SELECTINS IN CORONARY ATHEROSCLEROTIC DISEASE:A REVIEW  

作　　者：李远方 胡健 

出　　处：《China Medical Abstracts(Internal Medicine)》2001年第1期42-46,共5页中国医学文摘（内科学分册（英文版）

摘　　要：The development of atherosclerotic lesions appears to be inflammatory in nature. It involves the recruitment of blood monocytes to the vascular endothelium, followed by intimal infiltration. Monocytes differentiate to macrophages, then internalize lipids to form foam cells, thus develop fatty streak lesion. A wide range of adhesion molecules governs these interactions between cells, among these molecules are selectins. Selectins mediate the first step in leukocyte adhesion at sites of inflammation or injury, characterized by rolling and

关 键 词：ENDOTHELIUM macrophages PLAQUES inflammation lipids infiltration ANGINA DIFFERENTIATE unstable LEUKOCYTE 

分 类 号：R543.3[医药卫生—心血管疾病]