身材矮小儿童染色体核型分析  

Chromosome analysis on heredity of the children who with short stature

作　　者：宫剑[1] 王秀娣[1] 曹淑燕[1] 杨少燕[1] 陈小芳[1] 刘宝华[2] 

机构地区：[1]温州医学院附属二院科研中心,浙江温州325027 [2]温州医学院附属二院康复科

出　　处：《中国妇幼保健》2008年第10期1364-1365,共2页Maternal and Child Health Care of China

摘　　要：目的:探讨身材矮小儿童细胞遗传学方面的原因。方法:对我院2003年以来147例身材矮小儿童进行外周血淋巴细胞G显带染色体核型分析检查。结果:发现异常核型34例,占全部患者的23.12%,其中常染色体异常21三体1例,占全部被检患者的0.68%,性染色体异常33例,占全部被检患者的22.44%。结论:性染色体异常是儿童身材矮小的重要遗传因素,应引起临床医师的高度重视。Objective： To explore the chromosome of the children who with short stature. Methods： 147 children who had growth delay history were analyzed. Results： In 147 cases, abnormal chromosome were 34 cases, the abnormal rate was 23.12%. 1 abnormal case was autosomal abnormality, the abnormal rate was 0. 68%. 33 abnormal cases ware sex chromosome abnormality, the abnormal rate was 22. 44%. Conclusion： Sexchromosome abnormality is an important reason for children who with short stature.

关 键 词：身材矮小 染色体核型 染色体异常 

分 类 号：R394[医药卫生—医学遗传学]