姜油树脂/β-环糊精包合物的稳定性考察  

Stability of Ginger oleoresin/β-cyclodextrin inclusion complex

作　　者：刘利萍[1] 毛威 王秀珍[1] 楼琼瑜[1] 

机构地区：[1]绍兴文理学院化学化工学院,浙江绍兴312000 [2]绍兴市药品检验所,浙江绍兴312000

出　　处：《华西药学杂志》2007年第3期310-311,共2页West China Journal of Pharmaceutical Sciences

基　　金：浙江省教育厅(No:20041229);绍兴市科技局(No:2005162)基金资助

摘　　要：目的考察姜油树脂/β-环糊精(β-CD)包合物的稳定性。方法分别对姜油树脂/β-CD包合物和混合物进行10 d高温(40℃、60℃、80℃),高湿(RH 75%、92.5%)和强光(4×103lx)的实验。用紫外分光光度法测定总姜酚的残留量。结果在温度、湿度和光照的条件下,包合物中总姜酚的含量显著高于混合物,配对t检验表明,二者具有显著性差异(P<0.05)。结论姜油树脂形成包合物后稳定性显著地提高。OBJECTIVE To compare the stability of Ginger oleoresin/β- CD inclusion complex with Ginger oleoresin. METHODS The stability experiment was carried under the storage conditions of high temperature （40℃, 60℃, 80℃ ）, high humidity （ RH 75%, 92.5% ）and high light （4 ×10^3 lx）. The contents of total gingerol were measured by ultraviolet spectrophotometry. RESULTS When they were stored under above conditions for 10 days, the stability of Ginger oleoresin/β - CD inclusion complex was obviously higher than that of mixture, and exhibited significant difference by paired sample T - test （ P 〈 0.05）. CONCLUSION The β - CD inclusion complex could obviously increase the stability of Ginger oleoresin.

关 键 词：姜油树脂 Β-环糊精 包合物 稳定性 

分 类 号：R913[医药卫生—药学]