Antinociceptive activity of Ricinus communis L.leaves  

作　　者：Dnyaneshwar J Taur Maruti G Waghmare Rajendra S Bandal Ravindra Y Patil 

机构地区：[1]Department of Pharmacognosy,SVPM's College of Pharmacy [2]Department of Pharmaceutical Chemistry,SVPM's College of Pharmacy [3]Department of Pharmacognosy,PDEA's Shankarrao Ursal College of Pharmaceutical Sciences and Research Center

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2011年第2期139-141,共3页亚太热带生物医学杂志（英文版）

摘　　要：Objective:To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves(MRCL).Methods:Antinociceptive activity was evaluated using acetic acid induced writhing test,formalin induced paw licking and tail immersion method in mice at doses of 100,125 and 130 mg/kg bw.Results:The results indicated that MRCL exhibited considerable antinociceptive activity against three classical models of pain in mice.Preliminary phytochemical analysis suggested the presence of saponin,steroids and alkaloids.Conclusions:It can be concluded that MRCL possesses antinociceptive potential that may be due to saponin,steroids and alkaloids in it.Objective:To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves(MRCL).Methods:Antinociceptive activity was evaluated using acetic acid induced writhing test,formalin induced paw licking and tail immersion method in mice at doses of 100,125 and 130 mg/kg bw.Results:The results indicated that MRCL exhibited considerable antinociceptive activity against three classical models of pain in mice.Preliminary phytochemical analysis suggested the presence of saponin,steroids and alkaloids.Conclusions:It can be concluded that MRCL possesses antinociceptive potential that may be due to saponin,steroids and alkaloids in it.

关 键 词：RICINUS communis ANALGESIC ANTINOCICEPTIVE WRITHING FORMALIN 

分 类 号：R285.5[医药卫生—中药学]