Experimental study of the enhancement effect of aminopeptidase N inhibitor ubenimex on the differentiation induction activity of all-trans-retinoic acid in acute promyeiocytic leukemia cells and its mechanism  

作　　者：钱习军 

机构地区：[1]Dept Hematol 1st Affili Hosp,Med Coll,Zhejiang Univ,Hangzhou 310003

出　　处：《China Medical Abstracts(Internal Medicine)》2006年第4期224-225,共2页中国医学文摘（内科学分册（英文版）

摘　　要：Objective To investigate the effect of aminopeptidase N inhibitor ubenimex on differentiation induction of alltrans -retinoic acid (ATRA) in acute promyelocytic leukemia (APL) cells and its mechanism. Methods The expression of CD11b was analyzed by flow cytometry and nitroblue-tetrazolium (NBT) reduction assay was per-

关 键 词：induction CYTOMETRY ATRA TETRAZOLIUM phospho ALONE INHIBIT 

分 类 号：R733.71[医药卫生—肿瘤]