离子阱串联质谱法检测鱼肉中指示性多氯联苯  

Determination of Polycholorinated Biphenyls in Fish by Gas Chromatography-Ion Trap Tandem Mass Spectrometry

作　　者：李敬光[1] 赵云峰[1] 吴永宁[1] 

机构地区：[1]中国疾病预防控制中心营养与食品安全所,北京100050

出　　处：《分析化学》2005年第9期1223-1226,共4页Chinese Journal of Analytical Chemistry

基　　金：国家重点基础研究发展规划项目(No.2003CB415001);国家"十五"重大科技专项<食品安全关键技术>(No.2001BA804A13;2002BA804A19);国家高新技术项目国际合作重点项目(No.2002AA217031)课题资助

摘　　要：建立了使用离子阱串联质谱技术和同位素稀释技术准确测定鱼肉中的7种指示性多氯联苯(PCB)单体的方法.方法的检出限为0.025～0.068 ng/g, 6个加标鱼样(添加水平1 ng/g)中7个单体的回收率为87.2%～103.7%, RSD为3.2%～8.7%(n=6).本方法定量准确可靠,可用于食品中指示性PCB的测定.A method has been developed for the determination of 7 indicator polycholorinated biphenyls （PCBs） in fish using isotope dilution gas chromatography-ion trap tandem mass spectrometry （GC-ITMS）. Before extraction by Soxhlet, the samples were spiked with surrogates. The sample extract were cleaned-up by acid silica column and basic alumina column. Quantification was conducted by GC-ITMS with mutiple reaction monitor. The detection limits of 7 indicator polycholorinated biphenyls were 0.025 - 0.068 ng/g. The average recoveries of 6 fortified fish samples were in the range of 87.2% -103.7% （adding 1 ng/g）, RSDs were in the range of 3.2% - 8.7%. Results show that the method is suitable for the determination of indicator PCBs in fish sample.

关 键 词：多氯联苯 离子阱质谱 同位素稀释 串联质谱法 指示性 离子阱 鱼肉 检测 准确测定 稀释技术 

分 类 号：TS254.7[轻工技术与工程—水产品加工及贮藏工程]