Jeavons综合征的临床特点和脑电分析  

Clinical manifestations and EEG features of Jeavons syndrome

作　　者：黎冰梅[1] 廖卫平[1] 何小诗[1] 邓宇虹[1] 刘晓蓉[1] 王剑威[1] 

机构地区：[1]广州医学院第二附属医院神经内科,510260

出　　处：《中华神经医学杂志》2005年第6期596-598,601,共4页Chinese Journal of Neuromedicine

摘　　要：目的探讨Jeavons综合征的临床特点、脑电学特征及治疗。方法对2例患者的症状学、临床脑电学特征及抗癫痫药物治疗的反应进行观察。结果2例均儿童起病,表现为反复的眼睑肌阵挛伴或不伴短暂失神,脑电图特征为泛化性的双侧对称的3￣6Hz棘慢波或多棘慢波发放,常由特征性的闭眼或闪光刺激诱发或发作加重和时间延长。结论Jeavons综合征由于复杂的症状学和抗癫痫药物的影响所致的脑电图变化的遮蔽,常导致漏诊,Video-EEG对明确诊断有重要价值。Objective To explore the clinical manifestations,EEG features and treatment of Jeavons syndrome. Methods The clinical manifestations,ictal EEG features and the response to antiepileptic drugs were observed in 2 patients with jeavons syndrome. Results Both cases,with childhood-onset,manifested themselves with iterative eyelid myoclonia accompanied or not accompanied by transient absences. Their EEG was characterized by generalized discharges of 3~6 Hz bilaterally symmetrical polyspikes and slow waves induced by eye closure and photosensitivity. Conclusion Jeavons syndrome is liable to underdiagnosis due to the subtle clinical semiology and the masking of EEG changes by antiepileptic drugs. Video-EEG analysis is often needed for confirmative diagnosis of jeavons syndrome.

关 键 词：临床特点 综合征 脑电分析 VIDEO-EEG 抗癫痫药物治疗 脑电图变化 时间延长 闪光刺激 脑电学 症状学 棘慢波 肌阵挛 

分 类 号：R742.1[医药卫生—神经病学与精神病学]