LEUCOVORIN

作品数：20被引量：60H指数：5
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相关领域：医药卫生更多>>
相关作者：徐宏彬更多>>
相关机构：上海市第十人民医院四川大学更多>>
相关期刊：《癌症》《Cellular & Molecular Immunology》《World Journal of Gastroenterology》《Gastroenterology Report》更多>>
相关基金：国家自然科学基金更多>>
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Irinotecan hydrochloride liposome HR070803 in combination with 5-fluorouracil and leucovorin in locally advanced or metastatic pancreatic ductal adenocarcinoma following prior gemcitabine-based therapy (PAN-HEROIC-1): a phase 3 trial被引量：1
《Signal Transduction and Targeted Therapy》2024年第10期4628-4636,共9页Jiujie Cui Shukui Qin Yuhong Zhou Shuang Zhang Xiaofeng Sun Mingjun Zhang Jiuwei Cui Weijia Fang Kangsheng Gu Zhihua Li Jufeng Wang Xiaobing Chen Jun Yao Jun Zhou Gang Wang Yuxian Bai Juxiang Xiao Wensheng Qiu Bangmao Wang Tao Xia Chunyue Wang Li Kong Jiajun Yin Tao Zhang Xionghu Shen Deliang Fu Chuntao Gao Huan Wang Quanren Wang Liwei Wang 
Jiangsu Hengrui Pharmaceuticals Co.,Ltd.
Liposomal irinotecan has shown promising antitumor activity in patients with advanced or metastatic pancreatic ductal adenocarcinoma (PDAC) who have undergone prior gemcitabine-based therapies. This randomized, double...
关键词：METASTATIC adenocarcinoma sided 
Effect of intra-operative chemotherapy with 5-fluorouracil and leucovorin on the survival of patients with colorectal cancer after radical surgery: a retrospective cohort study被引量：2
《Chinese Medical Journal》2023年第7期830-839,共10页Xuhua Hu Zhaoxu Zheng Jing Han Baokun Li Ganlin Guo Peiyuan Guo Yang Yang Daojuan Li Yiwei Yan Wenbo Niu Chaoxi Zhou Zesong Meng Jun Feng Bin Yu Qian Liu Guiying Wang 
Youth Science and Technology Project of Hebei Health Commission(No.20210029);Hebei Provincial Natural Science Foundation Precision Medicine Joint Project(No.H2020206485);Hebei Provincial Department of Science and Technology Key Project(No.206Z7705G)
Background:The effect of intra-operative chemotherapy(IOC)on the long-term survival of patients with colorectal cancer(CRC)remains unclear.In this study,we evaluated the independent effect of intra-operative infusion ...
关键词：Colorectal cancer Intra-operative chemotherapy Overall survival Retrospective cohort study Stage 
A novel chemotherapy strategy for advanced hepatocellular carcinoma: a multicenter retrospective study被引量：4
《Chinese Medical Journal》2022年第19期2338-2343,共6页Juxian Sun Chang Liu Jie Shi Nanya Wang Dafeng Jiang Feifei Mao Jingwen Gu Liping Zhou Li Shen Wan Yee Lau Shuqun Cheng 
National Natural Science Foundation of China(No.82073293);Clinical Science and Technology Innovation Project of Shanghai Shenkang Hospital Development Center(Joint Project of Emerging Frontier Technology)(SHDC12018116);the Key Project of Natural Science Foundation of China(No:81730097)。
Background:Chemotherapy is a common treatment for advanced hepatocellular carcinoma,but the effect is not satisfactory.The study aimed to retrospectively evaluate the effects of adding all-trans-retinoic acid(ATRA)to ...
关键词：Hepatocellular carcinoma ATRA plus FOLFOX4 Overall survival All-trans-retinoic acid Fluorouracil LEUCOVORIN OXALIPLATIN 
Neutrophile-to-lymphocyte,lymphocyte-to-monocyte,and platelet-tolymphocyte ratios as prognostic and response biomarkers for resectable locally advanced gastric cancer被引量：3
《World Journal of Gastrointestinal Oncology》2022年第7期1307-1323,共17页Tiago Cruz Tomás Ines Eiriz Marina Vitorino Rodrigo Vicente Joao Gramaca Alicia Guadalupe Oliveira Paulo Luz Mafalda Baleiras Ana Sofia Spencer Luísa Leal Costa Patrícia Liu Joana Mendonca Magno Dinis Teresa Padrao Marisol Correia Goncalo Atalaia Michelle Silva Teresa Fiúza 
BACKGROUND Perioperative fluorouracil plus leucovorin,oxaliplatin,and docetaxel(FLOT)improves prognosis in locally advanced gastric cancer(LAGC).Neutrophil-to-lymphocyte(NLR),lymphocyte-tomonocyte(LMR),and platelet-to...
关键词：Gastric cancer Perioperative fluorouracil plus leucovorin oxaliplatin and docetaxel Neutrophil-to-lymphocyte Lymphocyte-to-monocyte Platelet-to-lymphocyte Tumor regression grade 
The“Chinese Expert Consensus on the Clinical Application of the Chinese Modified Triplet Combination with Irinotecan(CPT-11),Oxaliplatin(LOHP),Continuous Infusion 5-Fluorouracil,and Leucovorin for Colorectal Cancer”
《Gastroenterology Report》2021年第4期279-289,I0001,共12页Yanhong Deng Chinese Southwest Oncology Group-the Committee of Colorectal Cancer 
supported by The National Key Research and Development Plan of China[2019YFC1316003].
Colorectal cancer is the second most common malignant tumor in China.The FOLFOXIRI regimen,which combines 5-fluorouracil/leucovorin,oxaliplatin,and irinotecan,is a high-intensity and highly effective chemotherapy regi...
关键词：colorectal cancer FOLFOXIRI China expert consensus 
Effects of oxaliplatin, leucovorin and fluorouracil on serum tumor markers, VEGF, CRP and matrix metalloproteinases in patients with advanced esophageal cancer
《Journal of Hainan Medical University》2017年第16期94-97,共4页Lei Lei Xu Li Yu-Han Duan Hong Xu 
Objective: To investigate the effects of oxaliplatin, leucovorin and fluorouracil on serum tumor markers, VEGF, CRP and matrix metalloproteinases in patients with advanced esophageal cancer. Methods: From March 2012 t...
关键词：ESOPHAGEAL cancer OXALIPLATIN LEUCOVORIN Fluorouracil Serum BIOCHEMICAL INDICATOR 
PhaseⅡstudy of oxaliplatin combined with S-1 and leucovorin(SOL)for Chinese patients with metastatic colorectal cancer被引量：6
《Chinese Journal of Cancer》2016年第3期126-132,共7页zhi-qiang wang dong-sheng zhang nong xu de-yun luo yan-hong deng feng-hua wang hui-yan luo miao-zhen qiu yu-hong li rui-hua xu 
Background:Fluoropyrimidine and oxaliplatin are widely used for patients with colorectal cancer.This phase II study was conducted to evaluate the efficacy and safety of the combination of S-1,oxaliplatin,and leucovori...
关键词：COLORECTAL cancer  Oxaliplatin  S-1  LEUCOVORIN 
Evidence-based medical oncology and interventional radiology paradigms for liver-dominant colorectal cancer metastases被引量：4
《World Journal of Gastroenterology》2016年第11期3127-3149,共23页Alan Alper Sag Fatih Selcukbiricik Nil Molinas Mandel 
Colorectal cancer metastasizes predictably, with liver predominance in most cases. Because liver involvement has been shown to be a major determinant of survival in this population, liver-directed therapies are increa...
关键词：Colonic neoplasms Rectal neoplasms Neoplasm metastasis Antineoplastic agents FOLFOX protocol IRINOTECAN 5-flurouracil and leucovorin protocol Radiofrequency ablation Microwave ablation CHEMOEMBOLIZATION Therapeutic Immunotherapy 
A Multicenter Cohort Study for XELOX (Capecitabine, Leucovorin plus Oxaliplatin) Therapy as First-Line Treatment in Elderly Patients with Unresectable Colorectal Cancer
《Journal of Cancer Therapy》2015年第2期153-162,共10页Tetsu Yamamoto Ryoji Hyakudomi Shinichi Sugimoto Atsuo Tokuka Yoshitoshi Sato Satoshi Nagai Hikota Hayashi Masahikoo Igarashi Kenji Takubo Yoshitsugu Tajima 
Oxaliplatin-based chemotherapy with bevacizumab is now widely used for colorectal cancer patients. This study evaluated the efficacy and tolerability of XELOX (capecitabine + oxaliplatin + leucovorin combined) therapy...
关键词：Colorectal Cancer OXALIPLATIN CAPECITABINE BEVACIZUMAB Elderly Patients 
Colorectal hepatic metastasis: Evolving therapies被引量：9
《World Journal of Hepatology》2014年第7期453-463,共11页Francisco Igor B Macedo Tafadzwa Makarawo 
The approach for colorectal hepatic metastasis has advanced tremendously over the past decade. Multidrug chemotherapy regimens have been successfully introduced with improved outcomes. Concurrently, adjunct multimodal...
关键词：COLORECTAL cancer Hepatic metastasis HEPATECTOMY Survival Chemotherapy 5-FLUOROURACIL LEUCOVORIN and OXALIPLATIN 
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