SESQUITERPENOIDS

作品数：75被引量：134H指数：6
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相关领域：理学医药卫生更多>>
相关作者：屠鹏飞付强肖美添陈筱清周思祥更多>>
相关机构：北京大学中国科学院华中农业大学中国药科大学更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》《Asian Journal of Traditional Medicines》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划上海市青年科技启明星计划更多>>
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Structurally diverse sesquiterpenoids with anti-MDR cancer activity from Penicillium roqueforti
《Chinese Journal of Natural Medicines》2025年第4期504-512,共9页Shuyuan Mo Nanjin Ding Zhihong Huang Jun Yao Weiguang Sun Jianping Wang Yonghui Zhang Zhengxi Hu 
supported by the National Natural Science Foundation of China(Nos.82273811,32470417,and U22A20380);the National Program for Support of Top-notch Young Professionals(No.0106514050);the Hubei Provincial Natural Science Foundationof China(No.2024AFA028);the National Key R&D Program of China(No.2021YFA0910500);the Science and Technology Major Project of Hubei Province(Nos.2021ACA012 and 2024BCB021);the Chinese Medicine Research Foundation of the Health Commission of Hubei Province(No.ZY2025Z013)。
Five novel nor-eremophilane-type sesquiterpenoids,peniroqueforins E–H and J(1–4 and 7),two new eremophilane-type sesquiterpenoids,peniroqueforins I and K(5 and 8),and a new eudesmane-type sesquiterpenoid,peniroquefo...
关键词：Penicillium roqueforti SESQUITERPENOIDS Nor-sesquiterpenoids Anti-MDR cancer activity 
Highly oxidized sesquiterpenoids from Parasenecio rubescens and assessment of their cytotoxicity
《Chinese Journal of Natural Medicines》2024年第11期1020-1029,共10页JIN An DUAN Fangfang RUAN Hanli 
supported by the National Natural Science Foundation of China(Nos.22077041,81803847 and 31770380).
A phytochemical investigation of the whole plant of Parasenecio rubescens(S.Moore)Y.L.Chen yielded 14 previ-ously undescribed,highly oxidized bisabolane-type sesquiterpenoids,named pararunines L-Y,along with one known...
关键词：Parasenecio rubescens Asteraceae Bisabolane-type sesquiterpenoids Oplopane-type sesquiterpenoid Cytotoxic activity 
Total Synthesis of Laurane and Guaiane Sesquiterpenoids via Oxidative Nazarov Reaction
《Chinese Journal of Chemistry》2024年第11期1267-1274,共8页Yuye Chen Wenqing Chen Zhiting Zhang Jing Xu 
support from the National Natural Science Foundation of China(Nos.21971104,22001114 and 22271136);Shenzhen Science,Technology and Innovation Commission(JCYJ20220814203252001);Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis(ZDSYS20190902093215877);Guangdong Provincial Key Laboratory of Catalysis(No.2020B121201002);Guangdong Innovative Program(No.2019BT02Y335);Education Department of Guangdong Province,Key Research Projects in Colleges and Universities in Guangdong Province(2021ZDZX2035);Shenzhen Nobel Prize Scientists Laboratory Project(C17783101),Innovative Team of Universities in Guangdong Province(2020KCXTD016);Guangdong Natural Science Foundation(2022A1515010456)is greatly appreciated.
As one of the most common structural motifs in natural products,cyclopentenones usually can be fabricated by Nazarov cyclization using divinyl ketones or functionalized tertiary divinyl carbinols(TDCs)as substrates.Ho...
关键词：Total synthesis Synthetic methods SESQUITERPENOIDS Oxidative Nazarov reaction ELECTROCYCLIZATION Oxoammonium salt Pericyclic reaction ANNULATION 
Artemdubinoids A-N:novel sesquiterpenoids with antihepatoma cytotoxicity from Artemisia dubia被引量：1
《Chinese Journal of Natural Medicines》2023年第12期902-915,共14页GAO Zhen LI Tianze MA Yunbao HUANG Xiaoyan GENG Changan ZHANG Xuemei CHEN Jijun 
This work was supported by the Key Program of the National Natural Science Foundation of China(No.22137008);the Xingdian Yingcai Project(No.YNWR-KJLJ-2019-002);the Youth Innovation Promotion Association,CAS(No.2020386);the Reserve Talents of Young and Middle-aged Academic and Technical Leaders in Yunnan Province(No.202105AC160021);the State Key Laboratory of Phytochemistry and Plant Resources in West China(P2021-ZZ06).
In pursuit of effective agents for hepatocellular carcinoma derived from the Artemisia species,this study built upon initial findings that an ethanol(EtOH)extract and ethyl acetate(EtOAc)fraction of the aerial parts o...
关键词：Artemdubinoids A-N Artemisia dubia SESQUITERPENOIDS Antihepatoma activity 
Natural Sesquiterpenoids, Diterpenoids, Sesterterpenoids, and Triterpenoids with Intriguing Structures from 2017 to 2022
《Chinese Journal of Chemistry》2023年第22期3115-3132,共18页Xiaotian Zhang Meijia Zheng Aimin Fu Qin Li Chunmei Chen Hucheng Zhu Yonghui Zhang 
This review covers the isolation,structural determination,plausible biosynthetic pathways,and biological activities of 166 natural terpenoids including 57 sesquiterpenoids,65 diterpenoids,15 sesterterpenoids,and 29 tr...
关键词：SESQUITERPENOIDS DITERPENOIDS Sesterterpenoids TRITERPENOIDS Structura scaffolds Biosynthetic pathways Structure elucidation Drug discovery 
Clavukoelloids A—M,Thirteen Rare N-Containing Nardosinane Type Sesquiterpenoids from the Soft Coral Clavularia koellikeri
《Chinese Journal of Chemistry》2023年第12期1491-1496,共6页Xiao Han Zhe Wang Anran Fu Kun Liu Zongchen Ma Xuli Tang Dahai Zhang Guoqiang Li 
supported by the National Natural Science Foundation of China(Nos.U2006204,41776136,and 2181101213)。
Thirteen new nitrogen-containing nardosinane-type sesquiterpenoids,clavukoelloids A-M(1-13)with unique acrylamide fragments vs.the reported general nardosinane-type sesquiterpenoids containing lactone,were isolated fr...
关键词：Soft coral Clavularia koellikeri Nardosinane-type sesquiterpenoids Absolute configurations ACTIVITIES Natural products NMR spectroscopy TERPENOIDS 
A review of research on the chemical constituents and pharmacological effects of Elephantopus tomentosus L.
《Asian Journal of Traditional Medicines》2023年第1期15-24,共10页Shuai Shen Ming Bai Shaojiang Song 
Elephantopus tomentosus,belonging to the genus Elephantopus,is widely distributed in the coastal areas of southern China and tropical regions,used locally as traditional folk medicine.Previous phytochemistry studies o...
关键词：Elephantopus tomentosus chemical composition pharmacological activities SESQUITERPENOIDS 
A comprehensive review on the chemical constituents,sesquiterpenoid biosynthesis and biological activities of Sarcandra glabra被引量：2
《Natural Products and Bioprospecting》2023年第1期30-92,共63页Jin-Ning Chu Premanand Krishnan Kuan-Hon Lim 
Sarcandra glabra(Thunb.)Nakai is a perennial evergreen herb categorised within the Sarcandra Gardner genus under the Chloranthaceae family.Indigenous to tropical and subtropical regions of East Asia and India,this spe...
关键词：Sarcandra glabra CaoShanHu Traditional Chinese medicine Lindenane-type sesquiterpenoids Biosynthetic pathway Biological activities 
Seven drimane-type sesquiterpenoids from an earwig-associated Aspergillus sp.
《Chinese Journal of Natural Medicines》2023年第1期58-64,共7页SALMAN Khan ZHU Hongjie SUN Ziqian LI Yilin WANG Lan WANG Rong GUO Zhikai JIAO Ruihua 
This work was supported by the Central Publicinterest Scientific Institution Basal Research Fund for CATAS-ITBB(Nos.1630052022016,1630052019011,and 19CXTD-32);the National Key Research and Development Program(No.2018YFA0902000);the National Natural Science Foundation of China(No.81991524);the Hainan Provincial Basic and Applied Basic Research Fund for High-Level Talents in Natural Science(Nos.2019RC306 and 2019RC352).
Drimane-type sesquiterpenoids are widely distributed in fungi.From the ethyl acetate extract of the earwig-derived Aspergillus sp.NF2396,seven new drimane-type sesquiterpenoids,named drimanenoids A−G(1−7),were isolate...
关键词：Fungus SESQUITERPENOIDS Drimane-type Antibacterial CYTOTOXIC Aspergillus sp. 
The chromosome-scale genome of Phoebe bournei reveals contrasting fates of terpene synthase (TPS)-a and TPS-b subfamilies被引量：7
《Plant Communications》2022年第6期26-42,共17页Xiao Han Junhong Zhang Shuang Han Sun Li Chong Guanliang Meng Minyan Song Yang Wang Shengcai Zhou Chengcheng Liu Luhuan Lou Xiongzhen Lou Longjun Cheng Erpei Lin Huahong Huang Qi Yang Zaikang Tong 
supported by the Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding(grant 2021C02070-10);the National Natural Science Foundation of China(grants 32171828 and 32101545);the State Key Laboratory of Subtropical Silviculture(grant ZY20180204).
Terpenoids,including aromatic volatile monoterpenoids and sesquiterpenoids,function in defense against pathogens and herbivores.Phoebe trees are remarkable for their scented wood and decay resistance.Unlike other Laur...
关键词：Phoebe bournei genome sequence terpene synthases SESQUITERPENOIDS positive selection pathogen resistance 
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