黄酒对实验性铅中毒的拮抗作用研究  

Studies on the Antagonistic Action of Yellow Wine on Lead Poisoning in the Mice Experiment

作　　者：倪赞[1] 寿春波 史锋[1] 朱成钢[1] 谢广发 

机构地区：[1]浙江大学生命科学学院浙江大学生物化学研究所,杭州310029 [2]湖州市安吉县农业局,湖州313300 [3]浙江古越龙山绍兴酒股份有限公司,绍兴312000

出　　处：《中国食品学报》2007年第2期38-41,共4页Journal of Chinese Institute Of Food Science and Technology

摘　　要：为了研究黄酒对小鼠铅水平的影响,建立了小鼠实验性铅中毒模型。将ICR小鼠随机分成空白对照组、模型对照组和黄酒剂量(3个剂量)组。空白对照组饲喂基础饲料,模型对照组连续饲喂高铅饲料,3个剂量组按高、中、低剂量分别饲喂黄酒,并同时饲喂高铅饲料。受试后30d,用等离子体发射光谱法(ICP-AES)测定小鼠血液、肝脏和骨骼的铅含量,结果表明:高、中、低剂量黄酒均能够显著降低小鼠血液和肝脏的铅含量,黄酒对小鼠实验性铅中毒有显著的拮抗作用。In order to investigate the influence of Yellow Wine on lead level in the mice, mice lead poisoning model was established and the mice was randomly divided into five groups： control group, which was fed with basal feed continually; positive control group, which was fed with high lead feed continually; experimental group, which were divided into three subgroup which was feed with high, middle and low dosage of yellow wine respectively. At the same time, the experimental groups were also fed with high lead feed continually. 30 th day after administration, lead content in the mice blood, liver and femur were evaluated and assayed by ICP-AES. Results showed that high, middle and low dosage of yellow wine were all decrease the lead content of the mice blood and liver. Yellow wine has obviously antagonistic action on the lead poisoning in the mice experiment.

关 键 词：黄酒 铅中毒 拮抗作用 等离子体发射光谱法 

分 类 号：TS262.4[轻工技术与工程—发酵工程]