相关期刊:《Chinese Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Journal of Pharmacy and Pharmacology》更多>>
Background: Codiaeum variegatum, sometimes called garden croton, is a tropical plant in the Euphorbiaceae family. Historically used to cure various conditions, including intestinal infections, fever, ulcers, wounds, a...
Background: Diospyros malabarica (Desr.) Kostel, a small to medium-sized tree in the Ebenaceae family, is known as “Deshi Gab” in Bangladesh. Fever, diabetes, snake bite, diarrhea, biliousness, and ulcer ailments ar...
Background:Ceiba pentandra is a medicinal plant used as alternative therapy to control parasitic nematodes in livestock.Objective:This study aims to investigate anti-parasitic effect of aqueous stem back extract of Ce...
This work was supported by the National Natural Science Foundation of China(51873175);the Special Fund of Guiding Scientific and Technological Innovation and Development in Gansu Province,China(2019ZX-05).
Quantitative evaluation of analgesic efficacy improves understanding of the antinociceptive mechanisms of new analgesics and provides important guidance for their development.Lappaconitine(LA),a potent analgesic drug ...
Oral therapy of tramadol,an opiate analgesic,undergoes extensive hepatic metabolism and requires frequent administration.Transdermal therapy by virtue can overcome these issues and can improve the efficacy and reduce ...
supported by grants from the National Natural Science Foundation of China(Nos.21572274 and 21732008);the CAMS Innovation Fund for Medical Sciences(No.2016-I2M1-010,China)
Twelve new grayanoids(1-12)along with five known compounds were isolated from flowers of Rhododendron molle.Their structures were fully characterized using a combination of spectroscopic analyses,computational calcula...
the National Natural Science Foundation of China(81870870 to C.-Y.J.,81202513,and 81471142);Natural Science Foundation for Young Scientists of Jiangsu Province(BK20161033);the Key Project of Nanjing Medical University Sciente and Technology Innovation Foundation(2017NJMUCX004).
The development of opioid-induced analgesic tolerance is a clinical challenge in long-term use for managing chronic pain. The mechanisms of morphine tolerance are poorly understood. Mitochondria-derived reactive oxyge...
National Natural Science Foundation of China(81673282;81273355).
OBJECTIVE Considerable effort has recently been directed at developing multifunctional opioid drugs as an alternative strategy to minimize the unwanted side effects of opioid analgesics.We recently developed a novel m...
supported by FUNDECT(Foundation for Support for the Development of Education,Science and Technology of the State of Mato Grosso do Sul);(FUNDECT/CAPES N°26/2014)Coordination for the Improvement of Higher Level Education Personnel(CAPES);National Council for Scientific and Technological Development(CNPq)
To evaluate the antinociceptive and anti-inflammatory activities and the toxic effects of Rlhipicephalus microplus saliva for elucidating the modulation mechanism between arthropod saliva and host.Methods:For saliva c...
financially supported by the Higher Education Commission of Pakistan(No.2003)
Two new sesquiterpenes, trivially named ricinusoids A(1) and ricinusoids B(2), were isolated from ethyl acetate fraction of Ricinus communis. The structures of new compounds were elucidated by detailed spectroscopic t...