Globally,around 6,457 weather-related disasters,such as earthquakes,floods,cyclones,and landslides,claimed 606,000 lives and affected more than four billion people between 1995 and 2015,according to an international d...
Pain is a sensation which in many cases represents the only symptom for the diagnosis of several disorders. Throughout ages man has used many different remedies for pain relief, among which medicinal herbs are most co...
Objective:To evaluate the analgesic,neuropharmacological,cytotoxic and thrombolytic potentials of the aqueous,ethanol and ethyl acetate extracts of Kalanchoe pinnata leaves.Methods:At the dose of 400 mg/kg body weight...
Aim: To characterize the pharmacological profiles of a novel K-opioid receptor agonist MB-1C-OH. Methods: [3H]diprenorphine binding and [35S]GTPyS binding assays were performed to determine the agonistic properties ...
Aim: 2-(3',5'-Dimethoxybenzylidene) cyclopentanone (DMBC) is a novel synthetic compound with antinociceptive activities. The aim of this study was to investigate the roles of the autophagic-lysosomal pathway in...
supported by the management and faculty of Jaipur National University,Jaipur,Rajasthan,India
Objective:To evaluate the ann-nociceptive activity of Tecomaria capensls(T.capensis) leaves extract(TCLE) using different models in rats by acetic acid induced writhing test,(b) tail-flick test(c) tail-clip test.Metho...
Objective:To evaluate the anti-inflammatory and analgesic activities of the ethanol and aqueous extracts of prop roots of Pandanus fascicularis(P.fascicularis) Lam(pandanaceae).And provide experimental evidence for it...
Objective:To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves(MRCL).Methods:Antinociceptive activity was evaluated using acetic acid induced writhing test,formalin induced paw l...
Objective:To evaluate the analgesic activity of the ethyl acetate,methanol and aqueous extracts of Plewotus eous(P.eous) mushroom.Methods:The dried fruiting bodies were extracted with ethyl acetate,methanol and water....
In vivo DNA often appears in supercoiled states. This phenomenon is related to the constraints imposed on DNA structures, such as co-valenced ring closure, protein binding. When a certain amount of supercoiling isconf...