薯蔓多糖对高脂血症大鼠降血脂作用研究  

Antilipidemic Effect of Polysaccharides Exfracted from Sweet Potato Vines

作　　者：高荫榆[1] 罗丽萍[1] 王应想[1] 夏冬华[1] 洪雪娥[1] 

机构地区：[1]南昌大学生命科学学院,江西南昌330047

出　　处：《食品科学》2005年第2期197-201,共5页Food Science

基　　金：江西省科技厅农业重大项目

摘　　要：利用实验性高脂血症SD大鼠模型观察薯蔓多糖(PSPV)的降脂作用及对脂肪肝的预防和疗效。实验持续8w,每2w采血一次,用试剂盒测定血清中TC、TG、HDL-C的浓度,通过公式计算LDL-C和AI;索氏抽提测定肝脏中粗脂肪含量,石蜡切片、光镜观察大鼠肝脏细胞。实验表明:PSPV能极显著降低高脂血症大鼠血清中TC、TG、LDL-C含量和AI;同时能极显著降低受试动物肝脏粗脂肪含量,并对脂肪肝有显著的预防和疗效。结果:PSPV对实验性高血脂大鼠具有显著的降血脂及预防和脂肪肝疗效作用。Using the hypercholesterolemia SD rats to observe the antilipidemic and preventing and curing effects of fatty liver by polysaccharides extracted from sweet potato vines. The experiment was lasted for 8w. Taking the blood every 2w, and the TC, TG, HDL-C in the serum were measured by reagent box, LDL-C and AI was got from the formula. The raw fat in liver was measured by Soxhlet extracting and the liver cells were observed by paraffin-sections and optical microscope. Result: PSPV could decrease serum TC, TG, LDL-C, AI and the raw fat in liver would vary remarkably. The fatty liver was prevented and cured effectively too. Conclusion: PSPV had very significant effect of antilipidemic and preventing and curing fatty liver on the hypercholesterolemia rats.

关 键 词：薯蔓 多糖 降血脂作用 脂肪肝 

分 类 号：O636.1[理学—高分子化学]