supported by the Spanish Government(ISCIII-FEDER)PI20/01063;by Navarra Government(PC 060-061 and PC 192-193);Fundación Gangoiti(to MSA).LA was funded by FPU19/03255.
Neuroinflammation is associated with Parkinson’s disease:Reactive gliosis and neuroinflammation are hallmarks of Parkinson’s disease(PD),a multisystem neurodegenerative disorder characterized by a progressive loss o...
Supported by Hebei Province Medical Science Research Project Plan,No.20230755.
BACKGROUND Colony-stimulating factor 3(CSF3)and its receptor(CSF3R)are known to promote gastric cancer(GC)growth and metastasis.However,their effects on the immune microenvironment remain unclear.Our analysis indicate...
supported by the grant from the National Key Research and Development Program(No.2021YFC2400603).
Background:Leukocyte telomere length(LTL)shortening,a biomarker of telomere attrition,has been linked to multiple diseases.However,the relationship between LTL and digestive diseases remains uncertain.This study aimed...
Objective:Observational studies have reported conflicting results on the association between leukocyte telomere length(LTL)and polycystic ovary syndrome(PCOS).This study evaluated the causal effect of LTL on PCOS in E...
Leukocyte immunoglobulin‐like receptor B4(LILRB4)significantly impacts immune regulation and the pathogenesis and progression of various cancers.This review discusses LILRB4's structural attributes,expression pattern...
supported by the Grants of 62331025 and 62121003 from the National Natural Science Foundation of China.
Microfluidic impedance flow cytometry has been widely used in leukocyte differential and counting,but it faces a bottleneck due to the trade-off between impedance detection throughput and sensitivity.In this study,a m...
supported by grants from National Natural Science Foundation of China(Nos.82350105,82270228,and 82070184);Science,Technology&Innovation Project of Xiongan New area(No.2023XACX0004);Beijing Nova Program(No.20220484235);Clinical Medicine Plus X-Young Scholars Project of Peking University,the Fundamental Research Funds for the Central Universities,Peking University People’s Hospital Research and Development Funds(No.RDL2021-01)。
Leukocyte immunoglobulin-like receptor(LILR)B4(also known as ILT3/CD85k)is an immune checkpoint protein that is highly expressed in solid tumors and hematological malignancies and plays a significant role in the patho...
H.I.was supported by a Natural Sciences and Engineering Council(NSERC)postdoctoral fellowship and a Michael Smith Health Research BC Research Trainee Award;J.B.was supported by and NSERC Undergraduate Student Research Award;G.S.J.was supported by an Indigenous Scholar’s Award;J.P.L is supported by an NSERC Discovery Grant(RGPIN-2019-05204);Killam Accelerator Research Fellowship(AWD-018101).
Objectives To determine how the anti-inflammatory actions of interleukin-10(IL-10)and IL-6 differ across age and physical activity levels.Methods Using a cross-sectional design,fasted blood samples were obtained from ...