、防御、修复机制。然而，目前仍不完全清楚这些机制是如何启动和协调配合的。因此，我们对相关基础研究和医疗研究现状做一个综述。
关键词：损伤相关分子模式 病原相关分子模式 ALARMINS 炎症 免疫 
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