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基于G-计算的高血压、抑郁在2型糖尿病与认知功能之间的因果多中介分析被引量：1
《山东大学学报（医学版）》2023年第10期101-108,共8页韩梅 孟维静 陶子琨 杨希 徐雅琪 穆华夏 卜伟晓 王素珍 石福艳 
国家自然科学基金(81872719);潍坊医学院公派国内访学项目经费资助。
目的探究2型糖尿病(T2DM)与认知功能之间的直接因果效应,以及高血压和抑郁在其因果关系中的中介效应。方法选取美国国家健康和营养检查调查(NHANES)数据库2013年至2014年60~80岁研究对象1306例,根据是否患T2DM分为对照组和T2DM组。采用G...
关键词：G-计算 因果多中介分析 2型糖尿病 认知功能 高血压 抑郁症 
Correlation between Combined Urinary Metal Exposure and Grip Strength under Three Statistical Models:A Cross-sectional Study in Rural Guangxi被引量：1
《Biomedical and Environmental Sciences》2024年第1期3-18,共16页LIANG Yu Jian RONG Jia Hui WANG Xue Xiu CAI Jian Sheng QIN Li Dong LIU Qiu Mei TANG Xu MO Xiao Ting WEI Yan Fei LIN Yin Xia HUANG Shen Xiang LUO Ting Yu GOU Ruo Yu CAO Jie Jing HUANG Chu Wu LU Yu Fu QIN Jian ZHANG Zhi Yong 
supported by the National Natural Science Foundation of China[rant Nos.81960583,81760577,81560523 and 82260629];Major Science and Technology Projects in Guangxi[GKAA22399 and AA22096026];the Guangxi Science and Technology Development Project[Grant Nos.AD 17129003 and 18050005];the Guangxi Natural Science Foundation for Innovation Research Team[2019GXNSFGA245002];the Innovation Platform and Talent Plan in Guilin[20220120-2];the Guangxi Scholarship Fund of Guangxi Education Department of China。
Objective This study aimed to investigate the potential relationship between urinary metals copper(Cu),arsenic(As),strontium(Sr),barium(Ba),iron(Fe),lead(Pb)and manganese(Mn)and grip strength.Methods We used linear re...
关键词：Urinary metals Handgrip strength Quantile g-computation Bayesian kernel machine regression 
Robust variance estimation for covariate-adjusted unconditional treatment effect in randomized clinical trials with binary outcomes
《Statistical Theory and Related Fields》2023年第2期159-163,共5页Ting Ye Marlena Bannick Yanyao Yi Jun Shao 
This work was supported by National Institute of Allergy and Infectious Diseases[NIAID 5 UM1 AI068617].
To improve the precision of estimation and power of testing hypothesis for an unconditional treatment effect in randomized clinical trials with binary outcomes,researchers and regulatory agencies recommend using g com...
关键词：G-computation modelassisted nonlinear covariate adjustment risk difference logistic regression STANDARDIZATION 
Associations of multiple metals exposure with immunoglobulin levels in pregnant women:Hangzhou Birth Cohort Study
《Journal of Environmental Sciences》2025年第5期560-572,共13页Jiena Zhou Lanfei Jin Yexinyi Zhou Kunhong Zhong Kegui Huang Qi Zhang Jun Tang Xue Zhang Lihe Peng Shuai Li Na Lv Dongdong Yu Qinheng Zhu Jing Guo Qiong Luo Guangdi Chen 
supported by the National Natural Science Foundation of China(No.U22A20358);Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents(No.2020-18).
Metal may affect maternal immune function,but few epidemiological studies have reported the associations between multiple-metal exposure and maternal immunoglobulin(Ig)levels.Based on the Hangzhou Birth Cohort Study,1...
关键词：METALS IMMUNOGLOBULIN Pregnant woman Quantile-based g-computation (QGC) Bayesian kernel machine regression (BKMR) 
基于g-computation联合混合效应模型控制未测混杂因素的因果推断方法模拟研究及实例验证
《中国卫生统计》2024年第5期691-696,共6页孙博然 芦文丽 陈永杰 
国家自然科学基金青年项目(81903416)。
目的通过模拟实验和实例验证探讨基于g-computation的联合混合效应模型(joint mixed-effects model,JMM)控制纵向研究未测混杂因素进行因果推断时的效果及性能特点。方法通过计算机模拟产生包含基线及两次随访时点的纵向数据,模拟条件...
关键词：纵向研究 未测混杂因素 g-computation 联合混合效应模型 
Association between exposure to a mixture of organochlorine pesticides and hyperuricemia in U.S.adults:A comparison of four statistical models
《Eco-Environment & Health》2024年第2期192-201,共10页Yu Wen Yibaina Wang Renjie Chen Yi Guo Jialu Pu Jianwen Li Huixun Jia Zhenyu Wu 
funded by the National Nature Science Foundation of China(82173613,82373681);the Scientific Project of Shanghai Municipal Health Commission(202140018).
The association between the exposure of organochlorine pesticides(OCPs)and serum uric acid(UA)levels remained uncertain.In this study,to investigate the combined effects of OCP mixtures on hyperuricemia,we analyzed se...
关键词：HYPERURICEMIA Organochlorine pesticide NHANES Weighted quantile sum Quantile g-computation Bayesian kernel machine regression 
Associations between Metals, Serum Folate, and Cognitive Function in the Elderly: Mixture and Mediation Analyses
《Environment & Health》2024年第12期865-874,共10页Luli Wu Ye Xin Junrou Zhang Xin Yang Tian Chen Piye Niu 
supported by the National Natural Science Foundation of China(No.81973007).
Exposure to metals may potentially impact cognitive health in the elderly;however,the evidence remains ambiguous.The specific role of serum folate in this relationship is also unclear.We aimed to evaluate the individu...
关键词：METALS Cognitive function Serum folate Quantile g-computation Bayesian kernel machine regression Mediating effect 
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