化学性食物中毒因子检测技术研究进展  

Research advances on toxicological screening techniques for chemical food poisoning accidents

作　　者：邵兵[1,2] 张晶[1,2] 高馥蝶 郭娟[1,2] 

机构地区：[1]北京市疾病预防控制中心食物中毒诊断溯源技术北京市重点实验室,北京100013 [2]北京市预防医学研究中心,北京100013

出　　处：《食品安全质量检测学报》2013年第3期625-635,共11页Journal of Food Safety and Quality

基　　金：国家科技支撑计划课题(2011BAK10B06);北京市卫生系统高层次卫生技术人才培养计划项目~~

摘　　要：化学性食物中毒因子的确证因其毒物的不确定性和基质的复杂性一直是卫生检验领域的一个难题。本文从目标毒物分析(亚硝酸盐、农药、杀鼠剂、麻醉品及精神药品、生物毒素以及其它药物等)和非目标毒物筛查(样本前处理技术和仪器筛查技术)两个方面综述了当前化学性毒物检测技术的的主要研究进展,介绍了相关方法的原理、应用、不足及发展方向,以期为化学性食物中毒事件处置及未来研究提供借鉴。Toxicological screening for chemical food poisoning accident is always a big challenge in the field of analytical chemistry,due to not only the unknown non-target poisoning substance but also the complex sample matrix.This article summarized the main research advance on target toxin detection(nitrites,pesticides,rodenticides,narcotics and psychotropic drugs,biological toxins and other drugs) and non-target toxin screening techniques(sample pretreatment technologies and instrument analytical methodologies) for chemical food poisoning accident.Principles,applications,limitations as well as possible tendency have been discussed.It will provide useful information for the response of poisoning incident and relevant study in future.

关 键 词：食物中毒 毒物 筛查技术 

分 类 号：R155.5[医药卫生—营养与食品卫生学]