Colorectal hepatic metastasis: Evolving therapies  

作　　者：Francisco Igor B Macedo Tafadzwa Makarawo 

机构地区：[1]Department of Surgery, Providence Hospital and Medical Centers, Southfield,MI 48075, United States

出　　处：《World Journal of Hepatology》2014年第7期453-463,共11页世界肝病学杂志（英文版）（电子版）

摘　　要：The approach for colorectal hepatic metastasis has advanced tremendously over the past decade. Multidrug chemotherapy regimens have been successfully introduced with improved outcomes. Concurrently, adjunct multimodal therapies have improved survival rates, and increased the number of patients eligible for curative liver resection. Herein, we described major advancements of surgical and oncologic management of such lesions, thereby discussing modern chemotherapeutic regimens, adjunct therapies and surgical aspects of liver resection.The approach for colorectal hepatic metastasis has advanced tremendously over the past decade. Multidrug chemotherapy regimens have been successfully introduced with improved outcomes. Concurrently, adjunct multimodal therapies have improved survival rates, and increased the number of patients eligible for curative liver resection. Herein, we described major advancements of surgical and oncologic management of such lesions, thereby discussing modern chemotherapeutic regimens, adjunct therapies and surgical aspects of liver resection.

关 键 词：COLORECTAL cancer Hepatic metastasis HEPATECTOMY Survival Chemotherapy 5-FLUOROURACIL LEUCOVORIN and OXALIPLATIN 

分 类 号：R735.34[医药卫生—肿瘤]